Abstract: The invention is a nanowire-comprising device for detecting at least one target biomolecule. The nanowires are placed between a substrate and a multilayer structure. The multilayer structure lies between the nanowires and a sample liable to contain a target biomolecule. The multilayer structure comprises a functionalization surface making contact with the sample. When light is emitted from the functionalization surface, fluorescence light for example, at least one nanowire allows the light to be detected. The fluorescence light may indicate the presence or absence of a target biomolecule on the functionalization surface.

Abstract: A process for manufacturing a micro-fluidic device, the device including a substrate made of thermoplastic polymer having a face called the upper face and a first micro-fluidic circuit that includes at least one aperture that opens onto the upper face, and a component bearing pads arranged to become anchored in the substrate on the periphery of the aperture, the process including the following steps: heating so that the anchoring pads of the component reach a temperature at least equal to the glass-transition temperature of the substrate; fastening the component to the substrate by embedding then anchoring its pads in the substrate.

Abstract: The invention relates to a method for integrating structures in a support, which comprises the steps: a) supplying a support comprising a front face and a rear face, and through cavities each delimited by a wall designated through wall; b) inserting into each of the through cavities a structure, provided with a first face and a second face connected by a contour, the first face and the front face being coplanar, the through cavities and/or the structures being laid out to leave a peripheral space; c) filling the peripheral space with a sealing material so as to maintain the structures to the support; The peripheral space has a radial extension length which decreases from the rear face to the front face.

Abstract: The invention relates to a method for integrating structures in a support, which comprises the steps: a) supplying a support comprising a front face and a rear face, and through cavities each delimited by a wall designated through wall; b) inserting into each of the through cavities a structure, provided with a first face and a second face connected by a contour, the first face and the front face being coplanar, the through cavities and/or the structures being laid out to leave a peripheral space; c) filling the peripheral space with a sealing material so as to maintain the structures to the support; The peripheral space has a radial extension length which decreases from the rear face to the front face.

Abstract: The invention relates to a surface pump comprising a network (3) of microfluidic channels (5) and pumping means (7). Said network of microfluidic channels includes a set of microfluidic accesses (9) distributed in a predetermined domain (11) suited to covering a surface source of a fluid of interest, and said pumping means comprise at least one microfluidic actuating circuit (11) intersecting said network of microfluidic channels on a plurality of deformable membrane intersecting zones (17) forming a set of valves (19) suited to causing a peristaltic effect pumping of said fluid of interest circulating in said network of microfluidic channels from said set of microfluidic accesses to at least one sink (21) connected to said network of microfluidic channels.

Abstract: The invention provides a device for the gravimetric detection of particles in a fluid medium, comprising a flat electromechanical oscillator (1), means for supporting the oscillator, means (15a, 15b, 15c, 15d) for actuating said oscillator and, on either side of the plane of the oscillator (1), two cavities (3, 5) enabling the oscillator (1) to vibrate when it is activated by the actuation means (15a, 15b, 15c, 15d), characterized in that at least one of the two cavities (3, 5) forms an integral part of a channel (2, 4) for the passage of a fluid over at least one of the faces (1a, 1b) of the oscillator and in that said actuation means (15a, 15b, 15c, 15d) take the form of at least one electrode (15a, 15b, 15c, 15d) lying in the same plane as that of the electromechanical oscillator and at a defined distance (g) from the oscillator, so as to ensure that the oscillator vibrates in its plane.

Abstract: A microreactor is shown having an inlet or feed channel, an inlet or feed zone for a flow of fluid, a reaction zone, an outlet zone and an outlet or evacuation channel, the zones and channels being in fluid communication, and at least one compound such as an enzyme capable of producing a biological or biochemical reaction with at least one constituent of the flow of fluid, the compound being attached to the surfaces of the inlet zone, reaction zone, and outlet zone.

Abstract: The invention provides a device for the gravimetric detection of particles in a fluid medium, comprising a flat electromechanical oscillator (1), means for supporting the oscillator, means (15a, 15b, 15c, 15d) for actuating said oscillator and, on either side of the plane of the oscillator (1), two cavities (3, 5) enabling the oscillator (1) to vibrate when it is activated by the actuation means (15a, 15b, 15c, 15d), characterized in that at least one of the two cavities (3, 5) forms an integral part of a channel (2, 4) for the passage of a fluid over at least one of the faces (1a, 1b) of the oscillator and in that said actuation means (15a, 15b, 15c, 15d) take the form of at least one electrode (15a, 15b, 15c, 15d) lying in the same plane as that of the electromechanical oscillator and at a defined distance (g) from the oscillator, so as to ensure that the oscillator vibrates in its plane.

