Patents by Inventor Osamu Ikehara

Osamu Ikehara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150313889
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: July 14, 2015
    Publication date: November 5, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka TOKUMASU, Tamotsu SUZUKI, Takahiro KOSHIBA, Koji OHSUMI, Osamu IKEHARA, Yuko KODAMA
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9115107
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 25, 2015
    Assignee: AJINOMOTO CO., INC.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150011511
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: September 25, 2014
    Publication date: January 8, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka TOKUMASU, Tamotsu SUZUKI, Takahiro KOSHIBA, Koji OHSUMI, OSAMU IKEHARA, Yuko KODAMA
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 8877805
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: November 4, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20140080790
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 8609715
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: December 17, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20120283222
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: May 31, 2012
    Publication date: November 8, 2012
    Applicant: Ajinomoto Co., Inc.
    Inventors: Atsushi KONISHI, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • Acylamide compounds having secretagogue or inducer activity of adiponectin
    Patent number: 7732637
    Abstract: The present invention provides an acylamide compound of the following formula (1), prodrugs thereof, or pharmaceutically acceptable salts thereof; and an adiponectin inducer or secretagogue, therapeutic agent of metabolic syndromes, therapeutic agent of hypoadiponectinemia, therapeutic agent of hyperlipemia, preventive/therapeutic agent of diabetes, improving agent of impaired glucose tolerance, improving agent of insulin resistance, enhancing agent of insulin sensitivity, therapeutic agent of hypertension, preventive/therapeutic agent of vascular disorders, an anti-inflammatory agent, therapeutic agent of hepatic inflammation, therapeutic agent of fatty liver, therapeutic agent of hepatic fibrosis, therapeutic agent of liver cirrhosis, preventive/therapeutic agent of non-alcoholic/nonviral steatohepatitis (NASH) or non-alcoholic/nonviral fatty liver disease (NAFLD), or therapeutic agent of obesity, each of which has the above compounds as an active ingredient.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: June 8, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Katsumi Maezono, Toshihiko Yoshimura, Nozomu Ishida, Naoyuki Fukuchi, Toshihiro Hatanaka, Osamu Ikehara, Yayoi Kawato, Hideyuki Tanaka
  • ACYLAMIDE COMPOUNDS HAVING SECRETAGOGUE OR INDUCER ACTIVITY OF ADIPONECTIN
    Publication number: 20100063151
    Abstract: The present invention provides acylamide compounds, prodrugs thereof, or pharmaceutically acceptable salts thereof; and an adiponectin inducer or secretagogue, and therapeutic methods by administering the same.
    Type: Application
    Filed: November 18, 2009
    Publication date: March 11, 2010
    Applicant: Ajinomoto Co., Inc.
    Inventors: Katsumi MAEZONO, Toshihiko YOSHIMURA, Nozomu ISHIDA, Naoyuki FUKUCHI, Toshihiro HATANAKA, Osamu IKEHARA, Yayoi KAWATO, Hideyuki TANAKA
  • ACYLAMIDE COMPOUNDS HAVING SECRETAGOGUE OR INDUCER ACTIVITY OF ADIPONECTIN
    Publication number: 20070282002
    Abstract: The present invention provides an acylamide compound of the following formula (1), prodrugs thereof, or pharmaceutically acceptable salts thereof; and an adiponectin inducer or secretagogue, therapeutic agent of metabolic syndromes, therapeutic agent of hypoadiponectinemia, therapeutic agent of hyperlipemia, preventive/therapeutic agent of diabetes, improving agent of impaired glucose tolerance, improving agent of insulin resistance, enhancing agent of insulin sensitivity, therapeutic agent of hypertension, preventive/therapeutic agent of vascular disorders, an anti-inflammatory agent, therapeutic agent of hepatic inflammation, therapeutic agent of fatty liver, therapeutic agent of hepatic fibrosis, therapeutic agent of liver cirrhosis, preventive/therapeutic agent of non-alcoholic/nonviral steatohepatitis (NASH) or non-alcoholic/nonviral fatty liver disease (NAFLD), or therapeutic agent of obesity, each of which has the above compounds as an active ingredient.
    Type: Application
    Filed: August 7, 2007
    Publication date: December 6, 2007
    Applicant: AJINOMOTO CO. INC
    Inventors: Katsumi MAEZONO, Toshihiko Yoshimura, Nozomu Ishida, Naoyuki Fukuchi, Toshihiro Hatanaka, Osamu Ikehara, Yayoi Kawato, Hideyuki Tanaka