Patents by Inventor OLivier Freund

OLivier Freund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6387396
    Abstract: A composition containing a plurality of multicellular vesicles and at least one nucleic acid, at least one part of which is found included inside the multilamellar vesicles. Each of the vesicles is formed of a succession of lamellar bi-layers extending from each vesicle center to its periphery and including at least one surfactant agent. The bi-layers are concentric and are separated by a liquid medium. Such compositions can be used in pharmaceutics, particularly gene therapy, and in in vitro and in vivo transfection.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: May 14, 2002
    Assignee: Capsulis
    Inventors: Patrick Mahy, Didier Roux, René Laversanne, Joëlle Amedee, OLivier Freund
  • Publication number: 20020012696
    Abstract: The invention concerns a composition containing at least one nucleic acid a part of which at least is enclosed in multilamellar vesicles, characterised in that said vesicles consist of two layers comprising at least one surfactant, the said two layers being concentric and giving said vesicles an onion-like structure. The surfactants used are non-cationic surfactants. The invention concerns the use of such compositions in pharmaceutics, particularly in gene therapy and in in vitro and in vivo transfection.
    Type: Application
    Filed: January 6, 1999
    Publication date: January 31, 2002
    Inventors: PATRICK MAHY, DIDIER ROUX, RENE LAVERSANNE, JOELLE AMEDEE, OLIVIER FREUND