Patents by Inventor Orna SINGER

Orna SINGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Large scale production of retinal pigment epithelial cells
    Patent number: 11746324
    Abstract: A method of generating retinal pigment epithelial (RPE) cells is disclosed. The method comprises: (a) culturing human pluripotent stem cells in a human feeder cell-conditioned medium to obtain a cultured population of human pluripotent stem cells; (b) culturing said cultured population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; and (c) culturing said differentiating cells in a medium comprising one or more members of the TGF? superfamily.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: September 5, 2023
    Assignee: Hadasit Medical Research Services and Development Ltd.
    Inventors: Benjamin Eithan Reubinoff, Orna Singer
  • LARGE SCALE PRODUCTION OF RETINAL PIGMENT EPITHELIAL CELLS
    Publication number: 20220098551
    Abstract: A method of generating retinal pigment epithelial (RPE) cells is disclosed. The method comprises: (a) culturing human pluripotent stem cells in a human feeder cell-conditioned medium to obtain a cultured population of human pluripotent stem cells; (b) culturing said cultured population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; and (c) culturing said differentiating cells in a medium comprising one or more members of the TGF? superfamily.
    Type: Application
    Filed: December 10, 2021
    Publication date: March 31, 2022
    Inventors: Benjamin Eithan REUBINOFF, Orna SINGER
  • Large scale production of retinal pigment epithelial cells
    Patent number: 11230696
    Abstract: A method of generating retinal pigment epithelial (RPE) cells is disclosed. The method comprises: (a) culturing human pluripotent stem cells in a human feeder cell-conditioned medium to obtain a cultured population of human pluripotent stem cells; (b) culturing said cultured population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; and (c) culturing said differentiating cells in a medium comprising one or more members of the TGF? superfamily.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: January 25, 2022
    Assignee: Hadasit Medical Research Services and Development Ltd.
    Inventors: Benjamin Eithan Reubinoff, Orna Singer
  • Preparation of Retinal Pigment Epithelium Cells
    Publication number: 20180312805
    Abstract: A method of generating retinal pigment epithelium cells is disclosed. Cell populations comprising same and uses thereof are also disclosed.
    Type: Application
    Filed: October 26, 2016
    Publication date: November 1, 2018
    Applicants: CELL CURE NEUROSCIENCES LTD., HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
    Inventors: Benjamin Eithan REUBINOFF, Orna SINGER, Osnat BOHANA-KASHTAN, Ofer WISER
  • LARGE SCALE PRODUCTION OF RETINAL PIGMENT EPITHELIAL CELLS
    Publication number: 20180216064
    Abstract: A method of generating retinal pigment epithelial (RPE) cells is disclosed. The method comprises: (a) culturing human pluripotent stem cells in a human feeder cell-conditioned medium to obtain a cultured population of human pluripotent stem cells; (b) culturing said cultured population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; and (c) culturing said differentiating cells in a medium comprising one or more members of the TGF? superfamily.
    Type: Application
    Filed: July 28, 2016
    Publication date: August 2, 2018
    Applicant: Hadasit Medical Research Services and Development Ltd.
    Inventors: Benjamin Eithan REUBINOFF, Orna SINGER