Abstract: The present invention provides an antisense oligonucleotide that is formed of 15-22 nucleotides and that is complementary to a nucleic acid including at least 15 consecutive bases in a specific target region of a base sequence of SEQ ID NO: 471, or a pharmaceutically acceptable salt thereof, or hydrates of those.

Abstract: A ridge filter 100 provided in a particle therapy system includes a repeating structure body 101 having a plurality of extending parts 101c extending along the incident direction P of a proton beam 204, and a bottom plate 102 provided on the lower face 101b side opposite to the incident side of the proton beam 204 of the repeating structure body 101. In addition, the repeating structure body 101 and the bottom plate 102 are integrally formed by a molding method, and each of the repeating structure body 101 and the bottom plate 102 is formed of a laminate of resin.

Abstract: A ridge filter 100 provided in a particle therapy system includes a repeating structure body 101 having a plurality of extending parts 101c extending along the incident direction P of a proton beam 204, and a bottom plate 102 provided on the lower face 101b side opposite to the incident side of the proton beam 204 of the repeating structure body 101. In addition, the repeating structure body 101 and the bottom plate 102 are integrally formed by a molding method, and each of the repeating structure body 101 and the bottom plate 102 is formed of a laminate of resin.

Abstract: A physical-layer unit carries out startup processing in response to a first reset signal delivered from a host, generates and outputs a second reset signal to a data control unit in consideration of time required for the startup processing, reads data for initial setting stored in a storage unit of the data control unit via a serial bus after a waiting time elapses, the waiting time being preset in consideration of the time required for the data control unit to start up in response to the second reset signal, and writes the read data for initial setting into a data register included in the physical layer unit.

Abstract: A peripheral device is detachably connected to a host device and includes: an electronic component that generates heat; an electrical connector for electrically connecting the electronic component to the host device; a heat transfer device having a first end thermally connected to the electronic component; and a heat transfer connector thermally connecting a second of the heat transfer device to the host device. The heat generated by the electronic component is discharged, or transferred, to the host device side through the heat transfer device and the heat transfer connector.

Abstract: A module has an IC for communication control (a PHY unit) and an EEPROM (or MCU) connected to the PHY unit via an I2C bus. When a software reset is triggered while the PHY unit reads non-volatile register (NVR) data from the EEPROM (or MCU) via the I2C bus, the module causes an I2C interface circuit of the PHY unit to forcedly toggle and send a clock signal to the EEPROM (or MCU) via the I2C bus to make the EEPROM (or MCU) recognize that interrupted communications via the I2C bus are pseudo completed.

Abstract: If an interrupt occurs due to an interrupt factor during a user program execution, a control program product for a microcomputer changes the operating frequency. The control program product then executes a subroutine and performs an operating frequency restoration process. The operating frequency restoration process is a common process that is also performed when another subroutine is executed.

Abstract: A peripheral device is detachably connected to a host device and includes: an electronic component that generates heat; an electrical connector for electrically connecting the electronic component to the host device; a heat transfer device having a first end thermally connected to the electronic component; and a heat transfer connector thermally connecting a second of the heat transfer device to the host device. The heat generated by the electronic component is discharged, or transferred, to the host device side through the heat transfer device and the heat transfer connector.

Abstract: When creating other tool path from two tool paths for cutting a work accurately and efficiently, the data on the first tool path is composed of a position vector and a direction vector of a tool for use when the work is cut while moving the tool. The data on the second tool path is composed of a position vector and a direction vector of the tool for use when the work, which has been cut according to the first tool path, is further cut. A computer uses the first tool path data and second tool path data to calculate a position vector and a direction vector of a medium tool path that is between the first tool path and second tool path.

Abstract: An optical communication module includes a physical-layer unit having a first control unit for receiving a write destination address and NVR data from a host via a serial bus, and for carrying out serial/parallel conversion of the received write destination address and NVR data, and storing them in registers of the first control unit, respectively, and a second control unit for copying the stored write destination address and NVR data to corresponding registers of the second control unit, respectively, and for carrying out parallel/serial conversion of the write destination address and NVR data which are copied to the registers of the second control unit, respectively, and sending them to either an EEPROM or a flash memory of a microcomputer, as well as a write command, via another serial bus to write the NVR data into either the EEPROM or the flash memory of the microcomputer.

