Patents by Inventor Olivier Kitten

Olivier Kitten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTI SPECIFIC MOLECULES
    Publication number: 20240218036
    Abstract: The invention relates to proteins having multi-specific binding abilities by fusion of an OB-fold variant, in particular from the Sac7d family, to the light or heavy chain of an antibody.
    Type: Application
    Filed: February 7, 2024
    Publication date: July 4, 2024
    Applicant: AFFILOGIC
    Inventors: Olivier KITTEN, Mathieu CINIER, Simon HUET
  • ANTI-FACTOR C3 SAC7D VARIANTS AND THEIR MEDICAL USE FOR TREATING COMPLEMENT-MEDIATED DISORDERS
    Publication number: 20240166692
    Abstract: The invention relates to a polypeptide comprising a variant of a protein of the Sac7d family that specifically binds to the complement component 3 (C3) and/or the component C3b obtained after hydrolysis of C3, and inhibits the complement cascade.
    Type: Application
    Filed: March 18, 2022
    Publication date: May 23, 2024
    Inventors: Mathieu CINIER, Anne CHEVREL, Olivier KITTEN
  • COMPOUNDS AND METHODS FOR EXTENDING HALF LIFE OF BIOMOLECULES
    Publication number: 20240124531
    Abstract: The invention relates to variants of OB-fold proteins, in particular of the Sac7d family that bind to human and mouse serum albumin and that can be used to increase serum half-life of elements associated therewith.
    Type: Application
    Filed: February 14, 2022
    Publication date: April 18, 2024
    Inventors: Mathieu CINIER, Olivier KITTEN
  • Multi specific molecules
    Patent number: 11932674
    Abstract: The invention relates to proteins having multi-specific binding abilities by fusion of an OB-fold variant, in particular from the Sac7d family, to the light or heavy chain of an antibody.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: March 19, 2024
    Assignee: AFFILOGIC
    Inventors: Olivier Kitten, Mathieu Cinier, Simon Huet
  • Non-antibody ligands for detecting target proteins
    Patent number: 11714090
    Abstract: The invention relates generally to synthetic non-antibody protein scaffolds (synNAPS) that differentially detect or quantitate a target insecticidal protein in a complex biological matrix comprising the target protein and a non-target insecticidal protein and to methods of using the synNAPS in immunoassays, and more particularly to monoclonal antibodies and immunoassays for the differential detection and quantitation of a wild-type crystal protein, such as a wild-type-Cry1Ab, from Bacillus thuringiensis and hybrid crystal proteins, which comprise all or a significant portion of the wild-type Cry protein in complex biological samples comprising both the wild-type Cry protein and one or more of the hybrid Cry proteins.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: August 1, 2023
    Assignee: Syngenta Participations AG
    Inventors: Michele Yarnell, Anne Chevrel, Olivier Kitten, Scott Young
  • ANTI-HER2 POLYPEPTIDES DERIVATIVES AS NEW DIAGNOSTIC MOLECULAR PROBES
    Publication number: 20230203129
    Abstract: The present invention provides new polypeptide derivatives binding to Human Epidermal Growth Factor Receptor 2 (HER2) and their conjugates thereof, and to their use as a diagnostic agent, particularly for early detection, patient stratification and treatment monitoring of forms of cancer characterized by over-expression of HER2.
    Type: Application
    Filed: December 16, 2020
    Publication date: June 29, 2023
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Erika REITANO, Alessandro MAIOCCHI, Luisa POGGI, Federico CRIVELLIN, Simon HUET, Mathieu CINIER, Olivier KITTEN
  • VARIANTS OF SAC7D AND THEIR USE IN CANCER THERAPY
    Publication number: 20230120167
    Abstract: The invention relates to variants of OB-fold proteins, hi particular of the Sac7d family that bind PD-L1 or HSP110 and are able to be used alone or in combination for cancer treatment.
    Type: Application
    Filed: March 10, 2021
    Publication date: April 20, 2023
    Inventors: Mathieu CINIER, Anne CHEVREL, Olivier KITTEN
  • ANTI-HER2 POLYPEPTIDES DERIVATIVES AS NEW DIAGNOSTIC MOLECULAR PROBES
    Publication number: 20230040008
    Abstract: The present invention provides new polypeptide derivatives binding to Human Epidermal Growth Factor Receptor 2 (HER2) and their conjugates thereof, and to their use as a diagnostic agent, particularly for early detection, patient stratification and treatment monitoring of forms of cancer characterized by over-expression of HER2.
