Patents by Inventor Olivia Niebla Perez

Olivia Niebla Perez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100172931
    Abstract: The present invention is related to field of medicine, particularly to the development of pharmaceutical composition containing the NMB1796 protein. The composition described in this invention are able to confer protection against different diseases caused or not by pathogenic agents. The NMB1796 protein was identified as a Neisseria meningitidis outer membrane vesicle (OMV) component, and it was obtained through recombinant DNA technology being its immunogenicity and protective activity evaluated in animal models. Due to the high level of conservation that the NMB1796 coding gene has shown, pharmaceutical compositions containing this protein have a high value as inducers of a cross-reactive immune response. The composition presented in this invention is applicable to the field of human medicine.
    Type: Application
    Filed: June 16, 2008
    Publication date: July 8, 2010
    Inventors: Rolando Pajon Feyt, Olivia Niebla Perez, Gretel Sardinas Garcia, Sonia Gonzalez Blanco, Darien Garcia Diaz, Evelin Caballero Menendez, Karem Cobas Acosta
  • Publication number: 20070166333
    Abstract: Method for the insertion of protein antigens, of recombinant or synthetic origin, in outer membrane vesicles of Gram-negative bacteria without disruption of the vesicle structure, therefore maintaining the immunogenicity and immunostimulatory properties of said vesicles, and with the reported advantage that the immune response generated against the incorporated antigen is superior to the one generated when the antigen is administered alone. The resultant vaccine formulations are useful to increase protective capacity of existing vaccines and allow to extend it against different pathogens, in diseases of bacterial, viral, cancerous or other etiology. The referred formulations are applicable in the pharmaceutical industry as vaccines for therapeutic and preventive use in humans.
    Type: Application
    Filed: November 3, 2004
    Publication date: July 19, 2007
    Inventors: Olivia Niebla Perez, Rolando Pajon Feyt, Sonia Gonzalez Blanco, Alejandro Martin Dunn, Maite Delgado Espina, Hilda Garay Perez, Gerardo Guillen Nieto