Patents by Inventor Oren Rosen

Oren Rosen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180320139
    Abstract: Ex vivo and in vivo methods of expansion of renewable stem cells, expanded populations of renewable stem cells and their uses.
    Type: Application
    Filed: July 16, 2018
    Publication date: November 8, 2018
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Publication number: 20160097037
    Abstract: Ex vivo and in vivo methods of expansion of renewable stem cells, expanded populations of renewable stem cells and their uses.
    Type: Application
    Filed: December 15, 2015
    Publication date: April 7, 2016
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Patent number: 7955852
    Abstract: Ex vivo and in vivo methods of expansion of renewable stem cells, expanded populations of renewable stem cells and their uses.
    Type: Grant
    Filed: February 9, 2004
    Date of Patent: June 7, 2011
    Assignee: Gamida Cell Ltd.
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Publication number: 20110033427
    Abstract: Ex vivo and in vivo methods of expansion of renewable stem cells, expanded populations of renewable stem cells and their uses.
    Type: Application
    Filed: October 20, 2010
    Publication date: February 10, 2011
    Applicant: Gamida Cell LTD.
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Patent number: 7655225
    Abstract: Ex vivo and in vivo methods of expanding a population of stem and/or progenitor cells, while at the same time reversibly inhibiting differentiation of the stem and/or progenitor cells by providing the stem and/or progenitor cells with an effective amount of at least one copper chelate, so as to maintain a free copper concentration available to said cells substantially unchanged, to thereby expand the population of said stem and/or progenitor cells, while at the same time reversibly inhibit differentiation of said stem and/or progenitor cells.
    Type: Grant
    Filed: February 19, 2008
    Date of Patent: February 2, 2010
    Assignee: Gamida Cell, Ltd.
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Publication number: 20080279828
    Abstract: Ex vivo and in vivo methods of expanding a population of stem and/or progenitor cells, while at the same time reversibly inhibiting differentiation of the stem and/or progenitor cells by providing the stem and/or progenitor cells with an effective amount of at least one copper chelate, so as to maintain a free copper concentration available to said cells substantially unchanged, to thereby expand the population of said stem and/or progenitor cells, while at the same time reversibly inhibit differentiation of said stem and/or progenitor cells.
    Type: Application
    Filed: February 19, 2008
    Publication date: November 13, 2008
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Patent number: 7344881
    Abstract: Ex vivo and in vivo methods of expanding a population of stem and/or progenitor cells, while at the same time reversibly inhibiting differentiation of the stem and/or progenitor cells by providing the stem and/or progenitor cells with an effective amount of at least one copper chelate, so as to maintain a free copper concentration available to said cells substantially unchanged, to thereby expand the population of said stem and/or progenitor cells, while at the same time reversibly inhibit differentiation of said stem and/or progenitor cells.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: March 18, 2008
    Assignee: Gamida Cell Ltd.
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Publication number: 20050054097
    Abstract: Ex-vivo methods of expanding hematopoietic stem cells of hematopoietic mononuclear cells that comprise a major fraction of hematopoietic committed cells and a minor fraction of hematopoietic stem and progenitor cells, expanded populations of hematopoietic stem cells obtained thereby and their uses are disclosed.
    Type: Application
    Filed: January 29, 2004
    Publication date: March 10, 2005
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Publication number: 20050008624
    Abstract: Ex vivo and in vivo methods of expansion of renewable stem cells, expanded populations of renewable stem cells and their uses.
    Type: Application
    Filed: February 9, 2004
    Publication date: January 13, 2005
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Patent number: 6841710
    Abstract: The present invention describes novel, cost-effective and rapid processes suitable for recycling and degradation of specially designed plastics, which are instantly degradable synthetic polymeric plastics having the characteristics and properties of conventional forms of plastics. These novel plastic products are made from a variety of compositions of polymers and their compatible nontoxic modifiers. The resulting novel instant degradable plastic products retain latent solubility properties which are triggered upon mild chemical processes of the present invention, thus enabling cost effective and facile recycling of plastic refuge.
    Type: Grant
    Filed: August 21, 2003
    Date of Patent: January 11, 2005
    Inventor: Oren Rosen
  • Publication number: 20040076603
    Abstract: Ex vivo and in vivo methods of expanding a population of stem and/or progenitor cells, while at the same time reversibly inhibiting differentiation of the stem and/or progenitor cells by providing the stem and/or progenitor cells with an effective amount of at least one copper chelate, so as to maintain a free copper concentration available to said cells substantially unchanged, to thereby expand the population of said stem and/or progenitor cells, while at the same time reversibly inhibit differentiation of said stem and/or progenitor cells.
    Type: Application
    Filed: April 18, 2003
    Publication date: April 22, 2004
    Inventors: Tony Peled, Avi Treves, Oren Rosen
  • Publication number: 20040064005
    Abstract: The present invention describes novel, cost-effective and rapid processes suitable for recycling and degradation of specially designed plastics, which are instantly degradable synthetic polymeric plastics having the characteristics and properties of conventional forms of plastics. These novel plastic products are made from a variety of compositions of polymers and their compatible nontoxic modifiers. The resulting novel instant degradable plastic products retain latent solubility properties which are triggered upon mild chemical processes of the present invention, thus enabling cost effective and facile recycling of plastic refuge.
    Type: Application
    Filed: August 21, 2003
    Publication date: April 1, 2004
    Inventor: Oren Rosen
  • Publication number: 20030232952
    Abstract: A novel class of instant degradable synthetic polymeric plastics having the characteristics and properties of conventional forms of plastics is developed by providing a new application advantage of incorporating latent, labile, dormant chemical bond nuclei such as disulfide and sulfenyl derivatives of the plastic compounds with latent nucleophilic properties. The special advantage of the instant degradable polymers over the existing biodegradable and other degradable polymer counterparts, is their engineering and design, which makes the kinetics of their degradation instant, and the chemical and physical properties of their by-products allows soluble dissolution into non-toxic aqueous solvent media, thus enabling a practical treatment of waste and avoiding bio-hazardous pollution of the environment. These novel plastic products are made from a variety of compositions of polymers and their compatible nontoxic modifiers.
    Type: Application
    Filed: June 19, 2003
    Publication date: December 18, 2003
    Inventor: Oren Rosen
  • Publication number: 20020183418
    Abstract: A novel class of instantly degradable synthetic polymeric plastics having the characteristics and properties of conventional forms of plastics is developed by providing the disulfide and sulfenyl derivatives of the plastic compounds with latent nucleophilic properties. These novel plastic products are made from a variety of compositions of polymers and their compatible nontoxic modifiers. The resulting novel instant degradable plastic products retain latent solubility properties that are triggered upon mild chemical reaction, thus enabling cost effective and facile recycling of plastic refuge.
    Type: Application
    Filed: February 2, 2001
    Publication date: December 5, 2002
    Inventor: Oren Rosen
  • Publication number: 20020156333
    Abstract: The present invention describes novel, cost-effective and rapid processes suitable for degradation and recycling of specially designed plastics, which are defined as instantly degradable synthetic polymeric plastics having the characteristics and properties of conventional forms of plastics. These novel plastic products are made from a variety of compositions of polymers and their compatible nontoxic modifiers. The resulting novel instant degradable plastic products retain latent solubility properties which are triggered upon mild chemical processes of the present invention, thus enabling cost effective and facile recycling of plastic refuge.
    Type: Application
    Filed: February 2, 2001
    Publication date: October 24, 2002
    Inventor: Oren Rosen