Abstract: One or more preferred embodiments facilitate use of patient panomics indications to select treatments that will provide optimal results. One or more preferred embodiments relate to a practical ontology for the panomics domain that is utilized to support use of patient panomics indications. In accordance with one or more preferred implementations, a cancer panomics ontology facilitates replacement of traditional cancer stratification by organs (e.g. lung, breast, liver cancer) with cancer stratification by tumor biomarkers (e.g. HER2 mutations). In accordance with one or more preferred implementations, a panomic ontology is utilized to facilitate functionality of a precision medical system.

Abstract: Methods, apparatus, and systems for medical procedures are disclosed herein for receiving an input of a plurality of measured coordinates of a respective plurality of position transducers of a probe inside a body of a subject, receiving a measured voltage measurement output by the probe, determining a cost function based on a model of known mechanical properties of the probe compared to the measured coordinates with respect to shapes that can be assumed by the probe in the body and further based on an expected voltage value compared to the measured voltage measurement, selecting a shape based on the cost function, generating corrected coordinates of the points along the probe based on the shape and displaying a representation of the probe using the corrected coordinates.

Abstract: A treatment assembly can have an inner layer having an inner surface and an outer surface and defining a plurality of openings extending therethrough. The treatment assembly can further comprise a plurality of plates, each plate being at least partially received within a respective opening of the plurality of openings of the inner layer. The treatment assembly can further comprise treatment circuitry comprising a cable having a plurality of electrical leads and a plurality of lead ends, each electrical lead being electrically connected to a respective lead end of the plurality of lead ends. A cover layer can be attached to the outer surface of the inner layer and overlie the plurality of lead ends of the cable. The plurality of lead ends can be in contact with respective plates of the plurality of plates to define a plurality of electrodes.

Abstract: Assay systems including assay apparatus and handheld assay devices for use therewith for obtaining diagnostic information of a bodily specimen. Assay devices include a cartridge housing snugly accommodating a specimen slide intended for elevation from an initial lowermost specimen introduction position to a final uppermost specimen examination position in which a bodily specimen is compressed between a cartridge housing top face and a specimen slide. Assay devices preferably include a liquid reagent dispensing arrangement for dispensing liquid reagent on a specimen slide for reacting with a bodily specimen.

Abstract: Multi subunit protein modules are provided. Accordingly, there is provided a multi subunit protein module comprising at least three cell membrane polypeptides each comprising an amino acid sequence of an Fc receptor common gamma chain (FcRgamma), said amino acid sequence is capable of transmitting an activating signal; wherein at least one but not all of said at least three polypeptides comprises an extracellular binding domain capable of binding a target that is presented on a cell surface of a target cell of an immune cell, such that upon binding of said extracellular binding domain to said target said activating signal is transmitted in an immune cell expressing said multi subunit protein module. Also provided are cells expressing the multi subunit protein modules and uses thereof.

Abstract: Systems and methods herein are for one or more processing units to be associated with at least one switch or router of different route layers and to enable the at least one switch or router to receive a communication from a host machine, wherein the communication includes at least a data packet and a hash header, wherein the data packet is for transmission to other host machines through at least one of available egress ports of the at least one switch or router, and where the at least one of the available egress ports is determined based in part on a hash in the hash header.

Abstract: There are provided systems and methods comprising obtaining design data of each of a plurality of given overlay targets comprising a plurality of stacked layers, using at least part of the design data to simulate image data of each given overlay target that would have been acquired by an electron beam examination system, using the image data to determine, before actual manufacturing of each given overlay target, second data informative of estimated probability that each given overlay target, upon being manufactured according to the design data, provides measurement data in an overlay measurement process meeting a measurement quality criterion, and using the second data of each given overlay target to select at least one optimal overlay target among the plurality of different overlay targets, wherein the at least one optimal overlay target is usable to be actually manufactured on the semiconductor specimen.

Abstract: A system includes a plate and a vacuum source. The plate has a first surface and a second surface opposite the first surface, the plate is configured to receive on the first surface a flexible substrate including a first section having a first flexibility and a second section having a second flexibility different from the first flexibility, the plate has through-holes (TH), between the first and second surfaces, with a variable density that varies from a first pattern arranged in a first density opposite the first section to a second pattern arranged in a second density, different from the first density, opposite the second section. The vacuum source is configured to draw a vacuum in the TH between the first and second surfaces for fixing the first section to the first pattern and the second section to the second pattern.

Abstract: Provided are a computer program product, system, and method for editing a target model to forget data samples. Forget data samples of data samples to forget are inputted into a reference model, trained on a non-private data set, to produce reference output. The forget data samples to forget are inputted to a target model, trained on a total data set comprising the non-private data set and a private data set, to produce target output. The private data set includes the forget data samples A loss function is calculated to measure a divergence of the reference output and the target output. A determination is made of gradients that minimize an error of the loss function. Optimized gradients are calculated from the determined gradients. The optimized gradients are applied to update weights in the target model to produce an edited target model.

