Patents by Inventor Om P. Goel

Om P. Goel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones
    Patent number: 4672129
    Abstract: An improved process for producing anthra[1,9-cd]-pyrazol-6(2H)-ones from 1,4-dichloro-5,8-disubstituted 9,10-anthracenediones. The process produces higher yields by using a new combination of protecting groups on the compounds which allows for easier and cleaner chromatographic resolution. The compounds produced have antibacterial, antifungal, antileukemic, and antitumor activity.
    Type: Grant
    Filed: May 5, 1986
    Date of Patent: June 9, 1987
    Assignee: Warner-Lambert Company
    Inventors: Vladimir G. Beylin, Om P. Goel, H.D. Hollis Showalter
  • Process for the production of 2,2-dimethyl-5-(2,5-xylyloxy)valeric acid
    Patent number: 4126637
    Abstract: A process is provided for the production of 2,2-dimethyl-5-(2,5-xylyloxy)valeric acid which comprises subjecting 2,2-dimethyl-5-(2,5-xylyloxy)valeraldehyde to oxidation with elemental oxygen in a three-phase reaction mixture comprising a water immiscible organic solvent for said valeraldehyde, an aqueous alkaline solution, and a noble metal catalyst.
    Type: Grant
    Filed: June 17, 1977
    Date of Patent: November 21, 1978
    Assignee: Warner-Lambert Company
    Inventors: Om P. Goel, William M. Pearlman
  • Trialkylsilyl esters of 6(substituted amino)phenyl-1,-dihydro-2-oxonicotinic acid, methods for their production and conversion to the corresponding acid chlorides
    Patent number: 3951982
    Abstract: Trialkylsilyl esters of 6-(substituted amino)phenyl-1,2-dihydro-2-oxonicotinic acid and acid addition salts thereof are disclosed. The compounds are useful intermediates in the preparation of pharmacological agents, especially antimicrobials of the penicillin or cephalosporin type. The compounds can be produced by reacting a 6-(substituted amino)phenyl-1,2-dihydro-2-oxonicotinic acid with a silylating agent and are converted to the useful corresponding acid chloride by reaction with thionyl chloride.
    Type: Grant
    Filed: November 21, 1974
    Date of Patent: April 20, 1976
    Assignee: Parke, Davis & Company
    Inventor: Om P. Goel
  • Process for the preparation of acid chlorides
    Patent number: 3946015
    Abstract: A process for the production of 6-(disubstituted amino)phenyl-1,2-dihydro-2-oxonicotinyl chloride hydrochlorides, which comprises exposing the dry, finely divided corresponding 6-(disubstituted amino)phenyl-1,2-dihydro-2-oxonicotinic acid or its hydrochloride to gaseous thionyl chloride utilizing reduced atmospheric pressures. The 6-(disubstituted amino)phenyl-1,2-dihydro-2-oxonicotinyl chloride hydrochlorides are useful as intermediates in the preparation of useful semisynthetic antibiotics.
    Type: Grant
    Filed: July 11, 1974
    Date of Patent: March 23, 1976
    Assignee: Parke, Davis & Company
    Inventor: Om P. Goel