Patents by Inventor Orly Devary

Orly Devary has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Shortened secreted polypeptides
    Patent number: 9296786
    Abstract: The present invention relates to an isolated polypeptide comprising (a) the amino acid sequence set forth in SEQ ID NO: 21; or (b) an amino acid sequence that is at least 95% identical to SEQ ID NO: 21, and to therapeutic treatments based thereon.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: March 29, 2016
    Assignee: Two To Biotech Ltd.
    Inventors: Tamara Sandler, Orly Devary
  • NOVEL POLYPEPTIDES
    Publication number: 20160083445
    Abstract: The present invention relates to an isolated polypeptide comprising (a) the amino acid sequence set forth in SEQ ID NO: 2; or (b) an amino acid sequence that is at least 95% identical to SEQ ID NO: 2, and to therapeutic treatments based thereon.
    Type: Application
    Filed: November 30, 2015
    Publication date: March 24, 2016
    Inventors: Tamara SANDLER, Orly DEVARY
  • Anti-KTPAF50 antibodies and their uses in therapeutic and diagnostic methods
    Patent number: 9150642
    Abstract: Polyclonal and monoclonal antibodies which specifically recognize the KTPAF50 protein, and compositions comprising thereof are provided. Also provided are uses of the KTPAF50-specific antibodies, in the diagnosis and therapeutic of conditions such as cancer, autoimmune diseases, graft rejection, neurodegenerative diseases and diabetes.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: October 6, 2015
    Assignee: Two To Biotech Ltd.
    Inventors: Orly Devary, Tamara Sandler
  • NOVEL PEPTIDES AND USES THEREOF IN THERAPEUTIC METHODS
    Publication number: 20140155324
    Abstract: The invention relates to polypeptides exhibiting metabolic-modulating as well as immunomodulatory properties, nucleic acids encoding them, compositions comprising them, and methods of treating metabolic disorders and/or immune-related disorders comprising their administration and to their use in preparing pharmaceutical compositions for the treatment, amelioration, prophylaxis or delaying the onset of at least one of a metabolic disorder and an immune-related disorder.
    Type: Application
    Filed: August 6, 2012
    Publication date: June 5, 2014
    Applicant: TWO TO BIOTECH LTD.
    Inventors: Tamara Sandler, Orly Devary
  • NOVEL POLYPEPTIDES
    Publication number: 20140121153
    Abstract: The present invention relates to an isolated polypeptide comprising (a) the amino acid sequence set forth in SEQ ID NO: 21; or (b) an amino acid sequence that is at least 95% identical to SEQ ID NO: 21, and to therapeutic treatments based thereon.
    Type: Application
    Filed: January 2, 2014
    Publication date: May 1, 2014
    Inventors: Tamara SANDLER, Orly DEVARY
  • Proteins
    Patent number: 8647632
    Abstract: Provided herein are four polypeptides, named PRT5, PRT6, PRT7 and PRT8, the nucleic acids encoding the same, compositions comprising the proteins, as well as their uses in therapeutic and diagnostic methods. Antibodies which specifically recognize the polypeptides are also provided, as well as their uses. Characterization of each protein showed that PRT5 and PRT8 are involved in glucose metabolism, PRT6 is involved in androgen regulation, while PRT7 correlates with cancer.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: February 11, 2014
    Assignee: Two to Biotech Ltd.
    Inventors: Tamara Sandler, Orly Devary
  • Protein KTPAF50
    Patent number: 8329861
    Abstract: Provided is a novel, isolated polypeptide including an amino acid sequence of SEQ. ID. NO: 2 or SEQ. ID. NO: 4, and the nucleic acid molecule which encodes it. The polypeptide may be used in a method for treating various diseases including cancer, immune associated, viral and inflammatory diseases.
    Type: Grant
    Filed: December 25, 2008
    Date of Patent: December 11, 2012
    Assignee: Two To Biotech Ltd.
    Inventors: Tamar Sandler, Orly Devary
  • NOVEL PROTEINS
    Publication number: 20120121602
    Abstract: Provided herein are four polypeptides, named PRT5, PRT6, PRT7 and PRT8, the nucleic acids encoding the same, compositions comprising the proteins, as well as their uses in therapeutic and diagnostic methods. Antibodies which specifically recognize the polypeptides are also provided, as well as their uses. Characterization of each protein showed that PRT5 and PRT8 are involved in glucose metabolism, PRT6 is involved in androgen regulation, while PRT7 correlates with cancer.
    Type: Application
    Filed: August 2, 2010
    Publication date: May 17, 2012
    Applicant: TWO TO BIOTECH LTD.
    Inventors: Tamara Sandler, Orly Devary
  • NOVEL ANTIBODIES AND THEIR USES IN THERAPEUTIC AND DIAGNOSTIC METHODS
    Publication number: 20120100147
    Abstract: Polyclonal and monoclonal antibodies which specifically recognize the KTPAF50 protein, and compositions comprising thereof are provided. Also provided are uses of the KTPAF50-specific antibodies, in the diagnosis and therapeutic of conditions such as cancer, autoimmune diseases, graft rejection, neurodegenerative diseases and diabetes.
    Type: Application
    Filed: June 29, 2010
    Publication date: April 26, 2012
    Applicant: TWO TO BIOTECH LTD.
    Inventors: Orly Devary, Tamara Sandler
  • NOVEL PROTEIN
    Publication number: 20100286026
    Abstract: Provided is a novel, isolated polypeptide including an amino acid sequence of SEQ. ID. NO: 2 or SEQ. ID. NO: 4, and the nucleic acid molecule which encodes it. The polypeptide may be used in a method for treating various diseases including cancer, immune associated, viral and inflammatory diseases.
    Type: Application
    Filed: December 25, 2008
    Publication date: November 11, 2010
    Applicant: TWO TO BIOTECH LTD.
    Inventors: Tamar Sandler, Orly Devary