Abstract: Methods and compositions, e.g., compositions for intravenous administration, comprising dextroamphetamine and/or lisdexamfetamine for use in reversal of dexmedetomidine sedation.

Abstract: Systems and method for age-compensated monitoring of a patient experiencing administration of at least one drug having anesthetic properties are provided. In one embodiment, a system includes a plurality of sensors configured to acquire physiological data from the patient and at least one processor configured to receive the physiological data from the plurality of sensors, and determine, from the physiological data, signal markers indicative of an apparent or likely patient age. The at least one processor is also configured to at least one of scale and regulate the physiological data using at least the apparent patient age to create age-compensated data, and generate a report including the age-compensated data.

Abstract: Systems and method for age-compensated monitoring of a patient experiencing administration of at least one drug having anesthetic properties are provided. In one embodiment, a system includes a plurality of sensors configured to acquire physiological data from the patient and at least one processor configured to receive the physiological data from the plurality of sensors, and determine, from the physiological data, signal markers indicative of an apparent or likely patient age. The at least one processor is also configured to at least one of scale and regulate the physiological data using at least the apparent patient age to create age-compensated data, and generate a report including the age-compensated data.

Abstract: A system and method for monitoring a patient experiencing an administration of at least one anesthetic drug. In certain embodiments, the method includes arranging sensors configured to acquire physiological data from a patient and reviewing the physiological data from the sensors and an indication received from an input. The method also includes assembling the physiological data into sets of time-series data and determining, from the sets of time-series data, a first set of signals in a first frequency range and a second set of signals in a second frequency range, the first set of signals describing a transient oscillation signature and the second set of signals describing a target wave signature. The method further includes identifying, using the transient oscillation and target wave signatures, a degree of sedation consistent with the administration of the anesthetic drug, and generating a report indicative of the degree of sedation induced by the drug.