Abstract: Effective use of cyclic redundancy check (CRC) signatures is achieved where each sector of a flash management unit (FMU) has a distinct CRC signature. The CRC signatures are XORed together to create a total CRC signature for the FMU. When a host device updates a single sector of the FMU, the CRC signature for the updated single sector can be changed by removing the old CRC signature corresponding to the single sector and replacing the old CRC signature with a new CRC signature corresponding to the updated single sector. The old CRC signature is XORed from the total CRC signature and then the new CRC signature is XORed with the remaining CRC signatures to create a new total CRC signature. In so doing, data integrity is ensured.

Abstract: A storage system allocates single-level cell (SLC) blocks in its memory to act as a write buffer and/or a read buffer. When the storage system uses the SLC blocks as a read buffer, the storage system reads data from multi-level cell (MLC) blocks in the memory and stores the data in the read buffer prior to receiving a read command from a host for the data. When the storage system uses the SLC blocks as a write buffer, the storage system retains certain data in the write buffer while other data is flushed from the write buffer to MLC blocks in the memory.

Abstract: A method and apparatus for video processing on a data storage device. A chip bound architecture includes a CMOS coupled to one or more NAND die, the CMOS including one or more processors, memories, and error correction code (ECC) engines capable of processing video data. According to certain embodiments, macroblocks are correlated between two I-frames, including motion vectors to define different locations of correlated macroblocks. A P-frame may be determined from a previous I-frame and its correlated macroblocks and motion vectors, while a B-frame may be determined from two or more adjacent I-frames with concomitant macroblocks and motion vectors, as well as P-frames associated with an adjacent I-frame.

Abstract: The present disclosure describes a number of anti-TNFR2 (tumor necrosis factor receptor 2) antibodies. These antibodies are TNFR2 agonists. In certain cases, these antibodies agonize TNFR2 in an Fc independent manner. These antibodies can modulate the proliferation and/or functions of regulatory T cells and myeloid-derived suppressor cells. In certain instances, these antibodies can be used to treat diseases such as GvHD or autoimmune diseases.

Abstract: The disclosure relates to devices and methods for the treatment of edema that uses an impeller with a balloon that may be mounted on the impeller housing. The invention provides devices and methods for treatment of edema that use an indwelling catheter with an impeller to lower pressure at an outlet of a lymphatic duct and a balloon on the impeller to guide and to restrict blood flow. The balloon restricts return flow from the jugular and guides that flow into the impeller cage. By funneling the flow into the impeller cage, a rate of flow down the vessel may be increased, resulting in a lateral pressure decrease effecting the lymphatic outlet. Because the lymphatic outlet is subject to a pressure decrease, fluids in the lymphatic system drain to the outlet and into the circulatory system.

Abstract: Disclosed herein is an anti-adhesion kit comprised of: (i) a fibrinogen solution component comprising: fibrinogen at a concentration of about 5 to 25 mg/ml; and free calcium ions at a concentration ranging from 0.1 ?M to 1 mM; and (ii) a thrombin component containing thrombin. Further disclosed is an anti-adhesion kit comprised of: (i) a fibrinogen solution component containing fibrinogen at a concentration of 8% to 25% of total protein by weight, and optionally free calcium ions at a concentration ranging from 0.1 ?M to 1 mM; wherein a total protein concentration ranges from about 80 to 120 mg/ml; and (ii) a thrombin component containing thrombin. Methods of using the kits e.g., to provide anti-adhesion curable compositions are also disclosed.

Abstract: The current disclosure provides methods for reprogramming mammalian somatic cells by regulating the expression of endogenous cellular genes. Cellular reprogramming of somatic cells can be induced by activating the transcription of embryonic stem cell-associated genes (e.g., oct3/4) and suppressing the transcription of somatic cell-specific and/or cell death-associated genes. The endogenous transcription machinery can be modulated using synthetic transcription factors (activators and suppressors), to allow for faster, and more efficient nuclear reprogramming under conditions amenable for clinical and commercial applications. The current disclosure further provides cells obtained from such methods, along with therapeutic methods for using such cells for the treatment of diseases amendable to stem cell therapy, as well as kits for such uses.

Abstract: A method and apparatus for dynamic controller buffer management is disclosed. According to certain embodiments, responsive to commands received from a host, a controller may adjust one or more partitions of a controller buffer memory to adjust the size of different types of buffer memory. In some embodiments, preset buffer memory configurations may be applied to the buffer memory to adjust buffer memory allocation based on the current workload. By way of example, when sequential reads are detected, a TRAM buffer size may be increased to provide additional RLA buffers, at the expense of XRAM and/or L2P buffer size. Where operations involving SLC memory is detected, allocation of buffer memory parity buffers of XRAM may be decreased, to provide additional buffer space to L2P.

Abstract: The present disclosure relates to improved methods for generating multicellular spheroids. In embodiments, an improved method may comprise (a) providing cells capable of spheroid formation; (b) centrifuging the cells; (c) adding extracellular matrix to the cells of (b) to produce a cell suspension comprising a desired concentration of extracellular matrix; and (d) allowing at least one spheroid to form; wherein (b) is performed before (c). In embodiments, cells may be seeded on a tissue culture apparatus before extracellular matrix is added to the cells. In embodiments, spheroids may be characterized, analyzed, challenged, otherwise tested, or a combination thereof. In embodiments, cells may be seeded in a volume of media that is a fraction of a volume of media that is desired for characterization, analysis, challenging, otherwise testing, or a combination thereof.

