Abstract: The present invention relates to methods for purifying heterologous antibodies from caprine milk, such as goat milk. The present invention includes protein A based affinity chromatography to obtain purified transgenically expressed antibodies, in particular concentrates free from endogenous caprine antibodies.

Abstract: The present invention relates to methods for purifying heterologous antibodies from caprine milk, such as goat milk. The present invention includes protein A based affinity chromatography to obtain purified transgenically expressed antibodies, in particular concentrates free from endogenous caprine antibodies.

Abstract: The present invention relates to a newly identified hydrolase from thermophilic microorganisms having thermostable properties, and more specifically, to a novel thermostable hydrolase showing high activity at high temperatures.

Abstract: The invention concerns a modified nitrilase with modulated selectivity, characterized in that it comprises in position 162 an amino acid residue different from the original amino acid residue.

Abstract: An enzymatic catalyst in the granular form which is non-dispersible in water comprising an inner core provided with a coating which coating comprises an enzymatic material characterised in that the coating has a thickness of from 30 to 400 microns and the ratio of the size of the core to the thickness of the coating is from 2 to 20. A method for the preparation of the catalyst and the use of the catalyst in the conversion of 2-hydroxy-4-methylthio butyronitrile to ammonium 2-hydroxy-4-methylthio butanoate is also claimed.

Abstract: The present invention relates to processes for the production of acyl compounds using an esterase having thermostable properties, and to products of such processes.

Abstract: The present invention relates to a newly identified hydrolase from thermophilic microorganisms having thermostable properties, and more specifically, to a novel thermostable hydrolase showing high activity at high temperatures.

Abstract: An enzymatic catalyst in the granular form which is non-dispersible in water comprising an inner core provided with a coating which coating comprises an enzymatic material characterised in that the coating has a thickness of from 30 to 400 microns and the ratio of the size of the core to the thickness of the coating is from 2 to 20. A method for the preparation of the catalyst and the use of the catalyst in the conversion of 2-hydroxy-4-methylthio butyronitrile to ammonium 2-hydroxy-4-methylthio butanoate is also claimed.

Abstract: The invention concerns a method for preparing &agr;-phenylalanine ester with substantially enantiomeric purity of formulae (I) and (II) wherein Alk represents a linear or branched C1-C6 alkyl radical, characterized in that it consists in contacting a mixture of &agr;-phenylalanine ester enantiomers with a lipase, a protease or an esterase.

Abstract: The invention concerns a method for preparing methionine aminoamide. The invention also concerns the preparation of methionine without co-production of salts, from an aqueous solution containing essentially methionine aminonitrile by producing during a first step aminoamide followed by two complementary steps.

Abstract: The present invention relates to an enzyme with amidase activity, particularly towards substrates of the oligomer type derived from PA 6.

Abstract: The present invention relates to a process for the enzymatic hydrolysis of polyamides 6.6 to give adipic acid monomers and hexamethylenediamine monomers. The present invention further relates to an enzyme with amidase activity particularly towards substrates of the oligomer type derived from PA 6.6 and/or PA 6, said enzyme being characterized in that it consists of a peptide sequence corresponding to SEQ ID NO: 1 in the attached sequence listing and/or at least one polypeptide homologous to this sequence. The invention further relates to the DNA coding for said enzyme and to the biological precursors thereof The invention further relates to the microorganisms capable of producing this enzyme and to the hydrolysis process in which this enzyme and/or these microorganisms are applied.

Abstract: This invention relates to a process for the preparation of 2-hydroxy-4-methylthiobutyric acid or the ammonium salt of 2-hydroxy-4-methylthiobutyric acid by enzymatic hydrolysis of 2-hydroxy-4-methylthiobutyronitrile, comprising: a) preparing a biological material having a nitrilase activity; b) immobilizing the biological material, c) exposing the 2-hydroxy-4-methylthiobutyronitrile to the biological material thus immobilized to obtain the ammonium salt of 2-hydroxy-4-methylthiobutyric acid; and d) optionally converting the salt obtained to the corresponding acid.

Abstract: A method for the enzymatic hydrolysis of racemic .alpha.-substituted 4-methylthiobutyronitriles into racemic .alpha.-substituted 4-methylthiobutyric acid using a nitrilase from Alcaligenes faecalis, Gordona terrae or Rhodococcus sp.

Abstract: Contaminating trace amounts of byproduct dihalocarboxylic acids or salts thereof are removed from aqueous solutions which comprise less than 1,000 ppm of same and at least 20% by weight of amino acids or amino acid derivatives, to render such aqueous solutions nonirritating to biological membranes and suitable for cosmeticology applications, by directly contacting the original aqueous solutions with either (a) about 1 to 100 ppm of a microorganism producing an enzyme specific for the decomposition of said dihalocarboxylic acids or salts thereof, or (b) about 0.1 to 10 ppm of such enzyme, per se.