Abstract: The present invention provides a new compound having excellent safety which can be used as an anti-inflammatory agent, an anti-cancer agent against lung cancer, and the like. The compound or the salt thereof of the present invention is a compound represented by Formula (A) or Formula (B): where: X1 is a hexose or a hydroxyl group, and X2 is a phosphate group or a hydroxyl group.

Abstract: A method for analyzing a structure of a substance of interest uses triple-quadrupole mass spectrometry (TQ-MS), and allows for acquisition of MSn information from data resulting from the TQ-MS measurement. The method includes (a) performing a measurement of triple quadrupole mass spectrometry with respect to the substance of interest while varying a value of CID energy; (b) at given values of CID energy, calculating percentages of precursor ion contents to a total ion content, and percentages of product ion contents to the total ion content; (c) extracting values of the percentages of product ion contents to the total ion content, wherein said values are values of the percentages of product ion contents at the respective values of CID energy; and (d) calculating sums of all combinations of the values of the percentages of product ion contents to the total ion content extracted in step (c).

Abstract: A method for analyzing a structure of a substance of interest uses triple-quadrupole mass spectrometry (TQ-MS), and allows for acquisition of MSn information from data resulting from the TQ-MS measurement. The method includes (a) performing a measurement of triple quadrupole mass spectrometry with respect to the substance of interest while varying a value of CID energy; (b) at given values of CID energy, calculating percentages of precursor ion contents to a total ion content, and percentages of product ion contents to the total ion content; (c) extracting values of the percentages of product ion contents to the total ion content, wherein said values are values of the percentages of product ion contents at the respective values of CID energy; and (d) calculating sums of all combinations of the values of the percentages of product ion contents to the total ion content extracted in step (c).

Abstract: It is an objective of the present invention to provide a method of analyzing the structure of a sugar chain by performing CID-MSn measurement of a sugar chain of unknown structure and comparing the obtained data with obtained reference data acquired in advance.

Abstract: The present invention provides a compound represented by the formula (I) or a salt thereof: wherein R1 represents a hydrogen atom, a C1-10 alkyl group optionally having a substituent, or a protecting group of N; R2 represents a C1-10 alkyl group optionally having a substituent or a C2-10 alkenyl group optionally having a substituent; R3 and R4 independently represent a hydrogen atom or a protecting group of hydroxyl group; X represents —N(R5)R6 or a residue of amino acid or of an amino group of a peptide wherein R5 and R6 independently represent a hydrogen atom, a C1-10 alkyl group optionally having a substituent, or a C3-12 cycloalkyl group optionally having a substituent; and Y represents a hydrogen atom, —CH2NH2, —CONH2, or —COOH. The compound of the present invention is useful as a specific inhibitor of sugar chain related enzymes such as glycosyltransferase and glycosidase, and is useful as, for example, a medicine for treating or preventing diseases associated with sugar chain related enzymes.

Abstract: An object of the present invention is to provide a method for efficiently chemically synthesizing biomolecules including a nucleotide (nucleic acid), a peptide (protein), or a sugar chain, as representative examples. The present invention provides a method of solid-phase synthesis of sugar chain(s) for synthesizing multiple types of sugar chains in at least one sugar chain synthesis reaction system comprising multiple types of monosaccharide units, which is characterized in that it comprises changing the temperature in the sugar chain synthesis reaction system depending on the temperature rising rate that has been determined based on a decrease in side reaction(s) in the reaction system as an indicator.

Abstract: The present invention provides a compound represented by the formula (I) or a salt thereof: 1

Abstract: A medicament for treatment of a viral infection which comprises as an active ingredient a compound represented by the following formula (I) or its Pharmaceutically acceptable salt, or a hydrate thereof or a solvate thereof.

Abstract: A polymer compound or a salt thereof which comprises a biodegradable polymer such as polyglutamic acid acetylated at N-terminal thereof containing a glycosphingolipid such as lysoganglioside GM3, and which exerts antiviral activity against variety of viruses and is useful as an active ingredient of a medicament.