Abstract: A method for performing port cleaning of an apparatus having a casing, a fluid circuit enclosed inside the casing, and a port arrangement. The method includes producing a cleaning fluid with the fluid circuit; passing the cleaning fluid through a first port via a first tube of the first port to a first circumferential space, from the first circumferential space via a bypass channel to a second circumferential space, and thereafter to a second tube of a second port; and passing the cleaning fluid from the second tube to a drain.

Abstract: A medical fluid for use in treatment of blood by renal replacement therapy, RRT, is generated in a system comprising pumps for pumping fluids from containers into a fluid channel for mixing therein. The pumps are controlled based on output signals from scales, on which the containers are arranged, to achieve a given mixing ratio between the fluids. The system may be configured by arranging a disposable arrangement on a machine comprising the pumps and the scales. The disposable arrangement may define the fluid channel and the containers, and the machine may be an RRT apparatus. The system may be operated to generate the medical fluid on-line for the RRT apparatus.

Abstract: A dialysis fluid connection method is disclosed herein. In an example, the method includes providing a double lumen tube including a first tube lumen and a second tube lumen. The method also includes providing a connector device having a first end connected to the double lumen tube. The connector device includes a first device lumen positioned and arranged to fluidly communicate with the first tube lumen and a second device lumen positioned and arranged to fluidly communicate with the second tube lumen. The method further includes enabling a filter unit to be connected to the connector device such that a first medium flowing through the first tube lumen and the first device lumen to the filter unit is different than a second medium flowing from the filter unit, through the second tube lumen and the second device lumen.

Abstract: A peritoneal dialysis system comprises a cycler including a peristaltic pump actuator, and a weigh scale; a disposable set including a peristaltic pump tube operable with the peristaltic pump actuator, a patient line in fluid communication with the peristaltic pump tube, and a heating container in operable communication with the weigh scale; and a control unit configured to cause (i) the peristaltic pump actuator to operate at a rotational speed to cause an amount of fluid to enter the heating container, (ii) weigh the amount of fluid, and (iii) determine at least one of a mass rate or volume rate for the rotational speed.

Abstract: A peritoneal dialysis (“PD”) system includes a patient line connector having a patient line recirculation cap to enable PD fluid to be recirculated through the patient line connector when sealingly capped by the patient line recirculation cap. The PD system also includes a drain line connector having a drain line recirculation cap enabling PD fluid to be recirculated through the drain line connector when sealingly capped by the drain line recirculation cap. The PD system further includes a dialysis fluid inline heater in fluid communication with a PD fluid side of at least one fixed volume chamber and a control unit configured to run a heat cleaning sequence after a PD treatment. For the heat cleaning sequence, the patient line connector is capped by the patient line recirculation cap and the drain line connector is capped by the drain line recirculation cap.

Abstract: A peritoneal dialysis (“PD”) system includes a housing; a dialysis fluid pump housed by the housing; a dual lumen patient line extending from the housing; a filter set including a final stage filter located along a first line, and which includes a second line in parallel with the first line, the first line in fluid communication with a first lumen of the dual lumen patient line, and the second line in fluid communication with a second lumen of the dual lumen patient line; a pressure sensor located within the housing and positioned so as to sense a static or substantially static PD fluid pressure in the second lumen while fresh PD fluid is pumped through the first lumen and the final stage filter; and a control unit configured to use the sensed static or substantially static pressure in a pressure control routine for the dialysis fluid pump.

Abstract: Disclosed herein is a water purification apparatus capable of being cleaned at a point of care, and methods for cleaning the water purification apparatus at the point of care. The water purification apparatus and the methods provide an efficient use of a heater for heat disinfection the water purification apparatus, e.g. by recirculating heated fluid to further heat the fluid. Several different cleaning programs are provided that may be utilized for cleaning different parts of the water purification apparatus.

Abstract: Ultrafiltration (UF) is monitored in a weight-based system for extracorporeal blood treatment. The system comprises a container holding a fluid that is pumped to or from a dialyzer by a pump. The container is intermittently refilled or drained by an adjustment arrangement during a level adjustment period (LAP). A scale measures the weight of the container. A monitoring device is operated to determine, before and after the LAP while the adjustment arrangement is deactivated and the pump is operated at a known setting, first and second values of a parameter of the pump based on a weight signal from the scale. The parameter may be flow rate or stroke volume. The monitoring device estimates a time profile for the parameter during the LAP based on the first and second values and determines the UF parameter based on the time profile.

Abstract: A connector arrangement (10) for connecting to a fluid chamber (6) of a blood treatment unit (4) for extracorporeal blood treatments. The connector arrangement (10) includes a connector device (11) with a connector body (47) comprising a port opening (43) and an interior wall (50) defining a port space (39) designed to receive a first fluid port (8A) of the fluid chamber (6). The connector device (11) also incorporates a fluid path (35a) extending from the port space (39) to a first end opening (51) of the connector device (11), and an air path (36a) extending from the port space (39) to a second end opening (52) of the connector device (11), wherein the fluid path (35a) and the air path (36a) are separate paths. Also a system (1) for extracorporeal blood treatment including the connector arrangement (10) and a method for priming the fluid chamber (6).

Abstract: A peritoneal dialysis (“PD”) system includes a dialysis fluid pump having a reusable pump body that accepts PD fluid for pumping; a dialysis fluid inline heater including a reusable heater body that accepts PD fluid for heating; a patient line connector; a drain line connector; a first reusable PD fluid line including a first connector configured to mate with the patient line connector; a second reusable PD fluid line including a second connector configured to mate with the drain line connector; and a control unit configured to run a heat cleaning (e.g., heat disinfection or heat sterilization) sequence after PD treatment, wherein the first connector of the first reusable PD fluid line is mated with the patient line connector, the second connector of the second reusable PD fluid line is mated with the drain line connector, and the dialysis fluid pump and perhaps the dialysis fluid inline heater are actuated.

