Patents by Inventor Olof Beck
Olof Beck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230228656Abstract: A device configured for collection and subsequent testing of a blood sample of less than 10 ml, characterized in that the container includes at least one inhibitor of the enzyme phospholipase D selected from at least one of a salt of vanadium and a salt of tungsten. A method of preparing a sample for analysis of phosphatidylethanol (PEth) comprises providing a blood sample for a patient with a volume of less than 10 ml; contacting the blood sample at least one inhibitor of the enzyme phospholipase D selected from at least one of a salt of vanadium and a salt of tungsten; and admitting inhibition of phospholipase D so formation of PEth is blocked.Type: ApplicationFiled: July 2, 2021Publication date: July 20, 2023Inventor: Olof BECK
-
Publication number: 20230228654Abstract: A device configured to collect a blood sample comprising a capillary means, wherein the capillary means is configured to collect and dry the blood sample and comprises an effective amount of a distributed inhibitor of phospholipase D. The device may be configured to receive, transport and collect a blood sample comprising a compartment in fluid connection with the capillary means, wherein the capillary means is configured to collect and dry the blood sample and comprises an effective amount of a distributed PLD inhibitor. The device may be a microfluidic device comprising an inlet portion, an outlet portion comprising a capillary means configured to collect and dry the blood sample, and optionally a metering function, wherein the microfluidic device comprises an effective amount of a distributed PLD inhibitor. The PLD inhibitor is distributed in a water soluble film, preferably a PVA film, or in an absorbent paper or polymer or in the capillary means.Type: ApplicationFiled: July 2, 2021Publication date: July 20, 2023Inventor: Olof BECK
-
Publication number: 20230125894Abstract: A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.Type: ApplicationFiled: December 23, 2022Publication date: April 27, 2023Inventors: Göran Palmskog, Olof Beck
-
Patent number: 11567011Abstract: A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.Type: GrantFiled: November 8, 2019Date of Patent: January 31, 2023Assignee: Sensa Bues ABInventors: Göran Palmskog, Olof Beck
-
Publication number: 20200109630Abstract: A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.Type: ApplicationFiled: November 8, 2019Publication date: April 9, 2020Inventors: Göran Palmskog, Olof Beck
-
Patent number: 10520439Abstract: A portable system (10) is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit (14) and a housing (12) arranged to hold the sampling unit (14), the sampling unit (14) is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing (12) has at least one inlet (15) for the subject to exhale into the housing (12) to the sampling unit (14) and at least one outlet (16) for the exhaled breath to exit through.Type: GrantFiled: September 9, 2010Date of Patent: December 31, 2019Assignee: Sensa Bues ABInventors: Göran Palmskog, Olof Beck
-
Patent number: 10359417Abstract: A portable method and sampling device for collecting aerosols comprising biomarkers from exhaled breath of a subject for further sensor based analysis. The sampling device (41) comprising a housing (406) comprising at least one inlet (407) and at least one outlet (408) for the exhaled breath to exit through, and a sampling membrane arranged in the housing. The sampling membrane is arranged to collect the aerosols from said exhaled breath.Type: GrantFiled: March 8, 2013Date of Patent: July 23, 2019Assignee: Sensa Bues ABInventors: Bo Hammarlund, Olof Beck
-
Patent number: 10220389Abstract: A microfluidic device comprises an inlet port for liquid, and a capillary channel in fluid connection to the inlet port for receiving liquid from the inlet port, the channel having a defined volume. At least one dissolvable valve is provided comprising a dissolvable membrane having a first side oriented towards the capillary channel, and a capillary connected to the second side of the dissolvable membrane such that when the membrane is dissolved by the liquid, liquid is transported through the valve to the second side of the membrane by capillary action. A method of controlling a flow of liquid uses such a microfluidic device.Type: GrantFiled: September 30, 2014Date of Patent: March 5, 2019Assignee: CAPITAINER ABInventors: Göran Stemme, Gabriel Lenk, Olof Beck, Niclas Roxhed
-
Publication number: 20180306775Abstract: A portable drug testing device for handheldly collecting a sample from exhaled breath of a subject for further sensor based analysis. The portable drug testing device comprising a housing comprising at least one inlet and at least one outlet for the exhaled breath to exit through, and a sampling membrane arranged in the housing. a tubular element having a mouthpiece section for the subject to exhale into, and a selective trap section in fluid communication with the mouthpiece and the inlet of the housing having a non-straight gas flow path for letting aerosols pass through the tubular element. The sampling membrane is arranged to collect the aerosols from the exhaled breath. The portable drug testing device further comprises a volume measure unit for determining that a pre-defined volume of the exhaled breath has passed through the sampling membrane.Type: ApplicationFiled: April 18, 2018Publication date: October 25, 2018Inventors: Olof Beck, Bo Hammarlund
-
Publication number: 20160279634Abstract: The invention relates to a microfluidic device comprising an inlet port for liquid, a capillary channel in fluid connection to the inlet port for receiving liquid from the inlet port, the channel having a defined volume. At least one dissolvable valve is provided comprising a dissolvable membrane having a first side oriented towards the capillary channel, and capillary means connected to the second side of the dissolvable membrane such that when the membrane is dissolved by the liquid, liquid is transported through the valve to the second side of the membrane by capillary action. The invention relates to uses of the device, methods of fabricating the device and method of controlling a flow of liquid.Type: ApplicationFiled: September 30, 2014Publication date: September 29, 2016Inventors: Göran STEMME, Gabriel LENK, Olof BECK, Niclas ROXHED
-
