Abstract: A microfluidic device for analysing a specimen comprises a loading area for loading the specimen of interest and an analytical column. The loading area is connected on two sides to a first duct and a second duct respectively, both integrated in the microfluidic device. The microfluidic device comprises a first integrated input connected to the first duct to take the specimen into the loading area, a first integrated output connected to the second duct to discharge the rest of the specimen, once it has flown through the loading area, and a second integrated output downstream the analytical column. The first integrated output is arranged for during a first loading period of time being in circuit connected to the first integrated input so as to load the sample into the loading zone of the device while preventing loss of specimen during loading of the sample into the analytical column.

Abstract: A system for a vehicle includes a memory storing a stored driver distribution profile of a driver input parameter and a stored suspension setting corresponding to the stored driver distribution profile. The system further includes a sensor to detect a current value of the driver input parameter. The system further includes a processor communicably coupled to the memory and the sensor. The processor is configured to determine a current driver distribution profile of the driver input parameter based on the current value of the driver input parameter. The processor is configured to determine a current suspension setting based on the current driver distribution profile. The processor is configured to adjust the stored suspension setting to generate a stored adjusted suspension setting corresponding to the current suspension setting.

Abstract: Inkjet ink for forming an image on a substrate, the inkjet ink comprising a pigment P, a first block copolymer dispersant D1 for dispersing the pigment P and a second block copolymer dispersant D2 for dispersing the pigment P, and an aqueous carrier; wherein said first block copolymer dispersant D1 is different from said second block copolymer dispersant D2, wherein each block copolymer dispersant D1, D2 comprises an anchoring segment A1, A2 for anchoring to the pigment P, wherein each of the block copolymer dispersant D1, D2 additionally comprises a matrix stabilization segment M for aqueous phase stabilization of the pigment P, wherein the anchoring segment A1 of the first block copolymer dispersant D1 comprises a repeating unit R1 and the anchoring segment A2 of the second block copolymer dispersant D2 comprises a repeating unit R2, wherein the repeating unit R1 is less hydrophobic than the repeating unit R2.

Abstract: A chemical reactor implemented on a substrate is described. The chemical reactor includes at least one channel for transporting a liquid and/or gas during operation of the chemical reactor. The channel comprises pillar structures perpendicular to the bottom of the channel having a transverse section parallel to the bottom that is substantially rectangular and wherein the pillar structures are provided with a porous layer of substantially homogeneous thickness applied via electrochemical anodising.

Abstract: Inkjet ink for forming an image on a substrate includes a pigment P, a block copolymer dispersant D for dispersing the pigment P, and an aqueous carrier. The block copolymer dispersant D includes an anchoring segment A for anchoring to the pigment P, where the block copolymer dispersant additionally comprises a matrix stabilization segment M for aqueous phase stabilization of the pigment. The anchoring segment A includes a repeating unit R1 and a repeating unit R2, different from R1, where the repeating unit R1 is less hydrophobic than the repeating unit R2, the repeating unit R1 includes a (poly)alkylene oxide coupled to a terminal group via a direct bond, a —C—O—C— ether bond or a —C—O—(C?O)—N— urethane bond, and the terminal group is selected from an alkyl group, an aryl group and combinations thereof.

Abstract: An apparatus for applying torque to a body includes a base defining an inner chamber. The apparatus includes a plurality of pins supported by base and disposed in the inner chamber, the plurality of pins moveable relative to the base between engaged positions and disengaged positions. The apparatus includes a trigger actuatable to move at least one of the plurality of pins to the disengaged position.

Abstract: A method for producing a chemical reactor. The chemical reactor comprises one or more effective channels which comprise pillar structures, an input connected to one of the effective channels to allow fluid/gas into the effective channels and an output connected to one of the effective channels to remove at least one component of the liquid/gas. The method comprises obtaining an initial design of the reactor, further introducing into the initial design at least a structured area positioned adjacent to an effective channel of the one or more effective channels located at the edge of the initial design, the structured area not being fluidly connected to one of the effective channels, to obtain a further design and the production of the reactor according to the further design.

Abstract: An implantable device includes a substrate and protective cover that cooperate to define an enclosed sensor volume. A sealed enclosure is provided within the sensor volume, with an electronic component assembly (ECA) being located within the sealed enclosure. A flexible circuit board assembly (FCBA) is electrically coupled with the ECA through a wall of the sealed enclosure. At least one transducer is provided on the FCBA in contact with the substrate, and the FCBA is held apart from the enclosure via a polymeric spacer provided therebetween. An inert polymer fill is provided within the sensor volume external to the enclosure.

Abstract: A method for producing a chemical reactor, wherein the chemical reactor comprises one or more effective channels which comprise pillar structures, an input connected to one of the effective channels to allow fluid/gas into the effective channels and an output connected to one of the effective channels to remove at least one component of the liquid/gas. The method comprises obtaining an initial design of the reactor, further introducing into the initial design at least a structured area positioned adjacent to an effective channel of the one or more effective channels located at the edge of the initial design, the structured area not being fluidly connected to one of the effective channels, to obtain a further design and the production of the reactor according to the further design.

