Patents by Inventor Osama MAHMOUD

Osama MAHMOUD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF C-GLYCOSIDES OF INTEREST
    Publication number: 20230313248
    Abstract: The present invention relates to a biotechnological method for producing a C-glycoside of interest. The invention further relates to the use of a sialylated C-glycoside as a donor in an enzymatic glycosylation reaction. The present invention further relates to the following C- glycosides.
    Type: Application
    Filed: February 24, 2022
    Publication date: October 5, 2023
    Inventors: Ferenc Horvath, Györgyi Osztrovszky, Gyula Dekany, Agathe Bronikowski, Piroska Kovacs-Penzes, Rafael Soares, Jorge Santos, Fabio Pereira, Osama Mahmoud, Nagy Csaba, Dário Jorge Silva Neves
  • SYNTHESIS OF GLYCOSYL FLUORIDES
    Publication number: 20230098432
    Abstract: The present invention relates to a method for producing a glycosyl fluoride of interest, the method comprising providing an internalized exogenous precursor and a genetically modified cell, wherein one or more glycosylation reactions can be performed on the exogenous precursor in the genetically modified cell, the genetically modified cell comprising one or more nucleic acid sequences encoding one or more glycosyltransferase enzymes. The present invention further relates to a compound of the following formula: 2b.
    Type: Application
    Filed: February 24, 2021
    Publication date: March 30, 2023
    Inventors: Ferenc Horvath, Györgyi Osztrovszky, Gyula Dekany, Agathe Bronikowski, Piroska Kovacs-Penzes, Rafael Soares, Jorge Santos, Fabio Pereira, Osama Mahmoud, Nagy Csaba, Dário Jorge Silva Neves
  • SYNTHESIS OF GLYCOSYLATED SPHINGOID BASES OF INTEREST OR ANALOGUES THEREOF
    Publication number: 20230094369
    Abstract: The present invention relates to a method for producing a glycosylated sphingoid base of interest or an analogue thereof, the method comprising providing an internalized exogenous precursor and a genetically modified cell, wherein one or more glycosylation reactions can be performed on the exogenous precursor in the genetically modified cell, the genetically modified cell comprising one or more nucleic acid sequences encoding one or more glycosyltransferase enzymes.
    Type: Application
    Filed: February 24, 2021
    Publication date: March 30, 2023
    Inventors: Ferenc Horvath, Györgyi Osztrovszky, Gyula Dekany, Agathe Bronikowski, Piroska Kovacs-Penzes, Rafael Soares, Jorge Santos, Fabio Pereira, Osama Mahmoud, Nagy Csaba, Dário Jorge Silva Neves
  • MEANS AND METHODS FOR PRODUCING ISOBUTENE FROM ACETYL-COA
    Publication number: 20220145336
    Abstract: Described is a recombinant organism or microorganism which is capable of enzymatically converting acetyl-CoA into isobutene, (A) wherein in said organism or microorganism: (i) acetyl-CoA is enzymatically converted into acetoacetyl-CoA, (ii) acetoacetyl-CoA is enzymatically converted into 3-hydroxy-3-methylglutaryl-CoA, (iii) 3-hydroxy-3-methylglutaryl-CoA is enzymatically converted into 3-methylglutaconyl-CoA, (iv) 3-methylglutaconyl-CoA is enzymatically converted into 3-methylcrotonyl-CoA, and (v) wherein said 3-methylcrotonyl-CoA is converted into isobutene by: (a) enzymatically converting 3-methylcrotonyl-CoA into 3-methylcrotonic acid which is then further enzymatically converted into said isobutene; or (b) enzymatically converting 3-methylcrotonyl-CoA into 3-hydroxy-3-methylbutyryl-CoA which is then further enzymatically converted into 3-hydroxy-3-methylbutyric acid which is then further enzymatically converted into 3-phosphonoxy-3-methylbutyric acid which is then further enzymatically converted into sai
    Type: Application
    Filed: March 19, 2020
    Publication date: May 12, 2022
    Inventors: Romain CHAYOT, Maria ANISSIMOVA, Florence MARTIN, Florent COLLAS, Osama MAHMOUD