Abstract: For example, an Access Point (AP) may be configured to transmit measurement requests to a plurality of wireless communication stations (STAs) in a Basic Service Set (BSS) of the AP; to process measurement reports from the plurality of STAs in the BSS, wherein a measurement report from a STA includes reported measurements of the STA with respect to one or more wireless communication channels; to determine a selected wireless communication channel for the BSS based on the measurement reports from the plurality of STAs in the BSS; and to trigger a channel switch to switch an operational channel of the BSS to the selected wireless communication channel.

Abstract: A data storage device includes a non-volatile memory (NVM) device and a controller coupled to the NVM device. The controller is configured to create a bad block table that tracks bad blocks of the NVM device, send the bad block table to a host memory location, and check the bad block table to determine whether a block to be read or written to is bad. The controller is further configured to request information on a bad block from the bad block table located in the host memory location, determine that the requested information is not available from the host memory location, and retrieve the requested information from a location separate from the host memory location. A sum of the times to generate a request to check the flat relink table, execute the request, and retrieve the requested information is less than a time to process a host command.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for audio-visual speech separation. A method includes: obtaining, for each frame in a stream of frames from a video in which faces of one or more speakers have been detected, a respective per-frame face embedding of the face of each speaker; processing, for each speaker, the per-frame face embeddings of the face of the speaker to generate visual features for the face of the speaker; obtaining a spectrogram of an audio soundtrack for the video; processing the spectrogram to generate an audio embedding for the audio soundtrack; combining the visual features for the one or more speakers and the audio embedding for the audio soundtrack to generate an audio-visual embedding for the video; determining a respective spectrogram mask for each of the one or more speakers; and determining a respective isolated speech spectrogram for each speaker.

Abstract: The present disclosure generally relates to efficiently relocating data within a data storage device. By implementing an error correction code (ECC) module in a complementary metal oxide semiconductor (CMOS) chip for each memory die within a memory array of a memory device, the data can be relocated more efficiently. The ECC decodes the codewords at the memory die. The metadata is then extracted from the decoded codewords and transferred to a controller of the data storage device. A flash translation layer (FTL) module at the controller then checks whether the data is valid by comparing the received metadata to FTL tables. If the metadata indicates the data is valid, then the data is relocated.

Abstract: The present invention is directed to compositions comprising hydrolase-secreting bacteria and fermenting microorganisms and use thereof, such as for fermentative production of ethanol.

Abstract: Described herein are engineered anti-IL-2 antibodies with modified amino acid sequences. The engineered antibodies would confer modified receptor binding specificity to an IL-2-anti-IL2 antibody complex, inhibiting the binding of IL-2 to CD25. The engineered anti-IL-2 antibodies would facilitate expansion of subsets of effector immune cells and decrease undesirable effects caused by IL-2. Thus, the engineered anti-IL-2 antibodies would be useful in treating disease such as cancer and infection.

Abstract: The present disclosure generally relates to efficient data transfer management of zone-append commands for a zoned namespace (ZNS). The ZNS storage device comprises a memory device having a plurality of memory dies, and a controller coupled to the memory device The controller receives a plurality of zone append commands, each zone append command being associated with a zone identification identifying a zone of a plurality of zones, and fetches and aggregates data associated with each zone append command by the zone identification in an append write buffer. The aggregated data is written to the memory device upon the aggregated data for each zone reaching a predetermined programming chunk size, or to a temporary buffer if the predetermined write size is not met. Each zone uses a separate channel when sending the aggregated data for programming to the memory device, allowing multiple channels to be utilized in parallel.

Abstract: A method and apparatus for video processing on a data storage device. A chip bound architecture includes a CMOS coupled to one or more NAND die, the CMOS including one or more processors, memories, and error correction code (ECC) engines capable of processing video data. According to certain embodiments, macroblocks are correlated between two I-frames, including motion vectors to define different locations of correlated macroblocks. A P-frame may be determined from a previous I-frame and its correlated macroblocks and motion vectors, while a B-frame may be determined from two or more adjacent I-frames with concomitant macroblocks and motion vectors, as well as P-frames associated with an adjacent I-frame.

Abstract: Disclosed herein is an anti-adhesion kit comprised of: (i) a fibrinogen solution component comprising: fibrinogen at a concentration of about 5 to 25 mg/ml; and free calcium ions at a concentration ranging from 0.1 ?M to 1 mM; and (ii) a thrombin component containing thrombin. Further disclosed is an anti-adhesion kit comprised of: (i) a fibrinogen solution component containing fibrinogen at a concentration of 8% to 25% of total protein by weight, and optionally free calcium ions at a concentration ranging from 0.1 ?M to 1 mM; wherein a total protein concentration ranges from about 80 to 120 mg/ml; and (ii) a thrombin component containing thrombin. Methods of using the kits e.g., to provide anti-adhesion curable compositions are also disclosed.

Abstract: A semiconductor integrated circuit (IC) comprising a signal path combiner, comprising a plurality of input paths and an output path. The IC comprises a delay circuit having an input electrically connected to the output path, the delay circuit delaying an input signal by a variable delay time to output a delayed signal path. The IC may comprise a first storage circuit electrically connected to the output path and a second storage circuit electrically connected to the delayed signal path. The IC comprises a comparison circuit that compares outputs of the signal path combiner and the delayed signal, wherein the comparison circuit comprises a comparison output provided in a comparison data signal to at least one mitigation circuit.

Abstract: A method includes receiving a selection of a first change to a project in a first repository of a plurality of repositories and identifying one or more attributes of the first change to the project. The method further includes identifying a second change to the project in the plurality of repositories in view of the one or more attributes of the first change and performing an action in view of identifying the second change to the project.