Abstract: An electrical toothbrush system, device, method and kit are disclosed herein. In some embodiments, the system or device or kit include a suction lumen. In some embodiments, a display-control circuitry is provided, the circuitry configured to cause the display assembly to operate in the first or second display modes according to an elapsed-time-since-most-recent-operation, as measured by the timing circuitry.

Abstract: A cleaning catheter insertable into a ventilation tube and an input module are provided, the input module coupled to the cleaning catheter and including (i) an inflation module, including an inflation chamber and a one-way air inlet valve; (ii) a flow regulator, configured to assume first and second fluid-control states; and (iii) a mechanical user control element, which is configured (a) to mechanically and non-electrically set the fluid-control states, (b) to assume first and second configurations, and (c) to mechanically and non-electrically increase pressure in an interior of an inflation chamber of the cleaning catheter during a transition of the mechanical user control element from the first configuration to the second configuration. The one-way air inlet valve is arranged to allow air to flow into the inflation chamber during a transition of the mechanical user control element from the second configuration to the first configuration.

Abstract: In some embodiments, the present invention provides a computer-implemented transportation system which can include at least the following components: a specialized computer machine, including: a non-transient memory, electronically storing particular computer executable program code; a specifically programmed computer processor of the specialized computer machine of the computer-implemented transportation system that is configured to perform at least the following operations: electronically receiving, in real-time, via a computer network, a plurality of electronic riding requests from a plurality of electronic computing devices operated by a plurality of ride-sharing requesting passengers; where each electronic riding request from each ride-sharing requesting passenger includes: a passenger-requested origin point, and a passenger-requested destination point; for a particular electronic riding request, dynamically determining, in real-time, from a plurality of candidate vehicles an assigned vehicle for picking

Abstract: The invention concerns the use of compounds of formula (I) R-N1-spermidine, or 1,4-butandiamine,N-(3-amino propyl)-N1—R, (I) H2N—(CH2)3—N1 (R)—(CH2)4—NH2, as such or in the form of pharmaceutically acceptable derivatives, as the active principle in a pharmaceutical or cosmetic composition to preserve and protect epithelial stem cells, and progenitor cells that derive from them, through topical application on the skin or through the use of compounds in cell cultures. Hence, the invention especially concerns the use of compounds of formula (I) to treat cicatricial alopecia, and to stimulate and accelerate tissue repair and healing of both wounds and epidermal scars.

Abstract: Technologies are generally described for an aggregation of bandwidth from multiple wireless devices. In some examples, a source device may communicate with a destination device at a first bandwidth. The source device may divide data into a first piece and a second piece. The source device may transmit the first piece to a first wireless device and the second piece to a second wireless device over a first network. The first wireless device and second wireless device may communicate with the destination device at a second bandwidth and a third bandwidth respectively. The first bandwidth may be less than an aggregation of the second bandwidth and the third bandwidth. The first wireless device may transmit the first piece over a second network, different from the first network, to the destination device. The second wireless device may transmit the second piece over a third network, different from the first network, to the destination device.

Abstract: The present invention relates to compounds having general formula (I): CH3—(CH?CH)n—R??(I) where: n=3, 5, 7; R is chosen from —CH2—O—CO—R?, —CO—OR? or —CO—O(?), R? is chosen from H, C1-C22 alkyl or alkenyl, aryl or aralkyl, or sugars; and their pharmaceutically acceptable salts, such as sodium, potassium and lysine salts, for use as the active ingredient in pharmaceutical or cosmetic compositions for improving the pigmentation of the human skin, treating pigmentation disorders and/or improve both the photoprotective capacity of the skin and the intensity of its suntan.

Abstract: Provided herein are methods for reducing mammalian hair growth using the disclosed compounds. Also provided herein are methods of inhibiting hair growth after hair removal of an area of mammalian skin of a mammal using the disclosed compounds.

Abstract: Provided herein are methods for enhancing epidermal regeneration in a patient in need thereof, comprising topically administering to said patient a pharmaceutically acceptable composition comprising N-acetyl-3-(4-aminophenyl)-2-methoxypropionic acid or a pharmaceutically acceptable salt or stereoisomer thereof, and a pharmaceutically acceptable excipient. For example, provided are methods for treating or ameliorating cicatricial alopecia, comprising topically administering to a patient in need thereof a pharmaceutically acceptable composition comprising the disclosed compounds. Also provided are methods for protecting hair follicle progenitor cells and compositions comprising same using the disclosed compounds.

