Patents by Inventor Orsolya Csuka

Orsolya Csuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6297216
    Abstract: The invention features novel peptide derivatives called Reversins, and provides for their use in a method of reducing the activity of the multi-drug transporter protein MDR1 in order to overcome multidrug resistance in a mammal. The peptide derivatives are of the formula (I) X1n-X2-X3(X4)n-X5, wherein n is 0 or 1, and each n is the same or different; X1 is BOC, BOC-Asu, Z-Asu, benzyloxycarbonyl, Glu(OBzl)-OBzl, Trp-OMe, Trp-Phe-OMe, Phe-Trp-OMe, Phe-Phe-OtBu, Trp-Trp-OtBu, indoloacetyl, benzoyl, an alkylanine of 1-4 carbons, dibenzylamide, tryptamide, 1-amino-adamantine, aminomethylcyclohexane, indoline, phenylethylamide or dicyclohexylamide; X2 is Glu(OBzl), Asp(OBzl), succinyl, O,O-dibenzoyltartaroyl, diphenoyl, muconyl, Thx, Cpa, Asu, Nal, Pen, Phg, Dbt, Lys(BOC), Lys(Z), Cys(Bzl), Thr(Bzl), Glu(OtBu), tert.-Leu, Leu, Nle, Pro, Phe, Tyr(Bzl), or Ser(Bal); X3 is Asp, Asu, Lys, Glu, Trp, Thx, Cpa, Nal, Pen, Phg, Dbt, Glu(OtBu), tert.
    Type: Grant
    Filed: February 19, 1997
    Date of Patent: October 2, 2001
    Assignee: Solvo Biotechnology
    Inventors: Balazs Sarkadi, Janos Seprodi, Orsolya Csuka, Maria Magocsi, Imre Mezo, Istvan Palyi, Istvan Teplan, Zsolt Vadasz, Borbala Vincze
  • Patent number: 5480870
    Abstract: The invention relates to tumor-inhibiting heptapeptide and octapeptide amide derivatives and to a method of treating mammals, including men, suffering from tumors or from the excessive secretion of insulin, glucagon or growth hormone using these compounds.
    Type: Grant
    Filed: April 26, 1994
    Date of Patent: January 2, 1996
    Assignee: Biosignal Kutato-Fejlesztokft
    Inventors: Gyorgy Keri, Imre Mezo, Aniko Horvath, Zsolt Vadasz, Istvan Teplan, Agnes Balogh, Orsolya Csuka, Gyongyi Bokonyi, Balas Szoke, Judit Horvath, Miklos Idei, Janos Seprodi