Abstract: An apparatus includes an end effector, a shaft assembly, an instrument base, and a bailout assembly. The instrument base includes at least one input assembly capable of engaging an output assembly of a robotic arm. The bailout assembly includes an actuating body and a driving assembly. The actuating body is capable of actuating relative to instrument base from a pre-bailout position, an engaged position, and a bailout position. The driving assembly is capable of actuating from a first position toward a second position to drive the output assembly of the robotic arm out of engagement with the at least one input assembly of the instrument base in response to the actuating body actuating from the engaged position into the bailout position. The driving assembly remains in the first position while the actuating body is in the pre-bailout position.

Abstract: This disclosure relates to methods of treating interstitial lung disease by administering (1S,3S)-3-((2-methyl-6-(1-methyl-5-(((methyl(propyl)carbamoyl)oxy)methyl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid (a LPA1 antagonist).

Abstract: The invention relates to a process for producing a thermoplastic moulding compound comprising a thermoplastic copolymer A and a graft copolymer B (4), comprising: continuously drying the dewatered graft copolymer B (4) by supplying a drying gas (3) and the dewatered graft copolymer B (4), by moving the dewatered graft copolymer B (4) through the drying gas (3) and forming a fluidized bed (5), the drying gas (3) having a feed temperature TG,feed in the range from 50° C. to 160° C., and by removing dried graft copolymer B (4) and an offgas (7), wherein i. a starting temperature Tin of the fluidized bed (5) on feeding (9) of the dewatered graft copolymer B (4) is measured, ii. a finish temperature Tout of the fluidized bed (5) on removal (11) of the dried graft copolymer B (4) and/or of the offgas (7) is measured, iii. a difference ?Tact between the finish temperature Tout and the starting temperature Tin is formed and the difference ?Tact is compared with a target value ?Ttarget, and iv.

Abstract: A method for producing glass fiber nozzles, comprising the steps of: A) providing or producing a base plate comprising a first material, being chemically resistant to the glass melt and dispersion strengthened, B) printing at least one tube made of a second material being chemically resistant to the glass melt onto one side of the base plate, wherein the at least one tube each comprise at least one feedthrough, C) generating at least one passage in the base plate, the passage is connected to at least one of the at least one feedthrough in such a way that each of the at least one passage through the base plate forms a common line permeable to the glass melt, with at least one of the at least one feedthrough of an associated tube leads through the base plate and through the associated tube.

Abstract: The invention is directed to a process for producing a ABS composition comprising 30-80 wt.-% of copolymer matrix A, 19.99-60 wt.-% of ABS-copolymer B, 0-40 wt.-% of polymer C and 0.01-20 wt.-% of additives D, having the steps: a) mixing the components A, B and D and optionally C, by using an extruder comprising: a first feeding zone FZ1, a mechanical dewatering zone DZ, in which component B is mechanically dewatered, and wherein: the mechanical dewatering zone DZ comprises at least one dewatering aperture, in particular for liquid water, wherein the mechanical dewatering DZ zone comprises one or more elements made of a stainless steel material; in a second feeding zone FZ2, at least part of component A and optionally part of component D are fed, preferably in melt and/or solid form, to the extruder, in a degassing zone DG component A and/or component B are degassed, and b) removing the ABS molding composition from a discharge zone CZ of the extruder.

Abstract: Disclosed is an arrangement of an X-ray detector and a shielding element shielding X-rays (RX) for increasing the spatial resolution of the X-ray detector, wherein the X-ray detector includes at least one detector line having at least one detector element arranged along the detector line, the shielding element including one or more regions opaque to X-rays (RX) and at least one region transparent to X-rays (RX), the shielding element arranged above the receiving surface for the X-rays (RX) of the at least one detector element, and the shielding element and the at least one detector element are movable relative to each other, so that the effective receiving surface for X-rays (RX) of the at least one detector element is correspondingly variable.

Abstract: The invention relates to a method for producing vascularized biological tissue, having the steps of producing a network structure made of a plurality of interconnected filaments (11) of a support polymer, coating the network structure with a protein material, populating the coated network structure with endothelial cells (2, 2A) and tissue-forming biological cells (3), and dissolving the filaments (11) such that the vascularized tissue (1) is formed. The vascularized tissue (1) comprises cardiomyocytes, liver cells, renal cells, nerve cells, and/or pancreatic cells, for example.

Abstract: The present disclosure relates to a method of processing audio content including directivity information for at least one sound source, the directivity information comprising a first set of first directivity unit vectors representing directivity directions and associated first directivity gains. The disclosure further relates to corresponding methods of encoding and decoding audio content including directivity information for at least one sound source.

Abstract: An optical system for a virtual retina display and a gesture detection of a user of the virtual retina display. The optical system includes a projector unit, an image source, and an image processing unit. The projector unit includes a first, second, and a third light source, and a first controllable deflection unit for scanning deflection of first, second, and third light beams. The optical system further includes a second deflection unit designed to transmit the first and second scanned light beams and to deflect the third light beam into a gesture detection area of the user. The optical system further includes a deflection unit, onto which the image content is projectable and which is configured to direct the projected image content and the second light beam onto an eye of a user.

Abstract: A concept for modifying a loudspeaker signal to prevent diaphragm over-deflection, in which a diaphragm deflection signal is predicted block by block, in overlapping time blocks, on the basis of the loudspeaker signal, so as to obtain one diaphragm deflection signal block per time block, is made more efficient. In accordance with an embodiment, a temporal evaluation position is determined at which then an attenuation factor is calculated from the current diaphragm deflection signal block, with the application of which a modified current diaphragm deflection signal block is obtained, and then a modified loudspeaker signal is synthesized on the basis of the modified current diaphragm deflection signal block.