    Type: Application
    Filed: December 16, 2020
    Publication date: February 9, 2023
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Erika REITANO, Alessandro MAIOCCHI, Luisa POGGI, Federico CRIVELLIN, Simon HUET, Mathieu CINIER, Olivier KITTEN
  • BINDERS FOR INHIBITING FORMATION OF MULTIMERIC PROTEINS
    Publication number: 20210380647
    Abstract: The invention relates to variants of OB-fold proteins, in particular of the Sac7d family that are able to bind a subunit of a multimeric protein and inhibit the formation of the multimer.
    Type: Application
    Filed: October 6, 2019
    Publication date: December 9, 2021
    Inventors: Olivier KITTEN, Mathieu CINIER, Simon HUET, Anne CHEVREL
  • NON-ANTIBODY LIGANDS FOR DETECTING TARGET PROTEINS
    Publication number: 20210181204
    Abstract: The invention relates generally to synthetic non-antibody protein scaffolds (synNAPS) that differentially detect or quantitate a target insecticidal protein in a complex biological matrix comprising the target protein and a non-target insecticidal protein and to methods of using the synNAPS in immunoassays, and more particularly to monoclonal antibodies and immunoassays for the differential detection and quantitation of a wild-type crystal protein, such as a wild-type-Cry1Ab, from Bacillus thuringiensis and hybrid crystal proteins, which comprise all or a significant portion of the wild-type Cry protein in complex biological samples comprising both the wild-type Cry protein and one or more of the hybrid Cry proteins.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 17, 2021
    Applicant: Syngenta Participations AG
    Inventors: Michele YARNELL, Anne CHEVREL, Olivier Kitten, Scott Young
  • Topical compositions comprising OB-fold variants
    Patent number: 10898542
    Abstract: The invention relates to a topical composition containing a variant of an OB-fold protein, and also to the process for preparing the same.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: January 26, 2021
    Assignee: AFFILOGIC
    Inventor: Olivier Kitten
  • MULTI SPECIFIC MOLECULES
    Publication number: 20200277348
    Abstract: The invention relates to proteins having multi-specific binding abilities by fusion of an OB-fold variant, in particular from the Sac7d family, to the light or heavy chain of an antibody.
    Type: Application
    Filed: November 13, 2018
    Publication date: September 3, 2020
    Inventors: Olivier KITTEN, Mathieu CINIER, Simon HUET
  • TOPICAL COMPOSITIONS COMPRISING OB-FOLD VARIANTS
    Publication number: 20200138899
    Abstract: The invention relates to a topical composition containing a variant of an OB-fold protein, and also to the process for preparing the same.
    Type: Application
    Filed: December 24, 2019
    Publication date: May 7, 2020
    Inventor: Olivier KITTEN
  • Topical compositions comprising OB-fold variants
    Patent number: 10548945
    Abstract: The invention relates to a topical composition containing a variant of an OB-fold protein, and also to the process for preparing the same.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: February 4, 2020
    Assignee: AFFILOGIC
    Inventor: Olivier Kitten
  • Oral administration compositions comprising an OB-fold protein variant
    Patent number: 10293025
    Abstract: The invention relates to an oral administration composition containing an OB-fold protein variant, and to the method for preparing the same.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: May 21, 2019
    Assignee: AFFILOGIC
    Inventor: Olivier Kitten
  • ORAL ADMINISTRATION COMPOSITIONS COMPRISING AN OB-FOLD PROTEIN VARIANT
    Publication number: 20180085427
    Abstract: The invention relates to an oral administration composition containing an OB-fold protein variant, and to the method for preparing the same.
    Type: Application
    Filed: October 23, 2015
    Publication date: March 29, 2018
    Inventor: Olivier Kitten
  • Topical Compositions Comprising OB-Fold Variants
    Publication number: 20160143990
    Abstract: The invention relates to a topical composition containing a variant of an OB-fold protein, and also to the process for preparing the same.
    Type: Application
    Filed: April 22, 2014
    Publication date: May 26, 2016
    Inventor: Olivier Kitten