Abstract: Embodiments automatically determine code lineage. One such embodiment determines at least one component fingerprint associated with a software component and determines at least one code fingerprint associated with a codebase. In turn, correspondence between the determined at least one component fingerprint and the determined at least one code fingerprint is evaluated to determine code lineage of the software component.

Abstract: A device may include a housing configured to be worn by a user, a sensor configured to detect a safety event, and a low-power communication module configured to transmit a low-power alert signal to a nearby central. The central may be configured to transmit a higher-power signal to a remote backend in response to receiving the low-power alert signal, initiating a safety protocol, such as a notification to a nearby user of a potential safety event.

Abstract: Embodiments disclosed herein are directed to systems and processes that derive clinically meaningful data from a test device and a production device for assessing gait and speech in subjects having a neurological condition. The test device for gait analysis may be a simpler or more updated device in reference to a production device. Speech characteristics may be evaluated using a digital mobile speech-based platform. Other aspects are disclosed and claimed.

Abstract: Systems and methods for motor assessment including receiving first sensed signals in response to a first motor assessment performed using a first test device, receiving second sensed signals in response to a second motor assessment different than the first motor assessment and performed using the first test device, performing noise reduction for the first sensed signals and the second sensed signals, performing position normalization for the first sensed signals and the second sensed signals, generating transformed signals based on the noise reduction and the position normalization for the first sensed signals and the second sensed signals, extracting features based on the transformed signals, providing the extracted features to a machine learning model trained to output a motor assessment based prediction based on the transformed signals; and/or receiving the motor assessment based prediction from the machine learning model.

Abstract: The present disclosure relates to a microfluidic devices and methods for culturing bone marrow cells. Aspects include methods of preparing microfluidic devices and culturing bone marrow cells with the microfluidic devices. In some aspects, a method includes providing a microfluidic device having an upper chamber, a lower chamber, and a porous membrane separating the upper chamber from the lower chamber. The method further includes seeding walls of the lower chamber and a bottom surface of the membrane with endothelial cells. The method further includes providing a matrix within the upper chamber. The matrix includes fibrin gel and bone marrow cells. The method further includes filling or perfusing the upper chamber with a media.

Abstract: Systems and techniques disclosed herein include receiving static device data in response to detected first biometric movements, receiving mobile device data in response to detected second biometric movements, applying an analysis algorithm to the static data to determine static attributes, applying the analysis algorithm to the mobile data to determine mobile attributes, comparing the static attributes to the mobile attributes, and determining a modification action based on the comparing. A mobile device may be validated based on the determining that the static attributes are within a threshold parameter of the mobile attributes.

Abstract: The present disclosure relates to a microfluidic devices and methods for culturing bone marrow cells. Aspects include methods of preparing microfluidic devices and culturing bone marrow cells with the microfluidic devices. In some aspects, a method includes providing a microfluidic device having an upper chamber, a lower chamber, and a porous membrane separating the upper chamber from the lower chamber. The method further includes seeding walls of the lower chamber and a bottom surface of the membrane with endothelial cells. The method further includes providing a matrix within the upper chamber. The matrix includes fibrin gel and bone marrow cells. The method further includes filling or perfusing the upper chamber with a media.

Abstract: The present disclosure relates to a microfluidic devices and methods for culturing bone marrow cells. Aspects include methods of preparing microfluidic devices and culturing bone marrow cells with the microfluidic devices. In some aspects, a method includes providing a microfluidic device having an upper chamber, a lower chamber, and a porous membrane separating the upper chamber from the lower chamber. The method further includes seeding walls of the lower chamber and a bottom surface of the membrane with endothelial cells. The method further includes providing a matrix within the upper chamber. The matrix includes fibrin gel and bone marrow cells. The method further includes filling or perfusing the upper chamber with a media.

Abstract: The invention provides solid, self-emulsifying compositions for oral administration. The compositions can comprise a population of particles comprising a cannabinoid or a terpene, a surfactant, and a solid carrier. The invention also encompasses methods for the preparation and use thereof.

Abstract: A computer-implemented transaction routing system including: a rule engine operative for receiving a flow of transaction data entities, using a processor for applying pre-imposed routing rules and determining routing of each data entity for which at least one pre-imposed routing rule is true to an external payment processor selected using the pre-imposed routing rule; and a transaction processing analyzer operative to accumulate data characterizing current handling by respective payment processors of at least transaction data entities routed to the respective payment processors by this system to maintain, by using a processor to compute, from the data, current statistics quantifying at least one handling aspect quality characterizing each of the plurality of supported payment processors, and to route at least each transaction data entity for which no pre-imposed routing-rules are true to a “best” payment processor selected by applying predetermined aspect combining criteria which prioritize the aspects to the

Abstract: Disclosed herein are ultrasonic probes and systems incorporating the probes. The probes are configured to produce an ultrasonic therapy exposure that, when applied to a kidney stone, will exert an acoustic radiation force sufficient to produce ultrasonic propulsion. Unlike previous probes configured to produce ultrasonic propulsion, however, the disclosed probes are engineered to produce a relatively large (both wide and long) therapy region effective to produce ultrasonic propulsion. This large therapy region allows the probe to move a plurality of kidney stones (or fragments from lithotripsy) in parallel, thereby providing the user the ability to clear several stones from an area simultaneously. This “broadly focused” probe is, in certain embodiments, combined in a single handheld unit with a typical ultrasound imaging probe to produce real-time imaging. Methods of using the probes and systems to move kidney stones are also provided.

