Patents by Inventor Omar K. Farha

Omar K. Farha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250177951
    Abstract: A material is provided comprising a Zn-(methyltriazolate)-(oxalate) metal-organic framework (MOF) having a chemical formula of Zn(3-methyl-1H-1,2,4-triazolate)(oxalate)0.5 (Zn(mtz)(ox)0.5) and comprising oxalate groups forming oxalate layers and (mtz)Zn2(mtz) groups forming (mtz)Zn2(mtz) layers. In some embodiments, oxalate groups of adjacent oxalate layers are parallel, wherein each methyl group of each (mtz)Zn2(mtz) group is oriented in opposing directions, and wherein adjacent methyl groups of adjacent (mtz)Zn2(mtz) groups and on a same side of planes defined by the oxalate groups are oriented in opposing directions. In other embodiments, oxalate groups of adjacent oxalate layers are non-parallel, and wherein each methyl group of each (mtz)Zn2(mtz) group is oriented in the same direction. Methods of using the materials to capture CO2 are also provided. Methods for synthesizing Zn-(methyltriazolate)-(oxalate) MOFs are also provided.
    Type: Application
    Filed: November 29, 2024
    Publication date: June 5, 2025
    Inventors: Xiaoliang Wang, Omar K. Farha, Randall Q. Snurr, Maytham Alzayer
  • Publication number: 20250075238
    Abstract: Composites of metal-organic framework particles and bacterial cellulose, methods of making the composites, and methods of using the composites in the hydrolysis of organic compounds are provided. The composites, which are aerogels comprising metal-organic framework particles embedded in a bacterial cellulose nanofiber network, are fabricated using a microbial synthesis strategy in which bacterial cellulose nanofiber is biosynthesized using a cellulose-producing bacteria in a fermentation medium in which metal-organic framework particles are dispersed.
    Type: Application
    Filed: January 6, 2023
    Publication date: March 6, 2025
    Inventors: Omar K. Farha, John Xin, Kaikai Ma, Yuk Ha Cheung
  • Publication number: 20240409562
    Abstract: Multifunctional and regenerable N-chlorine based biocidal and detoxifying metal-organic frameworks are provided. Chloramine functional groups on the organic linkers of the metal-organic frameworks act as chlorine carriers. Pathogens or harmful organic compounds that come into contact with the metal-organic frameworks in the presence of water are rendered inactive by reactions with the active chlorine. The metal-organic frameworks can be incorporated into textiles used to make protective wearable articles.
    Type: Application
    Filed: September 26, 2022
    Publication date: December 12, 2024
    Inventors: Omar K. Farha, John Xin, Kaikai Ma, Timur Islamoglu, Yuk Ha Cheung
  • Patent number: 12102991
    Abstract: A series of isoreticular metal-organic frameworks composed of metal nodes connected by rigid trigonal prismatic organic linkers and having a 6,12-coordinatled alb network topology are provided. Also provided are methods of synthesizing the metal-organic frameworks and methods of using the metal-organic frameworks to catalyze the hydrolysis of organic molecules, such as nerve agents, having hydrolysable bonds.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: October 1, 2024
    Assignee: Northwestern University
    Inventors: Omar K. Farha, Zhijie Chen, Penghao Li, J. Fraser Stoddart
  • Patent number: 11666637
    Abstract: Mesoporous zirconium metal-organic frameworks (MOFs) having insulin immobilized therein and methods of using the MOFs in insulin delivery are provided. The insulin-loaded metal-organic framework molecules include a porous zirconium metal-organic framework molecule and insulin molecules within pores of the porous zirconium metal-organic framework.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: June 6, 2023
    Assignee: Northwestern University
    Inventors: Omar K. Farha, Yijing Chen, Peng Li
  • Publication number: 20230048741
    Abstract: Textile fibers at least partially coated with a coating that includes particles of metal-organic frameworks dispersed in a polymeric base are provided. Also provided are fabrics formed from the textile fibers, protective gear and articles of clothing made from the fabrics, and methods of using the fibers and fabrics to catalyze the hydrolysis of organic molecules, such as organophosphate-based nerve agents, having hydrolysable bonds.
