Abstract: The broadband brightfield/darkfield wafer inspection system provided receives broadband brightfield illumination information via a defect detector, which signals for initiation of darkfield illumination. The defect detector forms a two dimensional histogram of the defect data and a dual mode defect decision algorithm and post processor assess defects. Darkfield radiation is provided by two adjustable height laser beams which illuminate the surface of the wafer from approximately 6 to 39 degrees. Each laser is oriented at an azimuth angle 45 degrees from the orientation of the manhattan geometry on the wafer, and 90 degrees in azimuth from one another. Vertical angular adjustability is provided by modifying cylindrical lens position to compensate for angular mirror change by translating an adjustable mirror, positioning the illumination spot into the sensor field of view, rotating and subsequently moving the cylindrical lens.

Abstract: Filled composite compositions can be used as encapsulants, underfill materials, and potting materials in electronic and optical packages that are subjected to a wide temperature range. The composites contain a matrix and a filler composition. In a preferred embodiment, the matrix is an organic material. The filler composition contains particles of a material that have a negative coefficient of thermal expansion. The filler composition contains particles having a wide range of sizes. Furthermore, the particles exhibit a non-normal, for example, log normal or power-law, particle distribution. The non-normal size distribution of the particles enables the filler composition to be formulated at high levels into organic matrices, resulting in composites that have very low coefficient of thermal expansion to match those of the semiconductor materials in the electronic package or optical components in an optical assembly.

Abstract: The present invention provides compositions of matter comprising 29p protein having bound thereto an agent whose delivery into a eukaryotic cell is desired. The present invention also provides a monoclonal antibody which specifically binds to 29p protein. The present invention further provides methods for delivering an agent into a eukaryotic cell, and methods for causing a eukaryotic cell to secrete a desired protein in the form of a fusion protein. The present invention further provides 29p protein-containing pharmaceutical compositions. The present invention still further provides nucleic acid molecules which hybridize to at least a portion of a nucleic acid molecule encoding 29p protein. Finally, the present invention provides methods for detecting the presence of, and quantitatively determining the amount of, a 29p protein-encoding nucleic acid molecule in a sample.

Abstract: An inorganic particle, to which is bonded a cell binding component and a nucleic acid, is provided for delivery of a nucleic acid to a cell. The disclosed particle acts as a synthetic vector for achieving efficient transfection of associated nucleic acid into a cell.

Abstract: The present invention is directed to (+)-cis-sertraline hydrochloride and methods of preparation. The present invention also includes processes for making sertraline having a cis/trans ratio greater than 3:1, greater than or equal to 8:1, or between about 8:1 and about 12:1, from the Schiff base of sertralone, sertraline-1-imine.

Abstract: A method for printing and supporting a three-dimensional (3-D) object is provided. The method of printing can include dispensing a first interface material for the construction of the three-dimensional object, dispensing a second interface material to form a support structure for supporting the three-dimensional object and dispensing a third interface material which May be Used to separate the support structure from the 3-D object Disclosed also a method for producing a 3-D model containing various kinds of inserts.

Abstract: A portable apparatus for sanitizing and recovering mail and other materials is disclosed. The apparatus is employed after a known or suspected biological attack or contamination event, such as anthrax. Multiple X-ray sources penetrate mail and other materials, and destroy the biological agents. The apparatus is taken to the location of the biological problem, as opposed to shipping contaminated materials to a fixed facility for recovery. Many safety and practical advantages result from this approach to bio-terrorism or to biological contamination events. The design of this apparatus leads to a self-cleaning feature. Airflow control prevents escape of toxic biological materials into the environment.

Abstract: A multi faceted system for simulating free flight, playing games in a free flight mode, and photographing the experience in a manner which permits of the creation of a montage, in which a vertical air column is defined by a variable cylindrical walls, and in which at least a portion of the air column is moving in laminar flow mode.

Abstract: New leflunomide Form III is disclosed, along with processes for preparing it. The present invention also provides an economic process for preparing leflunomide Form II and a process for preparing leflunomide Form I from leflunomide Form III. Pharmaceutical compositions and dosage forms containing the new form and methods of using them for the treatment of rheumatoid arthritis are also disclosed.

Abstract: The present invention provides a thermal driven spit for cooking, the spit being driven by the heat supplied for the cooking.

Abstract: The present invention is directed to a system and method for tuning an optical fiber Bragg grating by using a circular mechanism which uniformly stretches the fiber along its length while at the same time preserving the minimal size for stretching.