Abstract: The invention is directed to a nanoprecipitate comprising a cannabinoid or a terpene, or combination thereof, a process of preparing the nanoprecipitate, and oral formulations comprising the nanoprecipitate, including beverage additives and edibles.

Abstract: The present disclosure relates to a microfluidic devices and methods for culturing bone marrow cells. Aspects include methods of preparing microfluidic devices and culturing bone marrow cells with the microfluidic devices. In some aspects, a method includes providing a microfluidic device having an upper chamber, a lower chamber, and a porous membrane separating the upper chamber from the lower chamber. The method further includes seeding walls of the lower chamber and a bottom surface of the membrane with endothelial cells. The method further includes providing a matrix within the upper chamber. The matrix includes fibrin gel and bone marrow cells. The method further includes filling or perfusing the upper chamber with a media.

Abstract: Targeting methods and devices for non-invasive therapy delivery are disclosed. In one embodiment, a method for targeting an object in a body using ultrasound includes: producing a therapy ultrasound waveform configured to fragment or comminute the object in the body using a therapy transducer of an ultrasound probe; and acquiring a sound waveform by a receiver. The sound waveform is at least in part caused by interactions of the therapy ultrasound with the object. The method also includes generating an indication of a targeting accuracy based on the acquired sound waveform.

Abstract: Devices, systems, and methods for controlling an intravascular imaging device are provided. For example, in one embodiment a method includes communicating a control signal to an actuator of the intravascular imaging device to cause oscillation of an imaging element of the intravascular imaging device, wherein the intravascular imaging device further includes an acoustic marker; receiving imaging data from the imaging element of the intravascular imaging device; identifying the acoustic marker in the imaging data by determining a correlation between the imaging data and a template representative of the acoustic marker; adjusting an aspect of the control signal based on identifying the acoustic marker; and communicating the adjusted control signal to the actuator of the intravascular imaging device.

Abstract: Devices, systems, and methods for controlling an intravascular imaging device are provided. For example, in one embodiment a method includes communicating a control signal to an actuator of the intravascular imaging device to cause oscillation of an imaging element of the intravascular imaging device, wherein the intravascular imaging device further includes an acoustic marker; receiving imaging data from the imaging element of the intravascular imaging device; identifying the acoustic marker in the imaging data by determining a correlation between the imaging data and a template representative of the acoustic marker; adjusting an aspect of the control signal based on identifying the acoustic marker; and communicating the adjusted control signal to the actuator of the intravascular imaging device.

Abstract: A computer-implemented transaction routing system including: a rule engine operative for receiving a flow of transaction data entities, using a processor for applying pre-imposed routing rules and determining routing of each data entity for which at least one pre-imposed routing rule is true to an external payment processor selected using the pre-imposed routing rule; and a transaction processing analyzer operative to accumulate data characterizing current handling by respective payment processors of at least transaction data entities routed to the respective payment processors by this system to maintain, by using a processor to compute, from the data, current statistics quantifying at least one handling aspect quality characterizing each of the plurality of supported payment processors, and to route at least each transaction data entity for which no pre-imposed routing-rules are true to a “best” payment processor selected by applying predetermined aspect combining criteria which prioritize the aspects to the

Abstract: Devices, systems, and methods for controlling an intravascular imaging device are provided. For example, in one embodiment a method includes communicating a control signal to an actuator of the intravascular imaging device to cause oscillation of an imaging element of the intravascular imaging device, wherein the intravascular imaging device further includes an acoustic marker; receiving imaging data from the imaging element of the intravascular imaging device; identifying the acoustic marker in the imaging data by determining a correlation between the imaging data and a template representative of the acoustic marker; adjusting an aspect of the control signal based on identifying the acoustic marker; and communicating the adjusted control signal to the actuator of the intravascular imaging device.

Abstract: Disclosed herein are ultrasonic probes and systems incorporating the probes. The probes are configured to produce an ultrasonic therapy exposure that, when applied to a kidney stone, will exert an acoustic radiation force sufficient to produce ultrasonic propulsion. Unlike previous probes configured to produce ultrasonic propulsion, however, the disclosed probes are engineered to produce a relatively large (both wide and long) therapy region effective to produce ultrasonic propulsion. This large therapy region allows the probe to move a plurality of kidney stones (or fragments from lithotripsy) in parallel, thereby providing the user the ability to clear several stones from an area simultaneously. This “broadly focused” probe is, in certain embodiments, combined in a single handheld unit with a typical ultrasound imaging probe to produce real-time imaging. Methods of using the probes and systems to move kidney stones are also provided.

Abstract: The disclosure relates to methods and compositions for improving homing of cells including mesenchymal stem cells (MSCs). Compositions include compounds described herein as capable of inducing expression by MSCs of cell surface homing ligand molecules such as CD1 la, promoting increased firm adhesion by MSCs in an in vitro shear flow assay, increasing binding to an adhesion molecule such as E-selectin or ICAM-1, and/or demonstrating anti-inflammatory activity upon in vivo systemic administration in cell therapy using human MSCs. Also described are screening methods to identify small molecule compounds for improving a homing function of MSCs.