    Type: Application
    Filed: December 2, 2020
    Publication date: February 16, 2023
    Inventors: Omar K. Farha, Zhijie Chen, Kaikai Ma, Timur Islamoglu
  • Patent number: 11530404
    Abstract: Enzyme-immobilizing MOFs and methods for their use in enzymatically catalyzed reactions are provided. The MOFs are channel-type MOFs that present a hierarchical pore structure comprising a first set of large channels sized for enzyme immobilization and a second set of smaller channels running alongside of the large channels that remain enzyme-free and allow for reactant delivery to the enzymes and product expulsion from the larger channels.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: December 20, 2022
    Assignee: Northwestern University
    Inventors: Omar K. Farha, Peng Li, Justin A. Modica, Milan Mrksich, Joseph T. Hupp
  • Publication number: 20220297100
    Abstract: A series of isoreticular metal-organic frameworks composed of metal nodes connected by rigid trigonal prismatic organic linkers and having a 6,12-coordinatled alb network topology are provided. Also provided are methods of synthesizing the metal-organic frameworks and methods of using the metal-organic frameworks to catalyze the hydrolysis of organic molecules, such as nerve agents, having hydrolysable bonds.
    Type: Application
    Filed: July 16, 2020
    Publication date: September 22, 2022
    Inventors: Omar K. Farha, Zhijie Chen, Penghao Li, J. Fraser Stoddart
  • Publication number: 20220008561
    Abstract: Metal-organic frameworks with bismuth cluster nodes (Bi-MOFs) and methods of using the Bi-MOFs as contrast agents in medical imaging systems, such as computerized tomography (CT) systems, are provided. Contrast compositions that include the Bi-MOFs in a carrier in forms suitable for administration to a patient are also provided. The Bi-MOFs include those with Bi6 nodes connected by multitopic organic linkers.
    Type: Application
    Filed: November 13, 2019
    Publication date: January 13, 2022
    Inventors: Omar K. Farha, Lin Zhang, Lee N. Robison
  • Publication number: 20210387110
    Abstract: Metal-organic framework molecules with pyrene group-containing or biphenyl group-containing linkers for use in the removal of uremic toxins from biological samples that contain such toxins are provided. Also provided are methods for using the MOFs to remove uremic toxins from biological samples. The methods include hemodialysis of blood samples from patients suffering from a uremia-related disease, such as chronic kidney failure.
    Type: Application
    Filed: October 22, 2019
    Publication date: December 16, 2021
    Inventors: Omar K. Farha, Satoshi Kato
  • Publication number: 20210106940
    Abstract: A method of adsorbing a highly reactive gas onto an adsorbent material comprising adsorbing the highly reactive gas to the adsorbent material. The absorbent material comprises at least one Lewis basic functional group, or pores of a size to hold a single molecule of the highly reactive gas, or inert moieties which are provided to the adsorbent material at the same time at the same time as the highly reactive gas, prior to adsorbing the highly reactive gas or after adsorbing the highly reactive gas, or the highly reactive gas reacts with moieties of the adsorbent material resulting in passivation of the adsorbent material. A rate of decomposition of the adsorbed highly reactive gas is lower than a rate of decomposition for the neat gas at equal volumetric loadings and equal temperatures for both the adsorbed highly reactive gas and the neat gas.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Inventors: Glenn M. TOM, Paul Wai-Man SIU, Jose ARNO, Omar K. FARHA, Ross VERPLOEGH
  • Patent number: 10940426
    Abstract: A method of adsorbing a highly reactive gas onto an adsorbent material comprising adsorbing the highly reactive gas to the adsorbent material. The adsorbent material comprises at least one Lewis basic functional group, or pores of a size to hold a single molecule of the highly reactive gas, or inert moieties which are provided to the adsorbent material at the same time at the same time as the highly reactive gas, prior to adsorbing the highly reactive gas or after adsorbing the highly reactive gas, or the highly reactive gas reacts with moieties of the adsorbent material resulting in passivation of the adsorbent material. A rate of decomposition of the adsorbed highly reactive gas is lower than a rate of decomposition for the neat gas at equal volumetric loadings and equal temperatures for both the adsorbed highly reactive gas and the neat gas.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: March 9, 2021
    Assignee: NUMAT TECHNOLOGIES, INC.
    Inventors: Glenn M. Tom, Paul Wai-Man Siu, Jose Arno, Omar K. Farha, Ross Verploegh
  • Patent number: 10898847
    Abstract: A method of adsorbing a highly reactive gas onto an adsorbent material comprising adsorbing the highly reactive gas to the adsorbent material. The adsorbent material comprises at least one Lewis basic functional group, or pores of a size to hold a single molecule of the highly reactive gas, or inert moieties which are provided to the adsorbent material at the same time at the same time as the highly reactive gas, prior to adsorbing the highly reactive gas or after adsorbing the highly reactive gas, or the highly reactive gas reacts with moieties of the adsorbent material resulting in passivation of the adsorbent material. A rate of decomposition of the adsorbed highly reactive gas is lower than a rate of decomposition for the neat gas at equal volumetric loadings and equal temperatures for both the adsorbed highly reactive gas and the neat gas.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: January 26, 2021
    Assignee: NUMAT TECHNOLOGIES, INC.
