Patents by Inventor Omar Davulcu

Omar Davulcu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for modulating AAV infection
    Patent number: 10633662
    Abstract: Compositions and methods are provided for modulating adeno-associated virus (AAV) infection. For example, compositions and methods are provided for enhancing permissiveness of a target cell to AAV infection (e.g., by increasing levels of AAVR (KIAA0319L) in the cell), for reducing permissiveness of a target cell to AAV infection (e.g., by reducing levels of AAVR in the cell), and for nucleic acid delivery (e.g., by (i) increasing permissiveness of a target cell to AAV infection, e.g., by increasing the amount of AAVR in the cell; and (ii) contacting the target cell with an AAV particle that includes a nucleic acid of interest). Also provided are screening methods and kits for practicing the methods of the disclosure.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: April 28, 2020
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Oregon Health & Science University
    Inventors: Sirika Pillay, Jan Carette, Michael Stewart Chapman, Nancy Meyer, Andreas Puschnik, Omar Davulcu
  • METHODS AND COMPOSITIONS FOR MODULATING AAV INFECTION
    Publication number: 20180327752
    Abstract: Compositions and methods are provided for modulating adeno-associated virus (AAV) infection. For example, compositions and methods are provided for enhancing permissiveness of a target cell to AAV infection (e.g., by increasing levels of AAVR (KIAA0319L) in the cell), for reducing permissiveness of a target cell to AAV infection (e.g., by reducing levels of AAVR in the cell), and for nucleic acid delivery (e.g., by (i) increasing permissiveness of a target cell to AAV infection, e.g., by increasing the amount of AAVR in the cell; and (ii) contacting the target cell with an AAV particle that includes a nucleic acid of interest). Also provided are screening methods and kits for practicing the methods of the disclosure.
    Type: Application
    Filed: November 9, 2016
    Publication date: November 15, 2018
    Inventors: Sirika Pillay, Jan Carette, Michael Stewart Chapman, Nancy Meyer, Andreas Puschnik, Omar Davulcu