Abstract: A switchgear system may include a switchgear frame, a truck and circuit breaker mounted thereon. A drive mechanism is mounted on the switchgear frame and configured to rack the circuit breaker into a) a first connected position where the primary and secondary circuits are electrically connected, b) a second test position where the primary circuit is electrically disconnected and secondary circuit connected, and c) a third disconnected position where the primary and secondary circuits are electrically disconnected, wherein said drive mechanism comprises a drive chain and shuttle configured to engage the truck and rack and fix the circuit breaker into the first connected position.

Abstract: Disclosed herein are IC structures, packages, and devices that include III-N transistor arrangements that may reduce nonlinearity of off-state capacitance of the III-N transistors. In various aspects, III-N transistor arrangements limit the extent of access regions of the transistors, compared to conventional implementations, which may limit the depletion of the access regions. Due to the limited extent of the depletion regions of a transistor, the off-state capacitance may exhibit less variability in values across different gate-source voltages and, hence, exhibit a more linear behavior during operation.

Abstract: A switchgear system includes a switchgear frame having an interior compartment and front opening and containing therein at least one electrical switchgear component. A truck carries an electrical component and is supported for movement on the switchgear frame. A drive mechanism connects the truck and is configured to rack in the truck into an electrically connected position with the at least one electrical switchgear component, rack out the truck from the electrically connected position into an electrically disconnected position, and rotate the truck upward from its disconnected position into a rotated position to allow operator access through the front opening to the at least one electrical component.

Abstract: An electrode apparatus includes a portable amplifier and a plurality of external electrodes to be disposed proximate a patient's skin. A portable computing apparatus is operably coupled to the electrode apparatus. The portable computing apparatus is configured to monitor electrical activity from tissue of a patient using the plurality of external electrodes to generate a plurality of electrical signals over time. The portable computing apparatus is configured to perform at least one of optimizing at least one parameter of the of the implantable pacing device based on the plurality of electrical signals and determining cardiac synchrony based on the plurality of electrical signals.

Abstract: Provided herein are methods of making a training aid for detecting a biohazard, and related devices and methods of using the device, including a canine training aid. The devices are made by positioning a polymer layer in proximity and physically separated from a biological material, so that volatile organic compounds contact and bind or infuse the polymer layer. The device is made render-safe by inactivating the infused polymer layer, such as by heating to a temperature sufficient to inactivate biological agents on or in the analyte-infused polymer layer. The device can be stored in a substantially air-tight configuration for subsequent use in training, such as canine and/or or artificial detectors.

Abstract: A ground and test (G&T) device includes a test device housing having load and line conductors and a plurality of upper terminals and plurality of lower terminals carried by the test device housing and configured to engage the load and line conductors when the test device housing in installed within the compartment of the switchgear frame. A lower ground bus bar is carried by the test device housing and a plurality of grounding bars selectively connect either the upper terminals to the lower ground bus bar or connect the lower terminals to the lower ground bus bar. A ground shoe assembly is connected to the lower ground bus bar and configured to engage a grounding circuit carried by the switchgear frame.

Abstract: Provided is a vacuum assisted resin transfer molding method for producing a component, in particular a spar cap, of a rotor blade including a lightning protection system, wherein the vacuum assisted resin transfer molding method includes the steps of: a) placing) an electrically conductive beam fiber material of an electrically conductive beam, an electrically conductive fiber mat and an electrical conductor of the component in a mold arrangement electrically connecting the electrically conductive beam fiber material to the electrical conductor by means of the electrically conductive fiber mat, wherein an electrical connection between the electrical conductor and the electrically conductive fiber mat is generated, c) subjecting the mold arrangement to underpressure, d) applying an external pressure on the electrical connection from outside the mold arrangement, e) injecting resin into the underpressurized mold arrangement, and f) applying heat to the mold arrangement for curing the resin.

Abstract: The present invention relates to humanized antibodies that specifically bind to IL-1R3 or a fragment or derivative thereof or a polypeptide that contains at least a portion of said antibody that is sufficient to confer IL-1R3 binding specificity. Said antibodies inhibit IL-1R3 induced NFkB activity. They also inhibit IL-1alpha, IL-1beta, IL-33, and/or IL-36 stimulated NFkB activity. The invention further relates to use of said humanized antibody in the treatment of an IL-1R3 mediated disease such as cancer. The present invention also encompasses a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of the antibody according to the invention. The pharmaceutical composition can be used in treating a IL-1R3 mediated disease such as cancer.

Abstract: A free-standing microstructure may be formed from an engineered substrate including a first silicon layer, a second silicon layer, and an intermediate layer. The second silicon layer may include a monocrystalline silicon film. The intermediate layer may be between the first silicon layer and the second silicon layer. The intermediate layer may include a silicon- or germanium-based material having a different lattice constant than the first silicon layer or the second silicon layer. The intermediate layer of the free-standing microstructure may further include one or more voids wherein at least a portion of the silicon- or germanium-based material is absent between the first silicon layer and the second silicon layer.

Abstract: A front airbag (10) for the protection of a vehicle occupant (12) in a vehicle which is specifically a passenger airbag for the protection of a passenger, in the installed and inflated state includes a contact wall (20) facing the vehicle occupant (12) and an opposite rear wall (22) as well as a first sidewall (24) facing the vehicle center as seen by the vehicle occupant (12) and an opposite second sidewall (26). The airbag (10) further includes a limiting device which, in the inflated state of the airbag (10), prevents the first sidewall (24) from further deploying so that the airbag (10) takes a first volume. The limiting device can be influenced when the head (14) of the vehicle occupant (12) contacts the airbag (10) such that it allows the first sidewall (24) to further deploy so that the airbag (10) takes a second volume larger as compared to the first volume.