Patents by Inventor Olivier Loudig

Olivier Loudig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR SMALL-RNA BIOMARKER IDENTIFICATION AND FUNCTIONAL EVALUATION OF CIRCULATING EXTRACELLULAR VESICLES COMPRISING EXOSOMES
    Publication number: 20220205990
    Abstract: A method of purifying Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV-CATCHER), designed for high-throughput analysis of low-abundance small-RNA cargos by next-generation sequencing, and use of this method for preparing purified populations of biological particles or cells from a biological sample for in vitro evaluation of a patient's risk of developing and for treating a severe viral infection; for enhancing therapeutic effectiveness of convalescent plasma therapy in a patient at risk for a severe coronavirus infection, and for treating a patient with a severe coronavirus infection, are described.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 30, 2022
    Applicant: HACKENSACK MERIDIAN HEALTH CENTER FOR DISCOVERY AND INNOVATION
    Inventors: Megan Irvette Mitchell, Olivier Loudig, Masood Kamali-Moghaddam
  • Simultaneous extraction of DNA and RNA from FFPE tissues
    Patent number: 9309559
    Abstract: The present provides methods and kits for extracting DNA and RNA from FFPE tissues and samples.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: April 12, 2016
    Assignee: Albert Einstein College of Medicine, Inc.
    Inventors: Olivier Loudig, Adam Kotorashvili, Thomas Rohan
  • SIMULTANEOUS EXTRACTION OF DNA AND RNA FROM FFPE TISSUES
    Publication number: 20140308670
    Abstract: The present provides methods and kits for extracting DNA and RNA from FFPE tissues and samples.
    Type: Application
    Filed: April 10, 2014
    Publication date: October 16, 2014
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
    Inventors: Olivier Loudig, Adam Kotorashvili, Thomas Rohan
  • Restoration of nucleic acid from degraded or formalin-fixed and paraffin-embedded tissue and uses thereof
    Patent number: 8497067
    Abstract: This invention provides methods, primers and kits for restoration of nucleic acid from tissue, in particular degraded tissue and formalin-fixed and paraffin-embedded (FFPE) tissue, where the methods involve complementary-template reverse-transcription (CT-RT) where short single-stranded DNA sequences reverse-transcribed from mRNA are used for reverse-transcription of complementary sense-RNA templates. The methods can be used to determine patterns of gene expression and chromosomal alterations in archived tissue samples, and may be used to identify expression of disease-related genes.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: July 30, 2013
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventor: Olivier Loudig
  • Restoration of Nucleic Acid From Degraded or Formalin-Fixed and Paraffin-Embedded Tissue and Uses Thereof
    Publication number: 20120009570
    Abstract: This invention provides methods, primers and kits for restoration of nucleic acid from tissue, in particular degraded tissue and formalin-fixed and paraffin-embedded (FFPE) tissue, where the methods involve complementary-template reverse-transcription (CT-RT) where short single-stranded DNA sequences reverse-transcribed from mRNA are used for reverse-transcription of complementary sense-RNA templates. The methods can be used to determine patterns of gene expression and chromosomal alterations in archived tissue samples, and may be used to identify expression of disease-related genes.
    Type: Application
    Filed: February 26, 2007
    Publication date: January 12, 2012
    Inventor: Olivier Loudig