Abstract: A method for the manufacture of agar or agarose beads, the method comprising the steps of: i) providing a water phase comprising an aqueous solution of agar or agarose at a temperature above the gelling temperature of said aqueous solution; ii) providing an oil phase comprising a natural or vegetable oil at a temperature above the gelling temperature of the aqueous solution provided in step i); iii) combining the water phase provided in step i) with the oil phase provided in step ii) in a reactor, and adding an emulsifier; iv) emulsifying the mixture obtained in step iii), preferably by agitating the mixture, thereby creating an emulsion; v) performing a stepwise cooling comprising a first cooling step for cooling the emulsion obtained in step iv) to a temperature 0.1-30 degrees C.

Abstract: The invention relates to an improved process for the synthesis of (3S, 4S)-tetrahydrofuran-3-yl 4-isopropyl-6,7-dihydro-3H-imidazo[4,5-c]pyridine-5(4H)-carboxylate, and pharmaceutically acceptable salts thereof, such as the methanesulphonic acid salt.

Abstract: The invention relates to an improved process for the synthesis of (3S,4S)-tetrahydrofuran-3-yl 4-isopropyl-6,7-dihydro-3H-imidazo[4,5-c]pyridine-5(4H)-carboxylate, and pharmaceutically acceptable salts thereof, such as the methanesulphonic acid salt.

Abstract: The present invention provides a composition and method for minimizing side effects associated with alcohol consumption. The composition includes an effective amount of a calcium antagonist, an osmo regulator which increases the alcohol clearance rate, and a fatty acid binder. Particularity a preferred embodiment comprises an effective amount of magnesium, and effective amount of taurine, and an effective amount of carnitine. The method of minimizing side effects associated with alcohol consumption includes administering an effective amount of the above enumerated composition to an individual in need of such an effect. The composition may be administered in various manners and times.