Abstract: Technologies are generally described for an aggregation of bandwidth from multiple wireless devices. In some examples, a source device may communicate with a destination device at a first bandwidth. The source device may divide data into a first piece and a second piece. The source device may transmit the first piece to a first wireless device and the second piece to a second wireless device over a first network. The first wireless device and second wireless device may communicate with the destination device at a second bandwidth and a third bandwidth respectively. The first bandwidth may be less than an aggregation of the second bandwidth and the third bandwidth. The first wireless device may transmit the first piece over a second network, different from the first network, to the destination device. The second wireless device may transmit the second piece over a third network, different from the first network, to the destination device.

Abstract: A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.

Abstract: A method for testing a signal comprises obtaining a signal, determining whether the signal has at least one period, measuring that period and providing the measurement as output. A power spectral density estimation can be used for signals having a single period, and an autocorrelation function with slicing can be used in an iterative procedure for finding multiple periods within signals.

Abstract: A method of analysis is disclosed. The method comprises: registering a target image to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image; accessing a database of registered and annotated images, and employing a polygon-wise comparison between the target image and each database image; and using the comparison for projecting annotated locations from the database images into the target image.

Abstract: The present invention relates to novel jasmonate derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as chemotherapeutic agents for prevention and treatment of cancers.

Abstract: A method for determining cell occupancy, confluency and cell migration in a cell culture, comprising receiving data related to pixel intensity in an image acquired of the cell culture, and distinguishing between cell concentrations in different locations in the cell culture by detecting variations in pixel intensity between multi pixel locations.

Abstract: Filamentous bacteriophage which does not display an antibody or a non-filamentous bacteriophage antigen on its surface is used to inhibit or treat brain inflammation associated with amyloid deposits and/or involving activated microglia, to inhibit the formation of amyloid deposits, and to disaggregate pre-formed amyloid deposits.

Abstract: Novel crystalline form of perphenazine 4-aminobutyrate trimesylate and a process of producing the same are disclosed. The novel crystalline form is characterized by a unique XRPD pattern and a DSC that exhibits an endothermic peak at a relatively high temperature (e.g., higher than 209° C.). Also disclosed are a process of preparing perphenazine 4-aminobutyrate trimesylate by in situ deprotection and salification, in a single-step synthesis, and a highly pure perphenazine 4-aminobutyrate trimesylate obtained thereby. Uses of any of the described perphenazine 4-aminobutyrate trimesylate are also disclosed.

Abstract: A method of processing an image is disclosed. The method comprises obtaining an image decomposed into a set of scaled images, each being characterized by a different image-scale; and calculating, for each of at least some scaled images, a relative luminance between the scaled image and another scaled image of the set, using intensities in the scaled image and intensities in the another scaled image. The method further comprises processing each scaled image using an adaptation procedure featuring an image-specific effective saturation function of the relative luminance, thereby providing a processed scaled image; combining at least some of the processed scaled images to provide a combined image; and outputting the combined image to a computer readable medium.

Abstract: A tunable tilting device is described. The device includes a tilting element and a suspension structure that has one or more flexures coupled to the tilting element. The suspension structure has a variable bending stiffness and configured to bend due to a tilting motion of the tilting element around a pivot axis. The suspension structure is responsive to a tuning force actuating a variation of an extension stress or a compression stress of the suspension structure, and thereby can vary the bending stiffness of the suspension structure.

Abstract: Serotonin reuptake inhibitor compounds which are designed to exert serotonin uptake inhibitory activity in the peripheral system while being devoid of CNS activity, and a process of preparing same are disclosed. Further disclosed are pharmaceutical compositions containing same and uses thereof in the treatment of medical conditions associated with peripheral serotonin levels and/or activity, and/or platelet aggregation.

Abstract: The invention provides novel compounds and pharmaceutical compositions for the treatment of psychological and/or psychiatric diseases or disorders.