Patents by Inventor Orville G. Kolterman

Orville G. Kolterman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230372411
    Abstract: Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject.
    Type: Application
    Filed: January 23, 2023
    Publication date: November 23, 2023
    Inventors: Colleen CUTCLIFFE, John S. EID, Tomer ALTMAN, Orville G. KOLTERMAN, James H. BULLARD
  • Patent number: 11583558
    Abstract: Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: February 21, 2023
    Assignee: PENDULUM THERAPEUTICS, INC.
    Inventors: Colleen Cutcliffe, John S. Eid, Tomer Altman, Orville G. Kolterman, James H. Bullard
  • Publication number: 20200268811
    Abstract: Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject.
    Type: Application
    Filed: February 28, 2020
    Publication date: August 27, 2020
    Inventors: Colleen CUTCLIFFE, John S. EID, Tomer ALTMAN, Orville G. KOLTERMAN, James H. BULLARD
  • Publication number: 20200121738
    Abstract: The present disclosure provides a method for formulating a composition of isolated and purified microbes. The present disclosure provides methods for formulating a composition for administration to a subject in need thereof. The method can comprise obtaining a mixture that is substantially dry and comprises about 10% or less residual moisture. The mixture can comprise a population of isolated and purified microbes and a pharmaceutically acceptable carrier. The population can comprise one or more obligate anaerobes that are oxygen-stable. The methods can further comprise encapsulating said mixture in an enteric-coated capsule for delivery to said subject.
    Type: Application
    Filed: June 4, 2019
    Publication date: April 23, 2020
    Inventors: Colleen CUTCLIFFE, John S. EID, James H. Bullard, Marcus F. SCHICKLBERGER, Andrew T. CHENG, Orville G. KOLTERMAN, Tomer ALTMAN
  • Publication number: 20150174209
    Abstract: In alternative embodiments, the invention provides formulations, pharmaceutical compositions, devices and other products of manufacture comprising a therapeutically effective mixture of an insulin and a pramlintide, and methods for making and using them.
    Type: Application
    Filed: May 24, 2013
    Publication date: June 25, 2015
    Applicants: AMYLIN PHARMACEUTICALS. LLC, UVA PATENT FOUNDATION d/b/a THE UVA LICENSING AND VENTURES GROUP, GRUPPO BIOMED MOD
    Inventors: Elaine Chiquette, Kathrin Herrmann, David G. Maggs, Orville G. Kolterman, Jui-Chen Lin, Steven Shijun Ren, Li Jin, Claudio Cobelli, Boris Kovatchev
  • Publication number: 20150080308
    Abstract: Provided herein are formulations containing exendins, exendin agonists and/or exendin analogs and methods of using the exendins, exendin agonists and/or exendin analogs and formulations thereof to treat glucagonoma and necrolytic migratory erythema, or to suppress glucagon secretion.
    Type: Application
    Filed: November 25, 2014
    Publication date: March 19, 2015
    Inventors: Orville G. KOLTERMAN, Andrew A. YOUNG, James J. L'ITALIEN
  • Publication number: 20120196799
    Abstract: Methods for treating obesity are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist alone or in conjunction with another obesity relief agent. Additionally, methods for reducing insulin-induced weight gain are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist.
    Type: Application
    Filed: April 12, 2012
    Publication date: August 2, 2012
    Applicant: Amylin Pharmaceuticals, Inc.
    Inventors: Bradford J. DUFT, Orville G. Kolterman
  • Publication number: 20110281798
    Abstract: Novel formulations containing exendins, exendin agonists and/or exendin analogs are provided.
    Type: Application
    Filed: March 10, 2011
    Publication date: November 17, 2011
    Applicant: AMYLIN PHARMACEUTICALS, INC.
    Inventors: Orville G. KOLTERMAN, Andrew A. Young, James J. L'Italien
  • Patent number: 7910548
    Abstract: Methods for treating obesity are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist alone or in conjunction with another obesity relief agent.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: March 22, 2011
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Bradford J. Duft, Orville G. Kolterman
  • Patent number: 7906146
    Abstract: Novel formulations containing exendins, exendin agonists and/or exendin analogs are provided.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: March 15, 2011
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Orville G. Kolterman, Andrew A. Young, James J. L'Italien
  • Publication number: 20090215694
    Abstract: Novel formulations containing exendins, exendin agonists and/or exendin analogs are provided.
