Patents by Inventor Ondrej Kotland

Ondrej Kotland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates of oligomer of hyaluronic acid or of a salt thereof, method of preparation thereof and use thereof
    Patent number: 10023658
    Abstract: The invention relates to conjugates of hyaluronic acid oligomer according to the general formulae I, II III or IV, or a salt thereof, the method of preparation thereof and use thereof, where the oligomer is bonded to the respective substrate by its ending anomeric center via a bi-functional amino linker by means of an amino or imino bond. This type of conjugates allows releasing oligomers in their native form. The prepared systems exhibited an enhanced biological activity against selected lines of cancer cells.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: July 17, 2018
    Assignee: Contipro a.s.
    Inventors: Radovan Buffa, Ivana Basarabova, Kristina Nesporova, Tereza Ehlova, Ondrej Kotland, Petra Sedova, Leos Hromek, Vladimir Velebny
  • Conjugates of Oligomer of Hyaluronic Acid or of a Salt Thereof, Method of Preparation Thereof and Use Thereof
    Publication number: 20170015759
    Abstract: The invention relates to conjugates of hyaluronic acid oligomer according to the general formulae I, II III or IV, or a salt thereof, the method of preparation thereof and use thereof, where the oligomer is bonded to the respective substrate by its ending anomeric center via a bi-functional amino linker by means of an amino or imino bond. This type of conjugates allows releasing oligomers in their native form. The prepared systems exhibited an enhanced biological activity against selected lines of cancer cells.
    Type: Application
    Filed: March 10, 2015
    Publication date: January 19, 2017
    Inventors: Radovan Buffa, Ivana Basarabova, Kristina Nesporova, Tereza Ehlova, Ondrej Kotland, Petra Sedova, Leos Hromek, Vladimir Velebny