Patents by Inventor Orna Kurlat

Orna Kurlat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of purified donepezil maleate for preparing pharmaceutically pure amorphous donepezil hydrochloride
    Patent number: 7592459
    Abstract: The present invention provides a crystalline donepezil maleate, which is used as an intermediate in the preparation of donepezil hydrochloride. Also provided are novel processes for producing same in substantially pure form and a process for producing pharmaceutically pure amorphous donepezil hydrochloride therefrom.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: September 22, 2009
    Assignee: Chemagis Ltd.
    Inventors: Oded Arad, Lior Zelikovitch, Mohammed Alnabari, Michael Brand, Irina Gribun, Ada Salman, Meital Shiffer, Moty Shookrun, Orna Kurlat, Moshe Bentolila, Joseph Kaspi
  • Process for alkylating secondary amines and the use in donepezil preparation thereof
    Publication number: 20060122227
    Abstract: The present invention relates to an improved process of alkylating secondary amines, more particularly of alkylating compounds having amino piperidinic group, which are useful as donepezil intermediates, wherein an alcohol serves as reaction facilitator thus enabling to obtain donepezil and salts thereof in high quality and yield. The present invention also relates to the prevention of unwanted alkylation of donepezil precursors, having amino piperidinic group, by using suitable reaction conditions.
    Type: Application
    Filed: September 27, 2005
    Publication date: June 8, 2006
    Inventors: Lior Zelikovitch, Oded Arad, Mohammed Alnabari, Yana Sery, Orna Kurlat, Moshe Bentolila, Aric Abadayev, Hanit Marom, Hila Isenberg, Joseph Kaspi
  • Use of purified donepezil maleate for preparing pharmaceutically pure amorphous donepezil hydrochloride
    Publication number: 20060069125
    Abstract: The present invention provides a crystalline donepezil maleate, which is used as an intermediate in the preparation of donepezil hydrochloride. Also provided are novel processes for producing same in substantially pure form and a process for producing pharmaceutically pure amorphous donepezil hydrochloride therefrom.
    Type: Application
    Filed: September 27, 2005
    Publication date: March 30, 2006
    Inventors: Oded Arad, Lior Zelikovitch, Mohammed Alnabari, Michael Brand, Irina Gribun, Ada Salman, Meital Shiffer, Moty Shookrun, Orna Kurlat, Moshe Bentolila, Joseph Kaspi