Abstract: Methods, systems, and devices for power management associated with memory and a controller are described. A memory system performs a power management operation that accounts for power usage by any combination of application specific integrated circuits (ASICs) and memory arrays. The power management operation includes multiple logical unit numbers (LUNs) assigned to a single ASIC, which increases a quantity of bits for communicating a power usage. An ASIC included in a memory system may utilize twice as many bits for communicating power usage information when compared to a NAND array. As part of the power management operation, an ASIC may transmit, to a controller, a first set of bits indicating a power usage of the ASIC, a first subset of the set of bits transmitted during a first instance of a token ring and a second subset of the set of bits transmitted during a second instance of the token ring.

Abstract: There are provided systems and methods comprising, for each given overlay target of a plurality of different overlay targets to be manufactured on a semiconductor specimen, said given overlay target comprising a plurality of stacked semiconductor layers, obtaining a design image of the given overlay target, feeding the design image to a trained machine learning model, to simulate at least one image of the given overlay target that would have been acquired by an electron beam examination system, using the at least one image to determine, before actual manufacturing of the given overlay target, data informative of at least one simulated overlay in the image, and using the data informative of the at least one simulated overlay of each given overlay target to select at least one optimal overlay target among the plurality of different overlay targets, the optimal overlay target being usable to be manufactured on the semiconductor specimen.

Abstract: A system and method for content recommendation, including: (i) a computer processor, (ii) a recaller module configured to receive a request for a secondary media item, and identify a set of candidate secondary media items associated with the source media item and (iii) a ranking module executing on the computer processor and configured to enable the computer processor to generate, based on the user identifier, a set of user vectors, a set of secondary media vectors, and a set of source media vectors, execute a machine learning model using the vectors to generate a ranking score for each of the secondary media items, wherein executing the machine learning model includes performing a contextual multi-armed bandit algorithm involving exploration and exploitation of candidate items based on historical data, and return a subset of the set of candidate secondary media items in response to the request.

Abstract: Methods, systems, and devices for command and data path error protection are described. In some examples, a memory system may receive data units from a host device. The data units may include respective sets of parity bits, and the memory system may perform an error detection operation on the data units. A first controller of the memory system may generate a protocol unit using data (e.g., a subset of data) from the data units. The protocol unit may include a set of parity bits (e.g., a different set of parity bits), and a second controller of the memory system may perform an error detection operation on the protocol unit. The second controller of the memory system may generate a data storage unit using data (e.g., a subset of data) from the protocol unit, and may store the data unit and another set of parity bits to a memory device.

Abstract: Various implementations disclosed herein include devices, systems, and methods that provide retinal imaging-based gaze tracking In some implementations, a user's gaze is tracked based on a retinal imaging technique that selectively uses a subset of multiple light sources (222, 310, 610) that illuminate different portions of the user's retina (352). In some implementations, a method (700) includes selecting (710) a subset of light sources, where the subset of the light sources includes less than all of the light sources. In some implementations, one or more portions of a retina (352) are illuminated (720) by producing light using the subset of the light sources. In some implementations, sensor data is received (730) at a sensor (224, 340, 814), the sensor data corresponding to the light detected during retinal imaging, and an eye characteristic is determined (740) based on the sensor data.

Abstract: A method, system and product comprising: obtaining a functional-level representation of a quantum circuit that comprises a functional block, wherein the functional block defines an operation of the quantum circuit over at least two cycles; selecting from a function library an implementation for the functional block, wherein the function library comprises a plurality of alternative implementations of the functional block, wherein each implementation of the plurality of alternative implementations is configured to provide a same functionality of the functional block and is applicable to a quantum computer to be used for executing the quantum circuit; and generating a gate-level representation of the quantum circuit that comprises the implementation for the functional block.

Abstract: Digital cameras comprising a lens assembly comprising N lens elements L1-LN starting with L1 on an object side, wherein N is ?4, an image sensor having a sensor diagonal SD, and a pop-out mechanism that controls a largest air-gap d between two consecutive lens elements within lens elements L1 and LN to bring the camera to an operative pop-out state and a collapsed state, wherein the lens assembly has a total track length TTL in the operative pop-out state and a collapsed total track length cTTL in the collapsed state, wherein SD is in the range of 7-20 mm and wherein cTTL/SD<0.6.

Abstract: Methods, systems, and devices for command timer interrupt are described. In some cases, a memory system having a host-driven logical block interface may maintain a timer to measure processing of commands. For example, upon receiving a command and storing the command in a command queue, a protocol controller of the memory system may issue the command to a command controller of the memory system and initiate the timer. Upon receiving a response for the command from the command controller, the protocol controller may reset or stop the timer, depending on whether the command queue is empty. If the timer expires prior to receiving a response for the command, the protocol controller may issue an interrupt signal to the command controller.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for audio-visual speech separation. A method includes: receiving, by a user device, a first indication of one or more first speakers visible in a current view recorded by a camera of the user device, in response, generating a respective isolated speech signal for each of the one or more first speakers that isolates speech of the first speaker in the current view and sending the isolated speech signals for each of the one or more first speakers to a listening device operatively coupled to the user device, receiving, by the user device, a second indication of one or more second speakers visible in the current view recorded by the camera of the user device, and in response generating and sending a respective isolated speech signal for each of the one or more second speakers to the listening device.

Abstract: A method of producing spherical particles is provided herein. Also provided are compositions generated thereby and uses thereof in disease diagnosis and treatment.