Abstract: A module has an IC for communication control (a PHY unit) and an EEPROM (or MCU) connected to the PHY unit via an I2C bus. When a software reset is triggered while the PHY unit reads non-volatile register (NVR) data from the EEPROM (or MCU) via the I2C bus, the module causes an I2C interface circuit of the PHY unit to forcedly toggle and send a clock signal to the EEPROM (or MCU) via the I2C bus to make the EEPROM (or MCU) recognize that interrupted communications via the I2C bus are pseudo completed.

Abstract: A physical-layer unit carries out startup processing in response to a first reset signal delivered from a host, generates and outputs a second reset signal to a data control unit in consideration of time required for the startup processing, reads data for initial setting stored in a storage unit of the data control unit via a serial bus after a waiting time elapses, the waiting time being preset in consideration of the time required for the data control unit to start up in response to the second reset signal, and writes the read data for initial setting into a data register included in the physical layer unit.

Abstract: A numerically controlled curved-surface machining unit equipped with three linearly moving axes and, at least, one rotary axis, including a simultaneous multiple-axis control NC machine numerically controlled by a numerical control unit with a numerical control NURBS interpolation function. The unit enables reading, as CL (cutter location) data, tool control point vector data and tool axis vector data, along a machining direction on a workpiece coordinate system for a curved surface, obtaining feed rates therefor, and calculation by conversion of the CL data into position vectors of three linear axes on a machine coordinate system, rotation angles and feed rates on the machine coordinate system so as to operate the simultaneous multiple-axis control NC machine on the basis of a machine configuration of the simultaneous multiple-axis control NC machine.

Abstract: A numerically controlled curved-surface machining unit comprises a component converting matrix·angle-addition value forming function of converting CL (cutter location) data into components on a normal coordinate system on the basis of the machine configuration of the simultaneous multiple-axis control NC machine, a component converting function of converting from the workpiece coordinate system to the normal coordinate system, a function of forming second angles of a second rotary axis on the normal coordinate system, a compensating function of forming a continuous angle distribution from a distribution of the second angles, a function of forming first angles of a first rotary axis on a coordinate system rotated by the second angles at the second rotary axis, a compensating function of forming a continuous angle distribution from a distribution of the first angles, a machine coordinate transformation matrix forming function of obtaining a matrix for converting the tool control point vectors on the workpiece c

Abstract: When creating other tool path from two tool paths for cutting a work accurately and efficiently, the data on the first tool path is composed of a position vector and a direction vector of a tool for use when the work is cut while moving the tool. The data on the second tool path is composed of a position vector and a direction vector of the tool for use when the work, which has been cut according to the first tool path, is further cut. A computer uses the first tool path data and second tool path data to calculate a position vector and a direction vector of a medium tool path that is between the first tool path and second tool path.

Abstract: A data table includes a source pointer indicating a starting address of drawing data, a destination pointer indicating a destination of drawing data to be transferred, and a data length indicating a data length of drawing data to be transferred. Data table may indicate drawing data to be drawn. Thus frames may share drawing data. As such the amount of drawing data can be reduced.

Abstract: A numerically controlled curved-surface machining unit comprises a component converting matrix•angle-addition value forming function of converting CL (cutter location) data into components on a normal coordinate system on the basis of the machine configuration of the simultaneous multiple-axis control NC machine, a component converting function of converting from the workpiece coordinate system to the normal coordinate system, a function of forming second angles of a second rotary axis on the normal coordinate system, a compensating function of forming a continuous angle distribution from a distribution of the second angles, a function of forming first angles of a first rotary axis on a coordinate system rotated by the second angles at the second rotary axis, a compensating function of forming a continuous angle distribution from a distribution of the first angles, a machine coordinate transformation matrix forming function of obtaining a matrix for converting the tool control point vectors on the workpiece c

Abstract: A graphic accelerator includes an image-forming data decode unit, an image memory control unit and a screen data generation unit. The image memory control unit performs a control for writing an output of the image-forming data decode unit to a frame buffer and reading out information stored in the frame buffer. Screen data generation unit restores (interpolates) the color information based on the data read out from the frame buffer and generates screen data. In the frame buffer the information for each pixel is stored in a deleted form including two types of color information among three types of color information consisting of R, G and B. At the reading, the deleted color information is interpolated with the color information of other pixel.

Abstract: When a serial external interface receives a port address from a host device, a CPU reads data at all device addresses corresponding to the port address from a secondary storage medium and writes the data to a primary storage medium. When receiving a device address from host device, serial external interface transmits the data stored in primary storage medium and corresponding to the device address to host device. Therefore, it is possible to transmit the data to host device in short time after receiving the lowest address.