Patents by Inventor Olivier Corminboeuf

Olivier Corminboeuf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorinated bridged spiro[2.4]heptane derivatives as ALX receptor agonists
    Patent number: 9139524
    Abstract: The present invention relates to fluorinated bridged spiro[2.4]heptane derivatives of formula (I), wherein n and R1 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: September 22, 2015
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Olivier Corminboeuf, Davide Pozzi
  • 1-(p-tolyl)cyclopropyl substituted Bridged Spiro[2.4]Heptane Derivatives as ALX Receptor Agonists
    Publication number: 20150141482
    Abstract: The present invention relates to 1-(p-tolyl)cyclopropyl substituted bridged spiro[2.4]heptane derivatives of formula (I), wherein R1 is as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Application
    Filed: May 15, 2013
    Publication date: May 21, 2015
    Inventors: Olivier Corminboeuf, Sylvaine Cren
  • Fluorinated Bridged Spiro[2.4]Heptane Derivatives as ALX Receptor Agonists
    Publication number: 20150118258
    Abstract: The present invention relates to fluorinated bridged spiro[2.4]heptane derivatives of formula (I), wherein n and R1 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Application
    Filed: May 15, 2013
    Publication date: April 30, 2015
    Inventors: Olivier Corminboeuf, Davide Pozzi
  • Piperazines as antimalarial agents
    Patent number: 8889688
    Abstract: The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: November 18, 2014
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Christoph Boss, Olivier Corminboeuf, Bibia Heidmann, Romain Siegrist
  • Oxazolyl-methylether derivatives as ALX receptor agonists
    Patent number: 8846733
    Abstract: The invention relates to oxazolyl-methylether derivatives of formula (I), wherein R1, R2, R3, R4 and R5 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: September 30, 2014
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • Oxazole and thiazole derivatives as ALX receptor agonists
    Patent number: 8674111
    Abstract: The invention relates to oxazole and thiazole derivatives of formula (I), wherein A, E, X, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: March 18, 2014
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • Fluorinated aminotriazole derivatives
    Patent number: 8580831
    Abstract: The invention relates to fluorinated aminotriazole derivatives of formula (I), wherein A, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 12, 2013
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • Bridged spiro [2.4] heptane derivatives as ALX receptor and/or FPRL2 agonists
    Patent number: 8563714
    Abstract: The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and/or FPRL2 agonists for the treatment of inflammatory and obstructive airways diseases.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: October 22, 2013
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • Hydroxylated Aminotriazole Derivatives as ALX Receptor Agonists
    Publication number: 20130267569
    Abstract: The invention relates to hydroxylated aminotriazole derivatives of formula (I), wherein Q, R1, R2, R3 and R4 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 10, 2013
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • OXAZOLYL-METHYLETHER DERIVATIVES AS ALX RECEPTOR AGONISTS
    Publication number: 20130261159
    Abstract: The invention relates to oxazolyl-methylether derivatives of formula (I), wherein R1, R2, R3, R4 and R5 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 3, 2013
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • Aminotriazole derivatives as ALX agonists
    Patent number: 8536209
    Abstract: The invention relates to aminotriazole derivatives of formula (I), wherein A, E, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: September 17, 2013
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • PIPERAZINES AS ANTIMALARIAL AGENTS
    Publication number: 20120316178
    Abstract: The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.
    Type: Application
    Filed: January 4, 2011
    Publication date: December 13, 2012
    Inventors: Hamed Aissaoui, Christoph Boss, Olivier Corminboeuf, Bibia Heidmann, Romain Siegrist
  • BRIDGED SPIRO [2.4] HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS
    Publication number: 20120115841
    Abstract: The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and/or FPRL2 agonists for the treatment of inflammatory and obstructive airways diseases.
    Type: Application
    Filed: May 17, 2010
    Publication date: May 10, 2012
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • OXAZOLE AND THIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS
    Publication number: 20120115916
    Abstract: The invention relates to oxazole and thiazole derivatives of formula (I), wherein A, E, X, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Application
    Filed: June 11, 2010
    Publication date: May 10, 2012
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • FLUORINATED AMINOTRIAZOLE DERIVATIVES
    Publication number: 20120101138
    Abstract: The invention relates to fluorinated aminotriazole derivatives of formula (I), wherein A, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds.
    Type: Application
    Filed: June 7, 2010
    Publication date: April 26, 2012
    Inventors: Daniel Bur, Olivier Corminboeuf, Sylvaine Cren, Corinna Grisostomi, Xavier Leroy, Sylvia Richard-Bildstein
  • Bicyclononene derivatives
    Patent number: 8138340
    Abstract: The invention relates to novel bicyclononene derivatives of Formula (I); and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: March 20, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Olivier Bezencon, Christoph Boss, Daniel Bur, Olivier Corminboeuf, Walter Fiśchli, Corinna Grisostomi, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Piperazines as antimalarial agents
    Patent number: 8067419
    Abstract: The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, especially malaria.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: November 29, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Christoph Boss, Olivier Corminboeuf, Corinna Grisostomi, Solange Meyer
  • TETRAHYDROISOQUINOLINES AS ANTIMALARIAL AGENTS
    Publication number: 20110281869
    Abstract: The invention relates to novel tetrahydroisoquinoline derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.
    Type: Application
    Filed: May 18, 2009
    Publication date: November 17, 2011
    Inventors: Hamed Aissaoui, Christoph Boss, Olivier Corminboeuf, Marie-Celine Frantz
  • NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS
    Publication number: 20110224210
    Abstract: The invention relates to novel bis-amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.
    Type: Application
    Filed: November 18, 2009
    Publication date: September 15, 2011
    Inventors: Hamed Aissaoui, Christoph Boss, Olivier Corminboeuf, Marie-Celine Frantz, Corinna Grisostomi
  • Secondary amines as renin inhibitors
    Patent number: 7968720
    Abstract: The invention relates to novel secondary amine derivatives of formula (I) and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: June 28, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Olivier Bezencon, Daniel Bur, Olivier Corminboeuf, Daniel Dube, Corinna Grisostomi, Dwight MacDonald, Dan McKay, David Powell, Lubos Remen, Sylvia Richard-Bildstein, John Scheigetz, Michel Therien, Thomas Weller