Abstract: An inkjet printing apparatus for printing on a substrate, such as a flexible packaging material, includes at least three inkjet heads including a first inkjet head, a second inkjet head, and at least one further inkjet head. At least one drying unit includes a first drying unit arranged opposite a first drying location which is located between the first and second inkjet location, the first drying unit being configured for physically removing liquid from ink applied by the first inkjet head. At least a first drum and a second drum, where the first and second inkjet locations as well as the first drying location are located on an outer surface of the first drum; and the at least one further inkjet location is located on an outer surface of the second drum.

Abstract: The present invention applies to the area of cancer diagnostics. In particular, the present invention is directed to a method for the ex vivo differential diagnosis between several cancer types in a subject based on the methylation status of the Gasdermin E (GSDME) gene. In a further aspect, the present invention relates to a method for the ex vivo differential diagnosis between several cancer types based on the methylation status of at least 2 CpG sites in the GSDME gene.

Abstract: An inkjet printing process and an ink set for forming an image on a substrate by applying a plurality of inkjet inks of the ink set on the substrate. The plurality of inkjet inks include at least a first ink and a second ink, each ink comprising: a pigment and a block copolymer dispersant for dispersing the pigment. The block copolymer dispersant includes a first block and a second block where the second block is formed using at least one monomer M2, which monomer M2 is selected from the group consisting of a methacrylate and an acrylate, and where the monomer M2 is an anchoring monomer for anchoring to the pigment.

Abstract: An apparatus for applying torque to a body includes a base defining an inner chamber. The apparatus includes a plurality of pins supported by base and disposed in the inner chamber, the plurality of pins moveable relative to the base between engaged positions and disengaged positions. The apparatus includes a trigger actuatable to move at least one of the plurality of pins to the disengaged position.

Abstract: A system for a vehicle includes a memory storing a stored driver distribution profile of a driver input parameter and a stored suspension setting corresponding to the stored driver distribution profile. The system further includes a sensor to detect a current value of the driver input parameter. The system further includes a processor communicably coupled to the memory and the sensor. The processor is configured to determine a current driver distribution profile of the driver input parameter based on the current value of the driver input parameter. The processor is configured to determine a current suspension setting based on the current driver distribution profile. The processor is configured to adjust the stored suspension setting to generate a stored adjusted suspension setting corresponding to the current suspension setting.

Abstract: Example embodiments relate to methods and apparatuses for aligning a probe for scanning probe microscopy (SPM) to the tip of a pointed sample. One embodiments includes a method for aligning an SPM probe to an apex area of a free-standing tip of a pointed sample. The method includes providing an SPM apparatus that includes the SPM probe; a sample holder; a drive mechanism; and detection, control, and representation tools for acquiring and representing an image of a surface scanned by the SPM probe. The method also includes mounting the sample on the sample holder. Further, the method includes positioning the probe tip of the SPM, determining a 2-dimensional area that includes the pointed sample, performing an SPM acquisition scan, evaluating and acquired image, and placing the SPM probe in a position where it is aligned with an apex area of the free-standing tip of the pointed sample.

Abstract: An assembly for securing a component of a damper assembly includes a press movable along an axis from a retracted position to an extended position. The assembly includes a plurality of rollers rotatably supported at an end of the press. The rollers have an outer circumferential surface that includes a middle portion extending, in cross-section, transversely to the axis and linearly between an entry portion and a top portion of the outer circumferential surface.

Abstract: A method for producing a chemical reactor device based on a fluid flow comprises obtaining a substrate with a fluid channel defined by a channel wall, in which an ordered set of silicon pillar structures is positioned in the fluid channel and electrochemically anodising at least the silicon pillar structures to make the silicon pillar structures porous at least to a certain depth. After the anodising, the substrate and pillar structures are thermally treated, the treatment being carried out at a temperature, with a duration and in an atmosphere such that any silicon oxide layer formed has a thickness of less than 20 nm. The substrate and the pillar structures are further functionalized.

Abstract: A printing method in which a primer composition, which includes at least one pigment aggregating agent, is applied to a coated substrate prior to an ink-jet printing step. The ink-jet printing step is performed using inkjet droplets having x ?m drop diameter, printed in a print resolution on the coated substrate that corresponds to a rectangular unit cell having cell dimensions of y ?m by z ?m, where a ratio of x/y is >0.60.

Abstract: The present document discloses network nodes and apparatuses deployable in network systems. The network node may be coupleable via a transmission line to the apparatus. In particular, the network node may comprise means for receiving supply power from the apparatus via the transmission line; performing a line measurement on the transmission line; and signaling to the apparatus to disconnect from the transmission line, wherein the means may be further configured to perform the line measurement on the transmission line during a period of time when the apparatus is disconnected from the transmission line. The apparatus may comprise means for providing supply power to the network node; monitoring at least one electrical parameter of the transmission line; and disconnecting the apparatus from the transmission line if a predetermined line condition or a power violation is detected such that the network node can perform a measurement on the transmission line.

Abstract: An implantable device includes a substrate and protective cover that cooperate to define an enclosed sensor volume. A sealed enclosure is provided within the sensor volume, with an electronic component assembly (ECA) being located within the sealed enclosure. A flexible circuit board assembly (FCBA) is electrically coupled with the ECA through a wall of the sealed enclosure. At least one transducer is provided on the FCBA in contact with the substrate, and the FCBA is held apart from the enclosure via a polymeric spacer provided therebetween. An inert polymer fill is provided within the sensor volume external to the enclosure.