Patents by Inventor Oren Menahem BECKER

Oren Menahem BECKER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperazine derivatives, pharmaceutical compositions and methods of use thereof
    Patent number: 12162868
    Abstract: The present invention relates to novel piperazine derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially for targeted therapy treatment of hyperproliferative disorders, including benign hyperproliferative disorders, cancer and pre-cancer conditions.
    Type: Grant
    Filed: August 8, 2021
    Date of Patent: December 10, 2024
    Assignee: Vidac Pharma Ltd..
    Inventors: Paul Salama, Vered Behar, Oren Menahem Becker
  • Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
    Patent number: 12083111
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: September 10, 2024
    Assignee: Vidac Pharma Ltd ..
    Inventors: Vered Behar, Oren Menahem Becker, Reut Yosef Hamo, Eyal Dor-On
  • Methods for preparation of jasmonate compounds
    Patent number: 11905250
    Abstract: This invention relates to methods for preparation of jasmonate compounds via a salt of jasmonic acid.
    Type: Grant
    Filed: January 6, 2019
    Date of Patent: February 20, 2024
    Assignee: VIDAC PHARMA LTD.
    Inventors: Paul Salama, Oren Menahem Becker
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR TREATING HEXOKINASE-2 (HK2)-EXPRESSING CANCERS
    Publication number: 20220143004
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for treating, inhibiting, or suppressing a hexokinase-2 (HK2)-expressing cancer.
    Type: Application
    Filed: January 25, 2022
    Publication date: May 12, 2022
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Hadas Tamar PAHIMA, Reut YOSEF HAMO
  • PIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20220098179
    Abstract: The present invention relates to novel piperazine derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially for targeted therapy treatment of hyperproliferative disorders, including benign hyperproliferative disorders, cancer and pre-cancer conditions.
    Type: Application
    Filed: August 8, 2021
    Publication date: March 31, 2022
    Applicant: Vidac Pharma Ltd.
    Inventors: Paul Salama, Vered Behar, Oren Menahem Becker
  • Use of hexokinase 2/mitochondria-detaching compounds for treating hexokinase-2 (HK2)-expressing cancers
    Patent number: 11266639
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for treating, inhibiting, or suppressing a hexokinase-2 (HK2)-expressing cancer.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: March 8, 2022
    Assignee: VIDAC PHARMA LTD.
    Inventors: Vered Behar, Oren Menahem Becker, Hadas Tamar Pahima, Reut Yosef Hamo
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR ACTIVATING IMMUNE RESPONSES
    Publication number: 20210369697
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Application
    Filed: August 17, 2021
    Publication date: December 2, 2021
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Reut YOSEF HAMO, Eyal DOR-ON
  • Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
    Patent number: 11096935
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: August 24, 2021
    Assignee: VIDAC PHARMA LTD
    Inventors: Vered Behar, Oren Menahem Becker, Reut Yosef Hamo, Eyal Dor-On
  • Piperazine derivatives, pharmaceutical compositions and methods of use thereof
    Patent number: 11084807
    Abstract: The present invention relates to novel piperazine derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially for targeted therapy treatment of hyperproliferative disorders, including benign hyperproliferative disorders, cancer and pre-cancer conditions.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: August 10, 2021
    Assignee: VIDAC PHARAMA LTD.
    Inventors: Paul Salama, Vered Behar, Oren Menahem Becker
  • METHODS FOR PREPARATION OF JASMONATE COMPOUNDS
    Publication number: 20210078949
    Abstract: This invention relates to methods for preparation of jasmonate compounds via a salt of jasmonic acid.
    Type: Application
    Filed: January 6, 2019
    Publication date: March 18, 2021
    Applicant: Vidac Pharma Ltd.
    Inventors: Paul SALAMA, Oren Menahem Becker
  • STABLE PHARMACEUTICAL COMPOSITIONS FOR TOPICAL ADMINISTRATION AND USES THEREOF
    Publication number: 20200297620
    Abstract: The present invention relates to novel pharmaceutical compositions for topical administration of a compound Formula I and methods of treating or preventing cancer or pre-cancerous conditions or benign hyperproliferative disorders, by administering the composition to a subject in need thereof. In particular, the present invention provides a stable formulation of active a compound of Formula I useful for the treatment of disorders such as actinic keratosis.
    Type: Application
    Filed: March 28, 2017
    Publication date: September 24, 2020
    Applicant: Vidac Pharma Ltd
    Inventors: Paul SALAMA, Oren Menahem BECKER, Chaim MANN BRICKMAN
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR ACTIVATING IMMUNE RESPONSES
    Publication number: 20200188381
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Application
    Filed: January 29, 2020
    Publication date: June 18, 2020
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Reut YOSEF HAMO, Eyal DOR-ON
  • Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
    Patent number: 10682346
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: June 16, 2020
    Assignee: VIDAC PHARMA LTD.
    Inventors: Vered Behar, Oren Menahem Becker, Reut Yosef Hamo, Eyal Dor-On
  • PIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20200031815
    Abstract: The present invention relates to novel piperazine derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially for targeted therapy treatment of hyperproliferative disorders, including benign hyperproliferative disorders, cancer and pre-cancer conditions.
    Type: Application
    Filed: August 17, 2017
    Publication date: January 30, 2020
    Inventors: Paul SALAMA, Oren Menahem BECKER, Vered BEHAR
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR TREATING HEXOKINASE-2 (HK2)-EXPRESSING CANCERS
    Publication number: 20180303820
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for treating, inhibiting, or suppressing a hexokinase-2 (HK2)-expressing cancer.
    Type: Application
    Filed: November 7, 2017
    Publication date: October 25, 2018
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Hadas Tamar PAHIMA, Reut YOSEF HAMO
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR ACTIVATING IMMUNE RESPONSES
    Publication number: 20180303819
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Application
    Filed: November 7, 2017
    Publication date: October 25, 2018
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Reut YOSEF HAMO, Eyal DOR-ON