Patents by Inventor Orhan Unal

Orhan Unal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8532742
    Abstract: A system and method of both tracking a medical device and generating an image in real time from the same set of radial data. A multi-mode medical device system having tracking, imaging, and visualizing capabilities is coupled to an MR scanner and multiple-echo VIPR acquisition sequence is applied to simultaneously provide conventional real-time imaging of the target region using an external coil, 3D tip-tracking information, and a localized higher-quality image showing the region surrounding the medical device using an internal multi-mode coil.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: September 10, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Orhan Unal, Ethan K. Brodsky, Krishna N. Kurpad
  • Patent number: 8457712
    Abstract: A multi-mode medical device system and method of performing an interventional procedure. The multi-mode medical device system can be capable of MR internal imaging and of being tracked using an MRI system. The multi-mode medical device system can include a medical device, and an electrical circuit coupled to the medical device and electrically coupled to the MRI system. The electrical circuit can include a tracking device configured to transmit a signal to the MRI system indicative of the position of the tracking device relative to a roadmap image, and an imaging device electrically coupled to the tracking device and configured to internally image anatomical structures from the point of view of the medical device. The imaging device can be further configured to be visualized using MR imaging. Tracking the tracking device and internally imaging with the imaging device can be performed in a single pass of the multi-mode medical device system.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: June 4, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Orhan Unal, Krishna N. Kurpad
  • Patent number: 8412306
    Abstract: A system and method of tracking a medical device and generating an image of a target area. The medical device includes a tracking device to create an imaging field-of-view that extends beyond the tip of the medical device while allowing the tip of the medical device to be visualized. The medical device further includes an imaging/visualization device to create an imaging field from the point of view of the medical device. A voltage standing wave suppression device is formed on the exterior surface of the medical device to prevent the formation of voltage standing waves and localized tissue heating. The voltage standing wave suppression device includes two cable traps spaced apart from one another with each cable trap being formed of a closely packed coiled region of a conductor extending the length of the medical device.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: April 2, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Krishna N. Kurpad, Orhan Unal
  • Patent number: 8112145
    Abstract: An assessment of myocardial viability in a subject is performed by acquiring an MR image which distinguishes infarcted myocardium from normal myocardium. A contrast agent is used and after a waiting period, a cardiac-gated segmented inversion recovery gradient-recalled radial sampling technique is employed to acquire NMR data over a substantial portion of the cardiac cycle. By interleaving the radial sampling patterns, images can be reconstructed over a range of possible TI intervals enabling the optimal TI for maximum contrast to be retrospectively selected.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: February 7, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Thomas M. Grist, Orhan Unal
  • Publication number: 20080208031
    Abstract: A system and method of tracking a medical device and generating an image of a target area. The medical device includes a tracking device to create an imaging field-of-view that extends beyond the tip of the medical device while allowing the tip of the medical device to be visualized. The medical device further includes an imaging/visualization device to create an imaging field from the point of view of the medical device. A voltage standing wave suppression device is formed on the exterior surface of the medical device to prevent the formation of voltage standing waves and localized tissue heating. The voltage standing wave suppression device includes two cable traps spaced apart from one another with each cable trap being formed of a closely packed coiled region of a conductor extending the length of the medical device.
    Type: Application
    Filed: March 27, 2007
    Publication date: August 28, 2008
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Krishna N. Kurpad, Orhan Unal
  • Publication number: 20080208039
    Abstract: A system and method of tracking a medical device and generating an image of a target area. The medical device includes a Helmholtz coil pair to create an imaging field-of-view that extends beyond the tip of the medical device while allowing the tip of the medical device to be visualized. The Helmholtz coil pair provides the ability to generate images forward of the medical device tip to ensure that the tip of the medical device will not puncture the target tissue or vasculature.
    Type: Application
    Filed: March 27, 2007
    Publication date: August 28, 2008
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Krishna N. Kurpad, Orhan Unal
  • Publication number: 20080183070
    Abstract: A multi-mode medical device system and method of using same to perform an interventional procedure. The multi-mode medical device system includes a medical device and an electrical circuit coupled to the medical device. The electrical circuit includes an integrated tracking device (e.g., a solenoid) and an imaging/visualizing device (e.g., a resonant loop). The multi-mode medical device system also includes a thermal ablation device coupled to the medical device and to the tracking device.
    Type: Application
    Filed: January 29, 2007
    Publication date: July 31, 2008
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Orhan Unal, Krishna N. Kurpad, Christopher L. Brace
  • Publication number: 20080114235
    Abstract: A system and method of both tracking a medical device and generating an image in real time from the same set of radial data. A multi-mode medical device system having tracking, imaging, and visualizing capabilities is coupled to an MR scanner and multiple-echo VIPR acquisition sequence is applied to simultaneously provide conventional real-time imaging of the target region using an external coil, 3D tip-tracking information, and a localized higher-quality image showing the region surrounding the medical device using an internal multi-mode coil.
