Patents by Inventor Orest William Blaschuk

Orest William Blaschuk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of cell adhesion, methods and compositions therefor
    Patent number: 10647672
    Abstract: Compounds with activity as modulators of cell adhesion are disclosed. The compounds are derivatives of piperidin-4-amine. In some embodiments, a compound can be linked to a targeting agent, a pharmaceutically active substance and/or a support material. Methods for enhancing or inhibiting classical cadherin-mediated functions are also disclosed. The compounds can be used for the treatment or prevention of a variety of diseases including cancer. Compositions and devices, including skin patches comprising a compound are also disclosed. In addition, methods of synthesis of the compounds are provided.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: May 12, 2020
    Assignee: Zonula, Inc.
    Inventor: Orest William Blaschuk
  • Modulators of cell adhesion, methods and compositions therefor
    Publication number: 20200048200
    Abstract: Compounds with activity as modulators of cell adhesion are disclosed. The compounds are derivatives of piperidin-4-amine. In some embodiments, a compound can be linked to a targeting agent, a pharmaceutically active substance and/or a support material. Methods for enhancing or inhibiting classical cadherin-mediated functions are also disclosed. The compounds can be used for the treatment or prevention of a variety of diseases including cancer. Compositions and devices, including skin patches comprising a compound are also disclosed. In addition, methods of synthesis of the compounds are provided.
    Type: Application
    Filed: October 29, 2019
    Publication date: February 13, 2020
    Inventor: Orest William Blaschuk
  • Modulators of cell adhesion, methods and compositions therefor
    Patent number: 10494345
    Abstract: Compounds with activity as modulators of cell adhesion are disclosed. The compounds are derivatives of piperidin-4-amine. In some embodiments, a compound can be linked to a targeting agent, a pharmaceutically active substance and/or a support material. Methods for enhancing or inhibiting classical cadherin-mediated functions are also disclosed. The compounds can be used for the treatment or prevention of a variety of diseases including cancer. Compositions and devices, including skin patches comprising a compound are also disclosed. In addition, methods of synthesis of the compounds are provided.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: December 3, 2019
    Assignee: Zonula, Inc.
    Inventors: Arkadii Vaisburg, Orest William Blaschuk
  • Modulators of cell adhesion, methods and compositions therefor
    Publication number: 20190100493
    Abstract: Compounds with activity as modulators of cell adhesion are disclosed. The compounds are derivatives of piperidin-4-amine. In some embodiments, a compound can be linked to a targeting agent, a pharmaceutically active substance and/or a support material. Methods for enhancing or inhibiting classical cadherin-mediated functions are also disclosed. The compounds can be used for the treatment or prevention of a variety of diseases including cancer. Compositions and devices, including skin patches comprising a compound are also disclosed. In addition, methods of synthesis of the compounds are provided.
    Type: Application
    Filed: October 1, 2018
    Publication date: April 4, 2019
    Inventors: Arkadii Vaisburg, Orest William Blaschuk