Patents by Inventor Om Prakash Goel

Om Prakash Goel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-C-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Patent number: 7414156
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: August 19, 2008
    Assignee: Warner Lambert Co.
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Patent number: 7230135
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: June 12, 2007
    Assignee: Warner Lambert Company LLC
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Asymmetric synthesis of pregabalin
    Patent number: 6891059
    Abstract: This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin.
    Type: Grant
    Filed: January 11, 2001
    Date of Patent: May 10, 2005
    Assignee: Warner-Lambert Company
    Inventors: Mark Joseph Burk, Om Prakash Goel, Marvin Simon Hoekstra, Thomas Frederick Mich, Thomas Mulhern, James A. Ramsden
  • Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Patent number: 6855849
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: February 15, 2005
    Assignee: Warner-Lambert Company
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Publication number: 20040215027
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: May 10, 2004
    Publication date: October 28, 2004
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Publication number: 20040138487
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 15, 2004
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Patent number: 6750171
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: June 15, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Patent number: 6689915
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: February 10, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Publication number: 20030236433
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: April 18, 2003
    Publication date: December 25, 2003
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Patent number: 6605745
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: August 12, 2003
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Publication number: 20030073868
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: September 18, 2002
    Publication date: April 17, 2003
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Publication number: 20020143214
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: February 27, 2002
    Publication date: October 3, 2002
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Publication number: 20020087017
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: December 12, 2001
    Publication date: July 4, 2002
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Prodrugs of benzofuranylethyl carbamate NK1 antagonists
    Patent number: 6258800
    Abstract: The instant invention provides aqueous soluble prodrugs of formula (I) or a pharmaceutically acceptable salt thereof wherein R is —CH2OZ, —C(═O)OCH2OZ or Z, wherein Z is formula (a), —P(═O)(OH)2 or —C(═O)Q: n is an integer of from 0 to 3; m is an integer of from 0 to 1, of certain tachykinin antagonists (NK1 antagonists) useful in the treatment of emesis.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: July 10, 2001
    Assignee: Warner-Lambert Company
    Inventors: Michael Huai Gu Chen, Om Prakash Goel, Fred M. Hershenson, Zhijian Zhu, Oilun Helen Chan