    Type: Application
    Filed: February 20, 2009
    Publication date: August 27, 2009
    Applicant: AMYLIN PHARMACEUTICALS, INC
    Inventors: Orville G. Kolterman, Andrew A. Young, James J. L'Italien
  • Publication number: 20080249018
    Abstract: Novel formulations containing exendins, exendin agonists and/or exendin analogs are provided
    Type: Application
    Filed: April 10, 2008
    Publication date: October 9, 2008
    Applicant: Amylin Pharmaceuticals, Inc.
    Inventors: Orville G. KOLTERMAN, Andrew A. YOUNG, James J. L'ITALIEN
  • Patent number: 7407934
    Abstract: Methods for treating conditions associated with elevated, inappropriate or undesired post-prandial blood glucose levels are disclosed which comprise administration of an effective amount of an amylin agonist alone or in conjunction with other anti-gastric emptying agents. Methods for reducing gastric motility and delaying gastric emptying for therapeutic and diagnostic purposes are also described.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: August 5, 2008
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Orville G. Kolterman, Andrew A. Young, Timothy J. Rink, Kathleen Ann Keating Brown
  • Patent number: 7399489
    Abstract: Novel formulations containing exendins, exendin agonists and/or exendin analogs are provided.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: July 15, 2008
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Orville G. Kolterman, Andrew A. Young, James J. L'Italien
  • Patent number: 6902744
    Abstract: Novel exendin and exendin agonist compound formulations and dosages and methods of administration thereof are provided. These compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: June 7, 2005
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Orville G. Kolterman, Andrew A. Young
  • Publication number: 20040097415
    Abstract: Methods for treating conditions associated with elevated, inappropriate or undesired post-prandial blood glucose levels are disclosed which comprise administration of an effective amount of an amylin agonist alone or in conjunction with other anti-gastric emptying agents. Methods for reducing gastric motility and delaying gastric emptying for therapeutic and diagnostic purposes are also described.
    Type: Application
    Filed: August 18, 2003
    Publication date: May 20, 2004
    Inventors: Orville G. Kolterman, Andrew A. Young, Timothy J. Rink, Kathleen Ann Keating Brown
  • Publication number: 20040022807
    Abstract: Methods for treating obesity are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist alone or in conjunction with another obesity relief agent. Additionally, methods for reducing insulin-induce weight gain are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist.
    Type: Application
    Filed: December 6, 1999
    Publication date: February 5, 2004
    Inventors: BRADFORD J DUFT, ORVILLE G KOLTERMAN
  • Patent number: 6608029
    Abstract: Methods for treating conditions associated with elevated, inappropriate or undesired post-prandial blood glucose levels are disclosed which comprise administration of an effective amount of an amylin agonist alone or in conjunction with other anti-gastric emptying agents. Methods for reducing gastric motility and delaying gastric emptying for therapeutic and diagnostic purposes are also described.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: August 19, 2003
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Orville G. Kolterman, Andrew A. Young, Timothy J. Rink, Kathleen Ann Keating Brown
  • Publication number: 20030130177
    Abstract: Methods of improving lipid profile, including methods for lowering fasting triglyceride levels and post-prandial triglyceride excursions are disclosed comprising administering an effective amount of an amylin or amylin agonist.
    Type: Application
    Filed: January 8, 2003
    Publication date: July 10, 2003
    Inventors: Orville G. Kolterman, Christian Weyer, David G. Maggs, Mark Fineman
  • Publication number: 20030087820
    Abstract: Novel exendin and exendin agonist compound formulations and dosages and methods of administration thereof are provided. These compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
    Type: Application
    Filed: May 28, 2002
    Publication date: May 8, 2003
    Inventors: Andrew A. Young, Orville G. Kolterman