Abstract: A lab-on-a-chip comprising a support plate, at least one fluidic network formed in a fluidic plate bonded onto the support plate, and a cover plate bonded onto the fluidic plate and covering the fluidic network. The fluidic network, at a first end, is connected to an inlet orifice allowing entry of a liquid to be sprayed and, at a second end, to a first end of an outlet channel for the liquid to be sprayed, formed in the fluidic plate. The fluidic plate is extended by a pointed electrospray nozzle at which the second end of the outlet channel forms the electrospray outlet of the lab-on-a-chip. The cover plate has a pointed extension forming a roof for that part of the channel located in the electrospray nozzle.

Abstract: The invention relates to an on-chip laboratory comprising a fluidic network made in a substrate, a fluid inlet orifice connected to the fluidic network and a fluid outlet orifice connected to the fluidic network. The substrate comprises a planar layer (53) in which the fluidic network and an electronebulization nozzle (65) are made, the electronebulization nozzle overhanging relatively to the remainder of the substrate (51, 52) and comprising a channel (64), one end of which is connected to the fluidic network and the other end of which forms said fluid outlet orifice, the channel being fitted with electrical conduction means (59) forming at least one electrode.

Abstract: The invention relates to a device for displacement of at least a small volume of liquid (5) under the effect of an electrical control, including a substrate (1) provided with first electrically conducting means (2), the device also comprising second electrically conducting means (3) arranged facing the first electrically conducting means (2), the first electrically conducting means and the second electrically conducting means possibly being connected to electrical power supply means to enable the application of electrostatic forces to the small liquid volume (5). The second electrically conducting means include at least one conducting wire (3) arranged parallel to the substrate and at a fixed distance from the substrate to enable displacement of the small volume of liquid (5) along said conducting wire (3) under the effect of the applied electrostatic forces.

Abstract: Microreactor comprising an inlet or feed channel, an inlet or feed zone (1) for a flow of fluid, a reaction zone (2), an outlet zone (3) and an outlet or evacuation channel, said zones (1, 2, 3) and channels (46, 48) being in fluid communication, and at least one compound such as an enzyme capable of producing a biological or biochemical reaction with at least one constituent of said flow of fluid, said compound being attached to the surfaces of said inlet zone (1), reaction zone (2), and outlet zone (3).

Abstract: The method for production of a component with a micro-joint comprises a first step of deposition of a layer of polymer designed to constitute an assembly joint on a transfer substrate, a second step of bringing the polymer layer into contact with a micro-structured substrate and a third step of removing the transfer substrate. Due to the difference of the chemical affinity between the polymer layer and the transfer substrate on the one hand and the chemical affinity between the polymer layer and the micro-structured substrate on the other hand, the zones of the polymer layer, which are in contact with the micro-structured substrate during the second step, remain on the micro-structured substrate after the third step. These zones constitute the assembly joint.

Abstract: The invention relates to a device for displacement of at least a small volume of liquid (5) under the effect of an electrical control, including a substrate (1) provided with first electrically conducting means (2), the device also comprising second electrically conducting means (3) arranged facing the first electrically conducting means (2), the first electrically conducting means and the second electrically conducting means possibly being connected to electrical power supply means to enable the application of electrostatic forces to the small liquid volume (5). The second electrically conducting means include at least one conducting wire (3) arranged parallel to the substrate and at a fixed distance from the substrate to enable displacement of the small volume of liquid (5) along said conducting wire (3) under the effect of the applied electrostatic forces.

Abstract: A miniaturized photoacoustic spectrometer made from a series of stacked substrates. An infrared source is formed in a first substrate. A filter is formed in a second substrate. A micro-trough is machined in a third substrate and a microphone is formed in a fourth substrate. A fifth substrate has a metallic deposit for reflecting light emitted by the infrared source. Resin sealing is provided between the substrates.