Abstract: A process for the preparation of a compound of formula (I) wherein Q is CH or N; Y is NO2 or CN; Z is CHR3, O, NR3 or S; R1 and R2 are C1-C8 alkyl or together form an alkylene bridge having two or three carbon atoms; by reacting a compound of formula H2C=C(X)CH2NCS wherein X is a leaving group, with a chlorinating agent in the presence of a catalytic amount of SO2. to form a compound of formula (III) and the compound of formula (III) is reacted with a compound of formula R1NHC(=QY)ZR2 wherein R1, R2, Y, Z and Q are as defined for compound (I).

Abstract: There are described a process for the preparation of a compound of formula in free form or in salt form, wherein Q is CH or N; Y is NO2 or CN; Z is CHR3, O, NR3 or S; R1 and R2 are, for example, C1-C8 alkyl or together form an alkylene bridge; R3 is H or C1-C1-2 alkyl which is unsubstituted or substituted by R4; and R4 is unsubstituted or substituted aryl or heteroaryl; wherein a) a compound of formula (II), wherein X is a leaving group, is reacted with a chlorinating agent to form a compound of formula (III), in free form or in salt form; and b) the compound of formula (III) thereby obtained is reacted with a compound of formula wherein R1, R2, Y, Z and Q are as defined for compound (I); in which process the chlorination according to process step a) is performed using a chlorinating agent in the presence of catalytic amounts of SO2; a process for the preparation of a compound of formula (III) according to process a) hereinbefore; and the use of the compouds of formulae (II), (III) and (IV) in a process as de