    Type: Application
    Filed: March 5, 2007
    Publication date: May 15, 2008
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Orhan Unal, Ethan K. Brodsky, Krishna N. Kurpad
  • Publication number: 20070167726
    Abstract: A multi-mode medical device system and method of performing an interventional procedure. The multi-mode medical device system can be capable of MR internal imaging and of being tracked using an MRI system. The multi-mode medical device system can include a medical device, and an electrical circuit coupled to the medical device and electrically coupled to the MRI system. The electrical circuit can include a tracking device configured to transmit a signal to the MRI system indicative of the position of the tracking device relative to a roadmap image, and an imaging device electrically coupled to the tracking device and configured to internally image anatomical structures from the point of view of the medical device. The imaging device can be further configured to be visualized using MR imaging. Tracking the tracking device and internally imaging with the imaging device can be performed in a single pass of the multi-mode medical device system.
    Type: Application
    Filed: December 30, 2005
    Publication date: July 19, 2007
    Inventors: Orhan Unal, Krishna Kurpad
  • Publication number: 20070156042
    Abstract: A medical device system capable of being tracked and visualized using a magnetic resonance (MR) device, and a method for tracking and visualizing a medical device system using MR imaging. The medical device system can include a medical device, a tracking device, and a visualizing device. The tracking device can provide feedback indicative of the position of the tracking device. The visualizing device can be coupled to at least a portion of the medical device such that the respective portion of the medical device is visualized using magnetic resonance. The method for tracking and visualizing a medical device system can include providing a medical device having a nonlinear configuration, tracking a tracking device, and visualizing a visualizing device to allow visualization of the nonlinear configuration of the medical device. Some embodiments include a medical device system capable of being visualized in the presence and absence of contrast agents.
    Type: Application
    Filed: December 30, 2005
    Publication date: July 5, 2007
    Inventor: Orhan Unal
  • Publication number: 20050272997
    Abstract: An assessment of myocardial viability in a subject is performed by acquiring an MR image which distinguishes infarcted myocardium from normal myocardium. A contrast agent is used and after a waiting period, a cardiac-gated segmented inversion recovery gradient-recalled radial sampling technique is employed to acquire NMR data over a substantial portion of the cardiac cycle. By interleaving the radial sampling patterns, images can be reconstructed over a range of possible TI intervals enabling the optimal TI for maximum contrast to be retrospectively selected.
    Type: Application
    Filed: June 3, 2004
    Publication date: December 8, 2005
    Inventors: Thomas Grist, Orhan Unal
  • Patent number: 6896873
    Abstract: The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex.
    Type: Grant
    Filed: March 12, 2002
    Date of Patent: May 24, 2005
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Richard Frayne, Charles M. Strother, Orhan Unal, Zhihao Yang, Abukar Wehelie, Hyuk Yu
  • Patent number: 6896874
    Abstract: The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex. The present invention also provides methods by which pre-existing polymers and medical devices may be made MR-imageable. The invention also provides methods of improving MR-imageability of polymers and medical devices by encapsulating the polymers and medical devices with hydrogels.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: May 24, 2005
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Junwei Li, Orhan Unal, Xiqun Jiang, Charles Milton Strother, Hyuk Yu
  • Publication number: 20040253292
    Abstract: A coating that emits magnetic resonance signals and a method for coating medical devices therewith are provided. The coating may include a paramagnetic-metal-ion/ligand encapsulated or sequestered by a hydrogel. Methods by which pre-existing medical devices may be made MR-imageable are also provided, along with MR-imageable medical devices, and methods of using the medical devices.
    Type: Application
    Filed: April 23, 2003
    Publication date: December 16, 2004
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Orhan Unal, Junwei Li, Charles Milton Strother, Hyuk Yu
  • Publication number: 20030099764
    Abstract: The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex. The present invention also provides methods by which pre-existing polymers and medical devices may be made MR-imageable. The invention also provides methods of improving MR-imageability of polymers and medical devices by encapsulating the polymers and medical devices with hydrogels.
    Type: Application
    Filed: May 9, 2002
    Publication date: May 29, 2003
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Junwei Li, Orhan Unal, Xiqun Jiang, Charles Milton Strother, Hyuk Yu
  • Publication number: 20020176822
    Abstract: The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex.
    Type: Application
    Filed: March 12, 2002
    Publication date: November 28, 2002
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Richard Frayne, Charles M. Strother, Orhan Unal, Zhihao Yang, Abukar Wehelie, Hyuk Yu
  • Patent number: 6361759
    Abstract: The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex.
    Type: Grant
    Filed: June 25, 1998
    Date of Patent: March 26, 2002
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Richard Frayne, Charles M. Strother, Orhan Unal, Zhihao Yang, Abukar Wehelie, Hyuk Yu