Patents by Inventor Olivier BORNERT

Olivier BORNERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-18 POLYPEPTIDES FUSED TO IMMUNE CELL ANTIGEN SPECIFIC BINDING POLYPEPTIDES AND USES THEREOF
    Publication number: 20250188166
    Abstract: The present disclosure relates to fusion immunocytokines comprising antibodies or antigen binding fragments specific for immune cell associated antigens, such as PD-1, and IL-18 polypeptides. Also provided herein are methods of treatment with and methods of manufacture of such fusion immunocytokines.
    Type: Application
    Filed: August 23, 2024
    Publication date: June 12, 2025
    Inventors: Vijaya Raghavan PATTABIRAMAN, Bertolt KREFT, Arnaud GOEPFERT, Olivier BORNERT, Jean-Philippe CARRALOT, Kea MARTIN
  • CONDITIONALLY ACTIVATED IMMUNOCYTOKINES AND METHODS OF USE
    Publication number: 20240417436
    Abstract: The present disclosure relates activatable immunocytokines targeted to immune checkpoint molecules such as PD-1, compositions comprising the activatable immunocytokines, and methods of use thereof. The present disclosure also relates activatable IL-2 polypeptides linked to anti-PD-1 polypeptides (e.g., anti-PD-1 antibodies).
    Type: Application
    Filed: January 11, 2024
    Publication date: December 19, 2024
    Inventors: Vijaya Raghavan PATTABIRAMAN, Bertolt KREFT, Grégory UPERT, Matilde ARÉVALO-RUIZ, Nina RESCHKE, Davor BAJIC, Olivier BORNERT, Arnaud GOEPFERT