Abstract: A method and system for manufacturing dosing capsules made of a cannabis-derived resin using a mold system, including using a dispensing plate having one or more reservoirs for holding a cannabis-derived resin powder, a first mold plate having one or more cavities corresponding to one or more reservoirs in the dispensing plate, and a second mold plate having one or more protrusions corresponding to one or more cavities in the first mold plate.

Abstract: The disclosure describes a distributed, pluggable architecture for an artificial reality (AR) system that enables concurrent execution and collaborative scene rendering for multiple artificial reality applications. For example, an AR system includes an image capture device configured to capture image data representative of a physical environment. The AR system also includes a head-mounted display (HMD) configured to output artificial reality content. The AR system further includes a plurality of concurrently executing artificial reality client applications. The AR system also includes a concurrent application engine configured to control rendering the artificial reality content as a common scene that include one or more objects from each of the plurality of artificial reality applications.

Abstract: An atraumatic catheter is provided. The catheter has an inflation section and a drainage section. At least one balloon is disposed in the inflation section and is offset from the central longitudinal axis of the catheter shaft. The length of the balloon in an actuated state is greater than the length of the balloon in a non-actuated state while the width of the balloon remains substantially the same in an actuated state and a non-actuated state.

Abstract: Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection.

Abstract: Movement of vehicles through an intersection relative to one another is actively coordinated. The coordination includes sharing data among the vehicles using Vehicle-to-Everything messaging technology. The shared data is used to sequence the movement of the vehicles through the intersection.

Abstract: Methods and systems for evaluating the biomechanical properties of a subject's spine for the purpose of optimizing a potential surgical intervention by selecting or designing surgical hardware fora spinal correction procedure. The system uses a simulated dynamic analysis configured to analyze, predict and improve the outcome of the surgical procedure by taking into account physiological, biomechanical, and anatomical factors. Machine learning algorithms use the computed distribution of forces and moments on the subject's spine, and compare the subject's results with those of patients from a reference population.

Abstract: Methods and compositions for treating a cutaneous wound to treat or limit development of a pathogenic bacterial infection are provided, involving administering to a subject having a cutaneous wound an amount effective of Corynebacteria spp., or a disclosed, composition, to treat or limit development of pathogenic bacterial infection of the wound.

Abstract: Cameras capture time-stamped images of predefined areas. Individuals and item are tracked in the images. A time-series set of images are processed to determine actions taken by the individuals with respect to the items or to determine relationships between the individuals to the items.

Abstract: Compounds capable of binding to granzyme B and comprising a radioactive moiety, for examples, compounds of Formula (I), and pharmaceutical compositions comprising such. Also provided herein are uses of the compounds and pharmaceutical composition in cancer treatment and/or imaging.

Abstract: Systems and methods are provided that may facilitate the irrigation of an anatomic space. The irrigation system can include a tube manifold, a fluid reservoir, a waste fluid trap and an emulsification system. The emulsification system can be arranged at a distal end portion of the tube manifold and can be configured to be inserted into an anatomic space and emulsify organic material located within the anatomic space.

Abstract: An electrified vehicle charging station according to an exemplary aspect of the present disclosure includes, among other things, a charger assembly including a plug connected to a terminal via a charger cable, and a transceiver configured to communicate information to an electrified vehicle which is useable to guide the electrified vehicle to an acceptable parking position. The acceptable parking position is a position in which the plug will reach a charging port of the electrified vehicle. A method is also disclosed.

Abstract: Methods and systems are provided for communicating operating conditions and operational limitations of an electric coupler that is external of a vehicle to the vehicle. In one example, functionality of a proximity detection circuit is enhanced to double as a serial communications link between a vehicle and an electric coupler.

Abstract: Compounds capable of binding to granzyme B and comprising a radioactive moiety, for examples, compounds of Formula (I), and pharmaceutical compositions comprising such. Also provided herein are uses of the compounds and pharmaceutical composition in cancer treatment, and kits and methods for cancer therapy.

Abstract: Described herein is a method for diagnosing cancer in a subject, the method comprising determining methylation status at a plurality of CpG sites within a region of a RAD9 gene in DNA present in a urine sample from the subject, wherein an amount of methylation of the plurality of CpG sites that exceeds a threshold indicates that the subject has cancer. Also described are methods of treatment, methods of assessing a methylation status of DNA present in a urine sample obtained from a human subject, methods of detecting methylation or unmethylation of a RAD9 DNA molecule of a human subject, kits, nucleic acid primers, and compositions.

Abstract: An electrified vehicle includes a synchronous switching DC/DC voltage converter, switches configured to selectively connect external charging terminals to a traction battery, the voltage converter, and external load terminals, and at least one controller programmed to operate the voltage converter and control the switches to connect the external charging terminals to the voltage converter and the external load terminals based on nominal voltage of the traction battery relative to voltage at the external charging terminals and a requested voltage supplied to the external load terminals.

Abstract: A method of assembling a ceramic matrix composite (CMC) component is provided. The method includes assessing which portions of the CMC component require relatively high-temperature capability and which portions require at least one of strength, thickness and increased thermal conductivity, making the portions that require the relatively high temperature capability with chemical vapor infiltration (CVI), making the portions that require the at least one of strength, thickness and increased thermal conductivity with melt infiltration (MI) and combining the portions that require the relatively high temperature capability with the CVI and the portions that require the at least one of strength, thickness and increased thermal conductivity with the MI.

Abstract: An access device includes an access assembly for percutaneously accessing an anatomical space in a patient. An aspiration assembly is operable to generate negative pressure in a fluidic channel of the device. The fluidic channel places the access assembly in fluid connection with the aspiration assembly. A fluid tube has a first tube end connected to the access assembly, a second tube end connected to the aspiration assembly, and a tube body. The tube body defines a manometer tube portion spaced apart from both the first and second tube ends. The manometer tube portion acts as at least part of a manometer when the device is in a manometer mode. The manometer tube portion has adjacent first and second manometer tube ends and an inflection point substantially reversing the direction of the manometer tube portion at a location spaced apart from both the first and second manometer tube ends.

Abstract: A vehicle includes a wireless transceiver configured to communicate with an infrastructure device in a vehicle-to-everything (V2X) channel having a predetermined channel frequency, the V2X channel being divided into a plurality of subchannels; and a controller, configured to responsive to the wireless transceiver detecting a wireless signal within the frequency of the V2X channel, measure a power spectral density (PSD) gradient of the wireless signal across at least two subchannels of the V2X channel, and compare a magnitude of the PSD gradient against a predetermined gradient threshold, and responsive to verifying the magnitude of the PSD gradient of the wireless signal is greater than the gradient threshold, identify there is an interference to the V2X channel.

Abstract: Methods, apparatuses, and testing devices comprising a fluid management layer including a fluid management body, a sample port defined in the fluid management body, an assay strip encased in the fluid management body along a fluid path, a valve defined on the assay strip, and a first internal vent having a first vent inlet, a first vent outlet, and a first venting channel connecting the first vent inlet to the first vent outlet, wherein the first vent inlet is arranged at a first location in the fluid management body along the fluid path downstream of the valve, and the first vent outlet is at a second location in the fluid management body upstream of the valve.

Abstract: The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.