Patent number: 9429564Abstract: A method recovering one or more nonvolatile compounds from an exhaled aerosol collected on an electrostatic filter membrane (205) comprises eluting the nonvolatile compounds from the filter with a polar solvent and collecting the eluate. The method is useful for processing samples collected from a portable breath analysis device comprising a sampling filter membrane for analysis.Type: GrantFiled: September 11, 2013Date of Patent: August 30, 2016Assignee: Sensa Bues ABInventor: Olof Beck
-
Publication number: 20150226726Abstract: A method recovering one or more nonvolatile compounds from an exhaled aerosol collected on an electrostatic filter membrane (205) comprises eluting the nonvolatile compounds from the filter with a polar solvent and collecting the eluate. The method is useful for processing samples collected from a portable breath analysis device comprising a sampling filter membrane for analysis.Type: ApplicationFiled: September 11, 2013Publication date: August 13, 2015Inventor: Olof Beck
-
Publication number: 20150033824Abstract: A portable method and sampling device for collecting aerosols comprising biomarkers from exhaled breath of a subject for further sensor based analysis. The sampling device (41) comprising a housing (406) comprising at least one inlet (407) and at least one outlet (408) for the exhaled breath to exit through, and a sampling membrane arranged in the housing. The sampling membrane is arranged to collect the aerosols from said exhaled breath.Type: ApplicationFiled: March 8, 2013Publication date: February 5, 2015Inventors: Bo Hammarlund, Olof Beck
-
Publication number: 20140204374Abstract: A device, system, and methods are disclosed for detecting the presence or determining a quantitative amount of at least one drug substance from exhaled breath of a subject in-situ. A collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer that comprises at least one SERS-active material. The collecting surface is arranged as an outer surface of a waveguide for contact with exhaled breath, such that at least traces of said at least one drug substance in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum that is detected in-situ for said detecting the presence or determining the quantitative amount of said at least one drug substance from said exhaled breath.Type: ApplicationFiled: March 24, 2014Publication date: July 24, 2014Applicant: Sensa Bues ABInventors: Göran Palmskog, Olof Beck, Per Ola Andersson
-
Patent number: 8705029Abstract: A device, system, and methods are disclosed for detecting the presence or determining a quantitative amount of at least one drug substance from exhaled breath of a subject in-situ. A collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer that comprises at least one SERS-active material. The collecting surface is arranged as an outer surface of a waveguide for contact with exhaled breath, such that at least traces of said at least one drug substance in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum that is detected in-situ for said detecting the presence or determining the quantitative amount of said at least one drug substance from said exhaled breath.Type: GrantFiled: January 11, 2013Date of Patent: April 22, 2014Assignee: Sensa Bues ABInventors: Göran Palmskog, Olof Beck, Per Ola Andersson
-
Publication number: 20130066223Abstract: A drug interlock for vehicles based on exhaled breath directed onto said SERS-active substrate, wherein a detected drug substance in exhaled breath of a subject locks said vehicle from use for at least a pre-determined time or a repeated exhaled breath test where no drugs are detected. A collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer that comprises at least one SERS-active material. The collecting surface is arranged as an outer surface of a waveguide for contact with exhaled breath, such that at least traces of said at least one drug substance in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum that is detected in-situ for said detecting the presence or determining the quantitative amount of said at least one drug substance from said exhaled breath.Type: ApplicationFiled: March 9, 2012Publication date: March 14, 2013Applicant: SENSA BUES ABInventors: Olof Beck, Bo Hammarlund
-
Patent number: 8368883Abstract: A sensor for detecting a drug substance (15) from exhaled breath of a subject in-situ. Its collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer (14) of a SERS-active material. The collecting surface is arranged as an outer surface of a waveguide (12) for contact with exhaled breath, such that at least traces of said drug substance (15) in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum.Type: GrantFiled: September 9, 2010Date of Patent: February 5, 2013Assignee: Sensa Bues ABInventors: Göran Palmskog, Olof Beck, Per Ola Andersson
-
Publication number: 20120302907Abstract: A portable system (10) is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit (14) and a housing (12) arranged to hold the sampling unit (14), the sampling unit (14) is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing (12) has at least one inlet (15) for the subject to exhale into the housing (12) to the sampling unit (14) and at least one outlet (16) for the exhaled breath to exit through.Type: ApplicationFiled: September 9, 2010Publication date: November 29, 2012Applicant: SENSA BUES ABInventors: Göran Palmskog, Olof Beck
-
Publication number: 20120212735Abstract: A sensor for detecting a drug substance (15) from exhaled breath of a subject in-situ. Its collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer (14) of a SERS-active material. The collecting surface is arranged as an outer surface of a waveguide (12) for contact with exhaled breath, such that at least traces of said drug substance (15) in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum.Type: ApplicationFiled: September 9, 2010Publication date: August 23, 2012Applicant: SENSA BUES ABInventors: Göran Palmskog, Olof Beck, Per Ola Andersson
-
Publication number: 20070276133Abstract: Antibody specific for a 5-HTOL compound. A glucuronide with 5-hydroxytryptophol (5-HTOL) characterized in that it comprises the structure of the ?-glucuronide between the 5-hydroxy group of 5-HTOL and D-glucopyranosiduronic acid. An immunoassay and a diagnostic method utilizing the immunoassay wherein a 5-hydroxytryptophol (5-HTOL) compound is determined by the use of an antibody specific for a 5-HTOL compound is used.Type: ApplicationFiled: January 3, 2007Publication date: November 29, 2007Applicant: Axis Biochemicals ASAInventors: Ragnhild Brandt, Olof Beck, Anders Helander, Rose-Marie Jonsson, Eric Unger, Stefan Borg, Eva Akerblom