Patents by Inventor Olivier Yves Frederic Henry

Olivier Yves Frederic Henry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220412961
    Abstract: Embodiments of various aspects described herein are directed to assays and devices for detecting a target molecule in a sample. In particular, there is described a lateral assay comprising a plurality of serially oriented capture zones, where each capture zone independently comprises an immobilized competitive molecule on a lateral flow matrix. The immobilized competitive molecule and the analyte competitively bind with a capture agent capable of binding the analyte.
    Type: Application
    Filed: November 13, 2020
    Publication date: December 29, 2022
    Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Pawan JOLLY, Helena DE PUIG GUIXE, Olivier Yves Frederic HENRY, Donald E. INGBER, James J. COLLINS, Nur MUSTAFAOGLU, Nooralhuda ARKAN
  • Patent number: 11325119
    Abstract: A fluidic device includes a fluidic layer, a capture material, and an electronics layer, the fluidic layer includes a main channel and a pair of sample channels fluidly coupled to the main channel. The pair of sample channels is configured to receive and introduce a sample material into the device. The sample material includes an analyte. The capture material is positioned in a portion of the main channel that is spaced from the pair of sample channels. The capture material has a three-dimensional matrix of receptors therein configured to bond with the analyte. The capture material has a length that is associated with a dynamic range of the fluidic device and a cross-sectional area that is associated with a sensitivity of the fluidic device. The electronics layer includes electrodes configured to measure an electrical resistance through a portion of the capture material.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: May 10, 2022
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Carlos Francisco NG Pitti, Ulri Nicole Lee, Richard Novak, Olivier Yves Frederic Henry, Remco Van Erp, Donald E. Ingber
  • Publication number: 20210322976
    Abstract: A fluidic device includes a fluidic layer, a capture material, and an electronics layer, the fluidic layer includes a main channel and a pair of sample channels fluidly coupled to the main channel. The pair of sample channels is configured to receive and introduce a sample material into the device. The sample material includes an analyte. The capture material is positioned in a portion of the main channel that is spaced from the pair of sample channels. The capture material has a three-dimensional matrix of receptors therein configured to bond with the analyte. The capture material has a length that is associated with a dynamic range of the fluidic device and a cross-sectional area that is associated with a sensitivity of the fluidic device. The electronics layer includes electrodes configured to measure an electrical resistance through a portion of the capture material.
    Type: Application
    Filed: March 14, 2018
    Publication date: October 21, 2021
    Inventors: Carlos Francisco NG Pitti, Ulri Nicole Lee, Richard Novack, Olivier Yves Frederic Henry, Remco Franciscus Peter Van Erp, Donald E. Ingber
  • Publication number: 20200231822
    Abstract: Carbon nanotubes or graphene combined with proteinaceous material forming compositions that can be coated on surfaces are described. For example, the described compositions can be used as a coating on an electrode. The coatings can be functionalized with capture agents, targeting specific analytes. In addition to being conductive, the coatings prevent fouling and passivation of the electrodes by non-specific binding. This allows the coated electrodes to be used in complex matrices such as can be found in biological fluids and tissues. The coated electrodes can be regenerated and reused repeatedly.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 23, 2020
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Pawan JOLLY, Olivier Yves Frederic HENRY, Donald E. INGBER, Jonathan SABATE DEL RIO
  • Publication number: 20100075432
    Abstract: This invention relates to a sensor and in particular to a sensor for the detection of biologically important species. Specifically, the invention provides a sensor for detecting an analyte in a sample.
    Type: Application
    Filed: February 29, 2008
    Publication date: March 25, 2010
    Inventors: Sergey Anatoliyovich Piletsky, Olivier Yves Frederic Henry, Khalku Karim, Peter Georg Laitenberger