    Inventors: Glenn M. Tom, Paul Wai-Man Siu, Jose Arno, Omar K. Farha, Ross Verploegh
  • Publication number: 20210000924
    Abstract: Mesoporous zirconium metal-organic frameworks (MOFs) having insulin immobilized therein and methods of using the MOFs in insulin delivery are provided. The insulin-loaded metal-organic framework molecules include a porous zirconium metal-organic framework molecule and insulin molecules within pores of the porous zirconium metal-organic framework.
    Type: Application
    Filed: March 7, 2019
    Publication date: January 7, 2021
    Inventors: Omar K. Farha, Yijing Chen, Peng Li
  • Patent number: 10525455
    Abstract: A catalyst composition comprising (a) a manganese-containing compound and (b) a carboxylic acid functionalized metal organic framework (MOF) compound; and a process for preparing an olefin oxide compound product including reacting (a) at least one olefin compound with (b) at least one oxidant in the presence of (c) the above catalyst composition.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: January 7, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: SonBinh T. Nguyen, Joseph T. Hupp, Omar K. Farha, Sergio J. Garibay
  • Patent number: 10479758
    Abstract: Metal-organic frameworks (MOFs) having inorganic nodes that comprise an octahedral Hf6 cluster capped by eight ?3-ligands and having twelve octahedral edges, wherein the ?3-ligands are hydroxo ligands, oxo ligands or aquo ligands; and organic linkers connecting the organic nodes, the organic linkers comprising 1,3,6,8-tetrakis(p-benzoic acid)pyrene units; wherein eight of the twelve octahedral edges of the inorganic nodes are connected to the 1,3,6,8-tetrakis(p-benzoic acid)pyrene units are provided.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: November 19, 2019
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Omar K. Farha, Joseph T. Hupp, M. Hassan Beyzavi, Casey J. Stephenson, Yangyang Liu
  • Publication number: 20190152897
    Abstract: Metal-organic frameworks (MOFs) having inorganic nodes that comprise an octahedral Hf6 cluster capped by eight ?3-ligands and having twelve octahedral edges, wherein the ?3-ligands are hydroxo ligands, oxo ligands or aquo ligands; and organic linkers connecting the organic nodes, the organic linkers comprising 1,3,6,8-tetrakis(p-benzoic acid)pyrene units; wherein eight of the twelve octahedral edges of the inorganic nodes are connected to the 1,3,6,8-tetrakis(p-benzoic acid)pyrene units are provided.
    Type: Application
    Filed: January 24, 2019
    Publication date: May 23, 2019
    Inventors: Omar K. Farha, Joseph T. Hupp, M. Hassan Beyzavi, Casey J. Stephenson, Yangyang Liu
  • Patent number: 10272279
    Abstract: A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the metal-organic-framework (MOF) to the chemical warfare nerve agent and catalytically decomposing the nerve agent with the MOF.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: April 30, 2019
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Joseph T. Hupp, Omar K. Farha, Michael J. Katz, Joseph E. Mondloch
  • Publication number: 20190105598
    Abstract: A method of purifying a target fluid containing one or more impurities, the method includes providing the target fluid to a vessel having an adsorbent material located therein, where the absorbent material is a metal organic framework (MOF) or a porous organic polymer (POP), preferentially adsorbing either the target fluid or at least one of the one or more impurities on the adsorbent material, and venting the target fluid from the vessel if the impurities are preferentially adsorbed on the adsorbent material or venting the one or more impurities from the vessel if the target fluid is preferentially adsorbed on the adsorbent material.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 11, 2019
    Inventors: Jose ARNO, Mitchell Hugh WESTON, Glenn M. TOM, Omar K. FARHA
  • Publication number: 20190091620
    Abstract: A method of adsorbing a highly reactive gas onto an adsorbent material comprising adsorbing the highly reactive gas to the adsorbent material. The absorbent material comprises at least one Lewis basic functional group, or pores of a size to hold a single molecule of the highly reactive gas, or inert moieties which are provided to the adsorbent material at the same time at the same time as the highly reactive gas, prior to adsorbing the highly reactive gas or after adsorbing the highly reactive gas, or the highly reactive gas reacts with moieties of the adsorbent material resulting in passivation of the adsorbent material. A rate of decomposition of the adsorbed highly reactive gas is lower than a rate of decomposition for the neat gas at equal volumetric loadings and equal temperatures for both the adsorbed highly reactive gas and the neat gas.
    Type: Application
    Filed: September 24, 2018
    Publication date: March 28, 2019
    Inventors: Glenn M. TOM, Paul Wai-Man SIU, Jose ARNO, Omar K. FARHA, Ross VERPLOEGH