Abstract: A peritoneal dialysis (“PD”) system includes a cycler having a weigh scale, a chamber for weighing by the weigh scale, a heater, a plurality of valves, a pump, and a control unit operable with the weigh scale, the heater, the plurality of valves and the pump; and a disposable set including a PD fluid container fitting within the chamber for weighing and heating, a supply line in fluid communication with the PD fluid container, a drain container fitting within the chamber for weighing, a drain line in fluid communication with the drain container, and a patient line positioned on an opposing side of the pump from the supply line and the drain lines, wherein the control unit is configured to operate the plurality of valves and the pump to pump used dialysis fluid to the drain container and fresh dialysis fluid from the PD fluid container.

Abstract: Methods and systems are provided for preparing a ready-to-use peritoneal dialysis fluid for peritoneal dialysis of a patient having a deficiency in potassium. The methods comprise mixing, immediately before administration to the patient, appropriate amounts of at least a first concentrate, a second concentrate, and a third concentrate with an appropriate amount of water to form a ready-to-use dialysis fluid. The first concentrate comprises glucose, has a pH of between 1.5 and 4, and is free of potassium ions; the second concentrate comprises a physiologically acceptable buffer and is free of potassium ions; and the third concentrate comprises the physiologically acceptable buffer and potassium ions.

Abstract: Disclosed herein is a water purification apparatus capable of being cleaned at a point of care, and methods for cleaning the water purification apparatus at the point of care. The water purification apparatus and the methods provide an efficient use of a heater for heat disinfection the water purification apparatus, e.g. by recirculating heated fluid to further heat the fluid. Several different cleaning programs are provided that may be utilized for cleaning different parts of the water purification apparatus.

Abstract: Disclosed herein is a disposable set for operation with first and second concentrate containers in fluid communication with first and second concentrate container connectors. The disposable set includes a pumping cassette comprising at least a first concentrate port and a second concentrate port. The disposable cassette also includes a first concentrate line in fluid communication with the first concentrate port and a second concentrate line in fluid communication with the second concentrate port. The first concentrate line terminates at a first concentrate line connector having a first configuration for mating with the first concentrate container connector.

Abstract: A peritoneal dialysis (“PD”) system includes a housing and a dialysis fluid pump housed by the housing. The dialysis fluid pump includes a reusable pump body that accepts PD fluid for pumping and a flush flow port. The PD system also includes a dialysis fluid heater for heating PD fluid, a container configured to accept and hold PD fluid, a condenser in fluid communication with the container, a chamber in fluid communication with the condenser and a flush flow line extending from the chamber to the flush flow port. The PD system further includes a control unit programmed to cause the dialysis fluid heater to heat PD fluid in the container to form steam or water vapor. The steam or water vapor is condensed in the condenser into distilled water collected in the chamber and provided from the chamber to the flush flow port via the flush flow line.

Abstract: A system comprises a first device and a second device which establish a fluid path between a pump in the first device and a container in the second device through a valve in the second device. A control unit in the second device selectively operates the valve to open the fluid path. The second device is configured to supply a medical fluid by use of a first fluid received from the first device on the fluid path. A control unit in the first device measures fluid pressure in the fluid path and operates to, intermittently during operation of the second device, activate the pump to pump the first fluid into the fluid path and, when the fluid pressure in the fluid path indicates that the valve is closed, deactivate the pump. The first device is operable to replenish the container without being synchronized with the second device.

Abstract: A peritoneal dialysis system includes a water purifier; a disposable set including a water line in fluid communication with the water purifier, a drain line for draining from the disposable set, and a disposable container including at least one chamber, the disposable container including at least one concentrate in one of the at least one chamber, and the disposable container positioned and arranged to hold a dialysis fluid prepared by mixing water from the water purifier and the at least one concentrate; and a control unit in communication with at least one sensor, for detecting a first property of water from the water purifier and a second property of the dialysis fluid.

Abstract: A peritoneal dialysis system includes a cycler comprising a control unit and a pump actuator. The peritoneal dialysis system also includes a disposable set operable with the cycler and in fluid communication with a source of water made suitable for peritoneal dialysis (“WFPD”) and a source of concentrate. The disposable set includes a pumping cassette comprising a pump chamber configured to be actuated by the pump actuator and a mixing container. The control unit is programmed to cause (i) the pump actuator to operate the pump chamber to pump a first amount of the WFPD to the mixing container, (ii) the pump actuator to operate the pump chamber to pump a prescribed amount of concentrate from the concentrate source to the mixing container, and (iii) the pump actuator to operate the pump chamber to pump a second amount of the WFPD to the mixing container.

Abstract: A peritoneal dialysis system includes a water purifier, a cycler, and a disposable set operable with the cycler. The disposable set includes a pumping cassette including a water inlet port, a heater/mixing container in fluid communication with the pumping cassette, a water accumulator, a first water line segment, and a second water line segment. The first water line segment is in fluid communication with the water inlet port and the water accumulator. Additionally, the second water line segment is in fluid communication with the water accumulator and the water purifier.

Abstract: A method for performing port cleaning of an apparatus having a casing, a fluid circuit enclosed inside the casing, and a port arrangement. The method includes producing a cleaning fluid with the fluid circuit; passing the cleaning fluid through a first port via a first tube of the first port to a first circumferential space, from the first circumferential space via a bypass channel to a second circumferential space, and thereafter to a second tube of a second port; and passing the cleaning fluid from the second tube to a drain.