Patents by Inventor Olivier Chevreuil

Olivier Chevreuil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azaindole inhibitors of MTP and ApoB
    Patent number: 7838533
    Abstract: The present invention relates to 7-azaindole-based compounds, to processes for the preparation thereof, to pharmaceutical compositions comprising them, and to the use thereof in the preparation of medicaments that are useful as inhibitors of MTP and of ApoB secretion.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: November 23, 2010
    Assignee: Merck Patent GmbH
    Inventors: Alyx Caroline Guevel, Catherine Vidal, Bruno Roux, Olivier Chevreuil
  • Thiazolylimidazole derivatives and their use as inhibitors of microsomal triglyceride transfer protein
    Patent number: 7767819
    Abstract: The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R1, R2, R3, R4, R5, R6, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Grant
    Filed: January 17, 2005
    Date of Patent: August 3, 2010
    Assignee: Merck Patent GmbH
    Inventors: Philippe Guedat, Olivier Chevreuil, Thierry Convard
  • THIAZOLYLIMIDAZOLE DERIVATIVES AN THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN
    Publication number: 20100137601
    Abstract: The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R1, R2, R3, R4, R5, R6, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Application
    Filed: February 4, 2010
    Publication date: June 3, 2010
    Inventors: Philippe GUEDAT, Olivier Chevreuil, Thierry Convard
  • Aroyl-O-piperidine derivatives for the treatment of diabetes-related problems
    Patent number: 7723358
    Abstract: The present invention relates to derivatives of aroyl-O-piperidine structure of the general formula (I): in which R1, R2, R3 and R4 are as defined in the description. Application of the compounds of the formula (I) to the treatment of hyper-triglyceridaemia, hypercholesterolaemia and dyslipidaemia, and to the prevention or treatment of obesity.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: May 25, 2010
    Assignee: Merck Patent GmbH
    Inventors: Philippe Guedat, Francois Collonges, Olivier Chevreuil, Hervé Dumas, Marie Noelle Denault, Stéphane Yvon, Peter Kane, Julia Lainton, Avril Robertson, Bernd Wendt
  • Novel Azaindole Inhibitors of Mtp and Apob
    Publication number: 20090036481
    Abstract: The present invention relates to 7-azaindole-based compounds, to processes for the preparation thereof, to pharmaceutical compositions comprising them, and to the use thereof in the preparation of medicaments that are useful as inhibitors of MTP and of ApoB secretion.
    Type: Application
    Filed: June 28, 2005
    Publication date: February 5, 2009
    Inventors: Alyx Caroline Guevel, Catherine Vidal, Bruno Roux, Olivier Chevreuil
  • Thiazolylimidazole Derivatives and Their Use as Inhibitors of Microsmal Triglyceride Transfer Protein
    Publication number: 20080214610
    Abstract: The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R1, R2, R3, R4, R5, R6, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Application
    Filed: January 17, 2005
    Publication date: September 4, 2008
    Inventors: Philippe Guedat, Olivier Chevreuil, Thierry Convard
  • Aroyl-O-Piperidine Derivatives for the Treatment of Diabetes-Related Problems
    Publication number: 20070254919
    Abstract: The present invention relates to derivatives of aroyl-O-piperidine structure of the general formula (I): in which R1, R2, R3 and R4 are as defined in the description. Application of the compounds of the formula (I) to the treatment of hyper-triglyceridaemia, hypercholesterolaemia and dyslipidaemia, and to the prevention or treatment of obesity.
    Type: Application
    Filed: May 19, 2005
    Publication date: November 1, 2007
    Inventors: Philippe Guedat, Francois Collonges, Olivier Chevreuil, Herve Dumas, Marie Denault, Stephane Yvon, Peter Kane, Julia Lainton, Avril Robertson, Bernd Wendt
  • 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors
    Publication number: 20040034028
    Abstract: The present invention relates to compounds of the formula (I): in which: Z represents biphenyl optionally substitute in position 2′, 3′, 4′, 5′ and 6′ with one or more substitutents chosen from trihalomethyl and trihalomethoxy; Het represents quinolyl, quinoxalyl or pyridyl optionally substituted with one or more substitutents chosen from halo, cyano, nitro, (C1-C6)alkyl, (C6-C12)aryl, (C1-C6)alkoxy, hydroxyl, (C1-C6)thioalkoxy, carboxyl and (C1-C6)alkoxycarbonyl, or pharmaceutically acceptable salts thereof. These compounds are useful as inhibitors of microsomal triglyceride transfer protein and as inhibitors of the secretion of B apoproteins.
    Type: Application
    Filed: May 22, 2003
    Publication date: February 19, 2004
    Inventors: Alyx-Caroline Guevel, Didier Festal, Francois Collonges, Daniel Guerrier, Olivier Chevreuil