Abstract: A system and method for determining whether a target display subsystem is compliant with a reference display subsystem is provided. A target display subsystem is selected for outputting image data. Drawing instructions are generated and applied to the target display subsystem. Image data generated by the target display subsystem, responsive to the applied drawing instructions, is periodically captured and recorded. The reference subsystem is selected, and the same drawing instructions are applied to the reference display subsystem. Image data generated by the reference display subsystem is periodically captured and recorded from the reference display subsystem. Thereafter, the captured image data from the target display subsystem and the reference display subsystem are compared to determine whether the target display subsystem is compliant with the reference display subsystem.

Abstract: A packaged die (112) for an integrated circuit (62) that eliminates the wire bonds required in the prior art, and provides integrated circuit packaging while the circuit (62) is still in a wafer format. A wafer substrate (64) on which the integrated circuits (62) have been fabricated is patterned and etched to form signal and ground vias (74, 72) through the substrate (64). A back-side ground plane (82) is deposited in contact with the ground vias (72). A protective layer (90) is formed on the top surface (76) of the substrate (64), and a protective layer (98) is formed on the bottom surface (84) of the substrate (64), where the bottom protective layer (98) fills in removed substrate material between the integrated circuits (62). Vias (106) are formed through the bottom protective layer (98), and the wafer substrate (64) is diced between the integrated circuits (62).

Abstract: A preparation of a tyrphostin including a compound of a general formula: 1

Abstract: A warhead configuration for forming a large-diameter hole through a wall of a target includes a shaped charge of explosive material presenting an annular front surface portion circumscribing an axis of the charge. The annular front surface portion exhibits a concave profile as viewed in cross-section through the axis, at least part of the concave profile being configured such that a vector projecting outward from the part normal to the annular front surface portion diverges from the axis. A liner is provided adjacent to at least part of the annular front surface portion.

Abstract: In one embodiment a thread management method identifies in a main program a set of instructions that can be dynamically activated as speculative precomputation threads. A wait/sleep operation is performed on the speculative precomputation threads between thread creation and activation, and progress of non-speculative threads is gauged through monitoring a set of global variables, allowing the speculative precomputation threads to determine its relative progress with respect to non-speculative threads.

Abstract: A process for synthesizing leflunomide from 5-methylisoxazole-4-carboxylic acid and 4-trifluoromethylaniline is provided. Further provided is the leflunomide prepared by the inventive process, which is substantially free of difficult-to-separate impurities often found in leflunomide prepared by known methods, including N-(4-trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 5-methyl-N-(4-methylphenyl)-isoxazole-4-carboxamide and N-(4-trifluoromethylphenyl)-3-methyl-isoxazole-4-carboxamide. The invention further provides pharmaceutical compositions and dosage forms containing highly pure leflunomide and methods of treating disease using the leflunomide.

Abstract: In some embodiments of the present invention, a method for designing one or more surfaces of an ophthalmic optical element for an eye suffering at least from higher order aberrations includes computing an eye model and optimizing a merit function. The eye model may be computed from data on defocus of the eye, astigmatism of the eye and the higher order aberrations. The merit function may be defined in terms of the eye model and in terms of parameters of a representation of the surfaces. The optimization of the merit function yields a set of optimized parameters which can be used to obtain a description of the surfaces. The ophthalmic optical element may be a lens for spectacles, a contact lens, an intraocular lens or a multifocal lens for spectacles. The method may also be used to design the topography of corneal tissue.

Abstract: A semiconductor device, a microelectromechanical system package and a method of making the same utilize high performance vias for vertical IC packaging. A semiconductor die of the device/package has a substrate with integrated circuitry formed on a front side of the substrate. A metal bonding pad overlies the substrate on the front side of the substrate and is electrically connected to the integrated circuitry. A solder bump is located on the metal bonding pad. An electrically conductive via extends through the substrate from the metal bonding pad to a back side of the substrate where the via forms a side wall of a via hole. A plurality of the substrates are stacked on one another with the outer end of the solder bump of one substrate fitting within the via hole of an adjacent substrate. During reflow soldering, surface tension forces of the molten solder bump self-align the substrates.

Abstract: This invention relates to putative known and unknown deoxyribonucleic acid (DNA) and amino acid sequences identified in one or more metabolic pathways that lead to dwarfism and stunting in plants and the use of these sequences in agriculture to create dwarf varieties of any plant species. This invention also relates to nucleic acids sequences and polypeptides that produce altered metabolism phenotypes in plants.