Patents by Inventor Onur Dur

Onur Dur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260232434
    Abstract: Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere. The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.
    Type: Application
    Filed: April 10, 2026
    Publication date: August 13, 2026
    Applicants: CARNEGIE MELLON UNIVERSITY, University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Masahiro YOSHIDA, C. Douglas BERNSTEIN, Onur DUR, Kerem PEKKAN
  • Patent number: 12465746
    Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
    Type: Grant
    Filed: December 20, 2023
    Date of Patent: November 11, 2025
    Assignee: TC1 LLC
    Inventors: Onur Dur, Kevin Bourque
  • Publication number: 20240315581
    Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.
    Type: Application
    Filed: June 5, 2024
    Publication date: September 26, 2024
    Applicant: TC1 LLC
    Inventors: Daniel I. Harjes, John Freddy Hansen, Joseph C. Stark, III, Ghazal Anvar Mauro, Eric Lee, Justin A. Callaway, Onur Dur
  • Patent number: 12029535
    Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: July 9, 2024
    Assignee: TC1 LLC
    Inventors: Daniel I. Harjes, John Freddy Hansen, Joseph C. Stark, III, Ghazal Anvar Mauro, Eric Lee, Justin A. Callaway, Onur Dur
  • Publication number: 20240189572
    Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
    Type: Application
    Filed: December 20, 2023
    Publication date: June 13, 2024
    Applicant: TC1 LLC
    Inventors: Onur Dur, Kevin Bourque
  • Patent number: 11883641
    Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
    Type: Grant
    Filed: November 8, 2022
    Date of Patent: January 30, 2024
    Assignee: TC1 LLC
    Inventors: Onur Dur, Kevin Bourque
  • Publication number: 20230363896
    Abstract: Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere. The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.
    Type: Application
    Filed: April 24, 2023
    Publication date: November 16, 2023
    Applicants: CARNEGIE MELLON UNIVERSITY, UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Masahiro YOSHIDA, C. Douglas BERNSTEIN, Onur DUR, Kerem PEKKAN
  • Patent number: 11672651
    Abstract: Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: June 13, 2023
    Assignees: CARNEGIE MELLON UNIVERSITY, UNIVERSITY OF PITTSBURGH
    Inventors: Masahiro Yoshida, C. Douglas Bernstein, Onur Dur, Kerem Pekkan
  • Publication number: 20230066175
    Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
    Type: Application
    Filed: November 8, 2022
    Publication date: March 2, 2023
    Applicant: TC1 LLC
    Inventors: Onur Dur, Kevin Bourque
  • Patent number: 11511104
    Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: November 29, 2022
    Assignee: TC1 LLC
    Inventors: Onur Dur, Kevin Bourque
  • Patent number: 11478629
    Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: October 25, 2022
    Assignee: TC1 LLC
    Inventors: Daniel I. Harjes, John Freddy Hansen, Joseph C. Stark, III, Ghazal Anvar Mauro, Eric Lee, Justin A. Callaway, Onur Dur
  • Publication number: 20210316132
    Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.
    Type: Application
    Filed: June 22, 2021
    Publication date: October 14, 2021
    Applicant: TC1 LLC
    Inventors: Daniel I. Harjes, John Freddy Hansen, Joseph C. Stark, III, Ghazal Anvar Mauro, Eric Lee, Justin A. Callaway, Onur Dur
  • Patent number: 11065436
    Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: July 20, 2021
    Assignee: TC1 LLC
    Inventors: Daniel I. Harjes, John Freddy Hansen, Joseph C. Stark, III, Ghazal Anvar Mauro, Eric Lee, Justin A. Callaway, Onur Dur
  • Publication number: 20200390949
    Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
    Type: Application
    Filed: September 1, 2020
    Publication date: December 17, 2020
    Applicant: TC1 LLC
    Inventors: Onur Dur, Kevin Bourque
  • Publication number: 20200376184
    Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Applicant: TC1 LLC
    Inventors: Daniel I. Harjes, John Freddy Hansen, Joseph C. Stark, III, Ghazal Anvar Mauro, Eric Lee, Justin A. Callaway, Onur Dur
  • Patent number: 10780209
    Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: September 22, 2020
    Assignee: TC1 LLC
    Inventors: Daniel I. Harjes, John Freddy Hansen, Joseph C. Stark, III, Ghazal Anvar Mauro, Eric Lee, Justin A. Callaway, Onur Dur
  • Patent number: 10780207
    Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: September 22, 2020
    Assignee: TC1 LLC
    Inventors: Onur Dur, Kevin Bourque
  • Patent number: 10724534
    Abstract: A blood pump includes a housing and a rotor within the housing configured to rotate along an axis. The rotor may include a hub, the hub having regions with blades and regions without blades. The regions without blades may have a constant outer diameter and may extend along at least one fourth the length of the hub. The regions with blades may have an increasing outer diameter. Blades may be disposed on a downstream end region of the hub and extend downstream of the hub. Blades may begin approximately halfway along the axial length of a motor stator located about a hub and extend downstream of the motor stator. Blades may have portions that produce axial fluid flow and radial fluid flow with improved flow characteristics.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: July 28, 2020
    Assignee: TC1 LLC
    Inventors: Yi-Ren Woo, Onur Dur, Steven H. Reichenbach
  • Publication number: 20200170790
    Abstract: Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.
    Type: Application
    Filed: February 7, 2020
    Publication date: June 4, 2020
    Applicants: CARNEGIE MELLON UNIVERSITY, UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Masahiro YOSHIDA, C. Douglas BERNSTEIN, Onur DUR, Kerem PEKKAN
  • Patent number: 10624737
    Abstract: Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: April 21, 2020
    Assignees: CARNEGIE MELLON UNIVERSITY, UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Masahiro Yoshida, C. Douglas Bernstein, Onur Dur, Kerem Pekkan