Patents by Inventor Olivier Mirguet

Olivier Mirguet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUG OF 1,1'-(1,6-DIOXO-1,6-HEXANEDIYL)BIS-D-PROLINE
    Publication number: 20160081983
    Abstract: The present invention relates to the compound (2R,2?R)-bis(((((tetrahydro-2H-pyran-4-yl)oxy)carbonyl)oxy)methyl) 1,1?-adipoylbis(pyrrolidine-2-carboxylate), pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.
    Type: Application
    Filed: October 28, 2015
    Publication date: March 24, 2016
    Inventors: Alexis DENIS, Olivier Mirguet, Jérôme Toum
  • A PRODRUG OF 1,1'-(1,6-DIOXO-1,6-HEXANEDIYL)BIS-D-PROLINE
    Publication number: 20160075694
    Abstract: The present invention relates to the compound (2R,2?R)-bis(((((tetrahydro-2H-pyran-4-yl)oxy)carbonyl)oxy)methyl) 1,1?-adipoylbis(pyrrolidine-2-carboxylate) of formula (I), pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.
    Type: Application
    Filed: April 27, 2015
    Publication date: March 17, 2016
    Inventors: Alexis DENIS, Olivier MIRGUET, Jérôme TOUM
  • Benzodiazepine Bromodomain Inhibitor
    Publication number: 20150299210
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: June 29, 2015
    Publication date: October 22, 2015
    Inventors: James BAILEY, Romain Luc Marie GOSMINI, Olivier Mirguet, Jason Witherington
  • QUINOLINONE DERIVATIVES
    Publication number: 20150238480
    Abstract: The present invention relates to compounds of the formula (I), salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds as activators of AMPK.
    Type: Application
    Filed: May 11, 2015
    Publication date: August 27, 2015
    Inventors: Alain Claude-Marie DAUGAN, Yann LAMOTTE, Olivier MIRGUET
  • Benzodiazepine bromodomain inhibitor
    Patent number: 9102677
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: August 11, 2015
    Assignee: GlaxoSmithKline LLC
    Inventors: James Bailey, Romain Luc Marie Gosmini, Olivier Mirguet, Jason Witherington
  • Benzodiazepine Bromodomain Inhibitor
    Publication number: 20150210706
    Abstract: The present invention relates to a benzodiazepine compound, processes for its preparation, pharmaceutical compositions containing such a compound and to its use in therapy.
    Type: Application
    Filed: April 13, 2015
    Publication date: July 30, 2015
    Inventors: Romain Luc Marie GOSMINI, Olivier MIRGUET
  • Quinolinone derivatives
    Patent number: 9061998
    Abstract: The present invention relates to compounds of the formula (I), salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds as activators of AMPK.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: June 23, 2015
    Assignee: GlaxoSmithKline LLC
    Inventors: Alain Claude-Marie Daugan, Olivier Mirguet, Yann Lamotte
  • Benzodiazepine bromodomain inhibitor
    Patent number: 9023842
    Abstract: The present invention relates to a benzodiazepine compound of formula (I), processes for its preparation, pharmaceutical compositions containing such a compound and to its use in therapy.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: May 5, 2015
    Assignee: GlaxoSmithKline LLC
    Inventors: Romain Luc Marie Gosmini, Olivier Mirguet
  • QUINOLINONE DERIVATIVES
    Publication number: 20130345212
    Abstract: The present invention relates to compounds of the formula (I), salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds as activators of AMPK.
    Type: Application
    Filed: March 5, 2012
    Publication date: December 26, 2013
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Alain Claude-Marie Daugan, Olivier Mirguet, Yann Lamotte
  • 1H-PYROLLO[3,2-D]PYRIMIDINEDIONE DERIVATIVES
    Publication number: 20130345243
    Abstract: The present invention relates to pyrimidinedione compounds of formula (I), salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds of formula (I) or salts thereof as activators of AMPK.
    Type: Application
    Filed: March 5, 2012
    Publication date: December 26, 2013
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Anne Marie Jeanne Bouillot, Alain Claude-Marie Daugan, Yann Lamotte, Olivier Mirguet
  • Imidazo [4, 5-C] quinoline derivatives as bromodomain inhibitors
    Patent number: 8557984
    Abstract: Novel compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: October 15, 2013
    Assignee: GlaxoSmithKline LLC
    Inventors: Anne Marie Jeanne Bouillot, Frederic Donche, Francoise Jeanne Gellibert, Yann Lamotte, Olivier Mirguet
  • PYRROLO [3,2-D] PYRIMIDIN-3-YL DERIVATIVES USED AS ACTIVATORS OF AMPK
    Publication number: 20130053407
    Abstract: Pyrrolopyrimidones compounds of the formula (I), salts thereof, and pharmaceutical compositions containing them are disclosed herein, as well as methods for their use in medicine, for instance as activators of AMPK.
    Type: Application
    Filed: May 3, 2011
    Publication date: February 28, 2013
    Applicant: GlaxoSmithKline LLC
    Inventors: Olivier Mirguet, Anne Marie Jeanne Bouillot
  • Benzodiazepine Bromodomain Inhibitor
    Publication number: 20120252781
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: November 3, 2010
    Publication date: October 4, 2012
    Inventors: James Bailey, Romain Luc Marie Gosmini, Olivier Mirguet, Jason Witherington
  • Imidazo [4, 5-C] Quinoline Derivatives As Bromodomain Inhibitors
    Publication number: 20120232074
    Abstract: Novel compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: November 3, 2010
    Publication date: September 13, 2012
    Inventors: Anne Marie Jeanne Bouillot, Frederic Donche, Francoise Jeanne Gellibert, Yann Lamotte, Olivier Mirguet
  • Benzodiazepine Bromodomain Inhibitor
    Publication number: 20120220573
    Abstract: The present invention relates to a benzodiazepine compound of formula (I), processes for its preparation, pharmaceutical compositions containing such a compound and to its use in therapy.
    Type: Application
    Filed: August 6, 2010
    Publication date: August 30, 2012
    Inventors: Romain Luc Marie Gosmini, Olivier Mirguet
  • Condensed Azepine Derivatives As Bromodomain Inhibitors
    Publication number: 20120202799
    Abstract: Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: November 3, 2010
    Publication date: August 9, 2012
    Inventors: Miriam Crowe, Alain Claude-Marie Daugan, Romain Luc Marie Gosmini, Richard Martin Grimes, Olivier Mirguet, Jacqueline Elizabeth Mordaunt
  • PYRROLO-PYRIDINE DERIVATIVES AS ACTIVATORS OF AMPK
    Publication number: 20120172333
    Abstract: The present invention relates to pyrrolopyridone compounds of the formula (I), salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds as activators of AMPK.
    Type: Application
    Filed: September 8, 2010
    Publication date: July 5, 2012
    Applicant: GLAXOSMITHKLINE LLC
    Inventor: Olivier Mirguet