Patents by Inventor Orlando Zepeda

Orlando Zepeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of HIV-1 infection and AIDS
    Patent number: 9956260
    Abstract: Provided herein are compositions and methods for the treatment of a patient having an HIV-1 infection and/or AIDS. More specifically this invention provides treatment of an HIV-1 infection and/or AIDS using small molecule compounds, such as inhibitors for the activation and/or activity of caspase-1. Inhibitors for the activation and/or activity of caspase-1 also prevent the cell death of CD4 T-cells in a population of CD4 T-cells comprising HIV-1 infected CD4 T-cells and uninfected CD4 T-cells, In addition, caspase-1 inhibitors inhibit inflammation, and pyroptosis.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: May 1, 2018
    Assignee: The J. David Gladstone Institutes
    Inventors: Warner C. Greene, Gilad Doitsh, Orlando Zepeda, Nicole Galloway
  • Treatment of HIV-1 infection and AIDS
    Patent number: 9352010
    Abstract: Provided herein are compositions and methods for the treatment of a patient having an HIV-1 infection and/or AIDS. More specifically this invention provides treatment of an HIV-1 infection and/or AIDS using small molecule compounds, such as inhibitors for the activation and/or activity of caspase-1. Inhibitors for the activation and/or activity of caspase-1 also prevent the cell death of CD4 T-cells in a population of CD4 T-cells comprising HIV-1 infected CD4 T-cells and uninfected CD4 T-cells. In addition, caspase-1 inhibitors inhibit inflammation, and pyroptosis.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: May 31, 2016
    Assignee: The J. David Gladstone Institutes
    Inventors: Warner C. Greene, Gilad Doitsh, Orlando Zepeda, Nicole Galloway
  • Treatment Of HIV-1 Infection And AIDS
    Publication number: 20160008420
    Abstract: Provided herein are compositions and methods for the treatment of a patient having an HIV-1 infection and/or AIDS. More specifically this invention provides treatment of an HIV-1 infection and/or AIDS using small molecule compounds, such as inhibitors for the activation and/or activity of caspase-1. Inhibitors for the activation and/or activity of caspase-1 also prevent the cell death of CD4 T-cells in a population of CD4 T-cells comprising HIV-1 infected CD4 T-cells and uninfected CD4 T-cells. In addition, caspase-1 inhibitors inhibit inflammation, and pyroptosis.
    Type: Application
    Filed: September 4, 2015
    Publication date: January 14, 2016
    Inventors: Warner C. GREENE, Gilad Doitsh, Orlando Zepeda, Nicole Galloway
  • Treatment Of HIV-1 Infection And AIDS
    Publication number: 20150343011
    Abstract: Provided herein are compositions and methods for the treatment of a patient having an HIV-1 infection and/or AIDS. More specifically this invention provides treatment of an HIV-1 infection and/or AIDS using small molecule compounds, such as inhibitors for the activation and/or activity of caspase-1. Inhibitors for the activation and/or activity of caspase-1 also prevent the cell death of CD4 T-cells in a population of CD4 T-cells comprising HIV-1 infected CD4 T-cells and uninfected CD4 T-cells. In addition, caspase-1 inhibitors inhibit inflammation, and pyroptosis.
    Type: Application
    Filed: June 4, 2015
    Publication date: December 3, 2015
    Inventors: Warner C. GREENE, Gilad Doitsh, Orlando Zepeda, Nicole Galloway