Patents by Inventor Olle Maarten DE BRUIN

Olle Maarten DE BRUIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition And Method For Stabilizing And Maintaining The Viability Of Hardy Microorganisms
    Publication number: 20230416671
    Abstract: The present application is to provide a composition and method for stabilizing and maintaining the viability of hardy microorganisms from sample collection to downstream analysis. In particular, there is a method for preserving viable hardy bacteria, such as Mycobacteria, Bacillus anthracis, or Clostridium difficile, in a biological sample, comprising contacting the biological sample with a stabilization composition, wherein the stabilization composition comprises a chelating agent, a denaturing, a salt and has a p H between about 6 and about 11.
    Type: Application
    Filed: September 12, 2023
    Publication date: December 28, 2023
    Inventors: H. Chaim Birnboim, Cassandra Kelly-Cirino, Bitapi Ray, Jacques Oscar Everard Niles, Olle Maarten de Bruin
  • Composition and method for stabilizing and maintaining the viability of hardy microorganisms
    Patent number: 11753616
    Abstract: The present application is to provide a composition and method for stabilizing and maintaining the viability of hardy microorganisms from sample collection to downstream analysis. In particular, there is a method for preserving viable hardy bacteria, such as Mycobacteria, Bacillus anthracis, or Clostridium difficile, in a biological sample, comprising contacting the biological sample with a stabilization composition, wherein the stabilization composition comprises a chelating agent, a denaturing, a salt and has a pH between about 6 and about 11.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: September 12, 2023
    Assignee: DNA Genotek, Inc.
    Inventors: H. Chaim Birnboim, Cassandra Kelly-Cirino, Bitapi Ray, Jacques Oscar Everard Niles, Olle Maarten de Bruin
  • Method and system for microbial lysis using periodates
    Patent number: 11046949
    Abstract: The present application provides a composition comprising periodates or persulfates for extracting nucleic acid from a microorganism, and a corresponding method of using the composition for nucleic acid extraction. The composition and method are particularly useful in extracting nucleic acid from microorganisms that are generally resistant to standard nucleic extraction techniques, such as, one or more species of the Mycobacterium genus, one or more species of the M. tuberculosis complex, MDR strains of M. tuberculosis, one or more species of Clostridium, one or more species of Bacillus, and other microorganisms with hardy cell walls.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: June 29, 2021
    Assignee: DNA GENOTEK INC.
    Inventors: H. Chaim Birnboim, Olle Maarten De Bruin
  • Composition And Method For Stabilizing And Maintaining The Viability Of Hardy Microorganisms
    Publication number: 20170226469
    Abstract: The present application is to provide a composition and method for stabilizing and maintaining the viability of hardy microorganisms from sample collection to downstream analysis. In particular, there is a method for preserving viable hardy bacteria, such as Mycobacteria, Bacillus anthracis, or Clostridium difficile, in a biological sample, comprising contacting the biological sample with a stabilization composition, wherein the stabilization composition comprises a chelating agent, a denaturing, a salt and has a pH between about 6 and about 11.
    Type: Application
    Filed: May 27, 2015
    Publication date: August 10, 2017
    Applicant: DNA Genotek Inc.
    Inventors: H. Chaim Birnboim, Cassandra Kelly-Cirino, Bitapi Ray, Jacques Oscar Everard Niles, Olle Maarten de Bruin
  • METHOD AND SYSTEM FOR MICROBIAL LYSIS USING PERIODATES
    Publication number: 20170130219
    Abstract: The present application provides a composition comprising periodates or persulfates for extracting nucleic acid from a microorganism, and a corresponding method of using the composition for nucleic acid extraction. The composition and method are particularly useful in extracting nucleic acid from microorganisms that are generally resistant to standard nucleic extraction techniques, such as, one or more species of the Mycobacterium genus, one or more species of the M. tuberculosis complex, MDR strains of M. tuberculosis, one or more species of Clostridium, one or more species of Bacillus, and other microorganisms with hardy cell walls.
    Type: Application
    Filed: April 10, 2015
    Publication date: May 11, 2017
    Applicant: DNA GENOTEK INC.
    Inventors: H. Chaim BIRNBOIM, Olle Maarten DE BRUIN