Abstract: Provided herein is a class of reversible thermal gel polymers, formulations thereof, methods for using, and methods for making said reversible thermal gel polymers. Reversible thermal gel polymers and formulations are provided having versatile chemical, physical, mechanical and/or optical properties beneficial for a range of applications including medical treatment. In some embodiments, the architecture and composition of the polymer allows for tunable selection of one or more physical properties supporting a particular application.

Abstract: Provided herein is a class of reversible thermal gel polymers, formulations thereof, methods for using, and methods for making said reversible thermal gel polymers. Reversible thermal gel polymers and formulations are provided having versatile chemical, physical, mechanical and/or optical properties beneficial for a range of applications including medical treatment. In some embodiments, the architecture and composition of the polymer allows for tunable selection of one or more physical properties supporting a particular application.

Abstract: Implantable devices disclosed herein may be configured to modulate the localized pH at an implantation site of the implantable device. By controlling, modulating, or otherwise adjusting the localized pH, various benefits can be achieved, such as controlling cell proliferation. The implantable device may include a body and one or more metallic features. Generally, the implantable device forms a galvanic cell such that a first metallic feature is configured to be preferentially oxidized to alter the localized pH environment in the vicinity of the implantable device.