Patents by Inventor Osamu Miyashita

Osamu Miyashita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040266423
    Abstract: A test apparatus main body mounted in a single housing has a connection unit, a common bus, terminal control units, measurement units, and a total control unit. The connection unit can connect at least two terminals of identical or different type of communication systems. The terminal control units output test signals including signals that respectively control the terminals which can be connected to the connection unit based on predetermined test programs according to the type of communication systems, and measurement instructions, which are supplied via the common bus. The second measurement units perform measurements designated by the measurement instructions upon reception of response signals which are output from the terminals in response to the test signals from the terminal control units.
    Type: Application
    Filed: June 10, 2004
    Publication date: December 30, 2004
    Applicant: Anritsu Corporation
    Inventors: Takayuki Morikawa, Tsuyoshi Doi, Osamu Miyashita
  • Patent number: 4961692
    Abstract: The present invention provides a pump by vessel oscillation including a vessel having an inlet for liquid and an outlet opening in a specific tangential direction of an outer peripheral portion thereof. The vessel is oscillated in a specific direction to outflow the liquid through the outlet opening. Accordingly, the liquid in the interior of the vessel undergoes a simple centrifugal motion and when the pump is used for a blood circulation device such as an artificial heart or assisted circulation device, the blood is completely shut off from outside and isolated from entry of various germs, air, foreign matter, etc. The pump is simple is construction and excellent in reliability and durability.
    Type: Grant
    Filed: May 16, 1989
    Date of Patent: October 9, 1990
    Inventors: Yasuhiro Fukui, Osamu Miyashita
  • Patent number: 4869650
    Abstract: The present invention provides a pump by vessel oscillation including a vessel having an inlet for liquid and an outlet opening in a specific tangential direction of an outer peripheral portion thereof. The vessel is oscillated in a specific direction to outflow the liquid through the outlet opening. Accordingly, the liquid in the interior of the vessel undergoes a simple centrifugal motion and when the pump is used for a blood circulation device such as an artificial heart or assisted circulation device, the blood is completely shut off from outside and isolated from entry of various germs, air, foreign matter, etc. The pump is simple in construction and excellent in reliability and durability.
    Type: Grant
    Filed: April 22, 1988
    Date of Patent: September 26, 1989
    Inventors: Yasuhiro Fukui, Osamu Miyashita
  • Patent number: 4329460
    Abstract: New derivatives of the formula: ##STR1## (wherein X is O or NH; R.sub.1 is --OH which may optionally be etherified or esterified, etherified mercapto or --NH.sub.2 which may optionally be substituted; R.sub.2 and R.sub.3, respectively, mean H, lower alkyl or ##STR2## and Y is an esterified or amidated carboxyl group, or CN). These derivatives are produced, by fluorination of corresponding 1,2,3,4-tetrahydro-2,4-dioxopyrimidine compounds and can be converted into 5-fluorouracil derivatives under hydrolytic conditions. The new derivatives are able to prolong the lives of animals having carcinomas or have antiviral activity.
    Type: Grant
    Filed: June 13, 1979
    Date of Patent: May 11, 1982
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Koichi Matsumura, Hiroshi Shimadzu, Naoto Hashimoto
  • Patent number: 4317821
    Abstract: Novel maytansinoids of the formula: ##STR1## wherein Y is H or Cl, and R is C.sub.2-15 alkyl, phenyl-C.sub.1-4 alkyl, pyridyl-C.sub.1-4 alkyl, imidazolyl-C.sub.1-4 alkyl, indolyl-C.sub.1-4 alkyl, furyl-C.sub.1-4 alkyl or thienyl-C.sub.1-4 alkyl, said R group being substituted by hydroxyl, halogen or C.sub.1-5 alkanoyloxy at its .alpha.- and/or .beta.-position, have antimitotic, antitumor and antimicrobial activities.
    Type: Grant
    Filed: May 22, 1980
    Date of Patent: March 2, 1982
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4309428
    Abstract: Novel maytansinoids of the formula: ##STR1## wherein X is hydrogen or chlorine,R.sup.1 is C.sub.2-4 alkyl,R.sup.2 is C.sub.2-8 alkyl which may be substituted or methyl which is substituted,have antimicrobial, antimitotic and antitumor activities.
    Type: Grant
    Filed: July 23, 1980
    Date of Patent: January 5, 1982
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4308268
    Abstract: Novel maytansinoids of the formula: ##STR1## wherein X is H or Cl, and Y is Cl, OH, SH, CN, NO.sub.2, --OR or --S(O).sub.n R wherein R is slkyl, aryl, aralkyl or azaheterocyclic group which may be substituted, and n is 0, 1 or 2, have antimitotic, antitumor and antimicrobial activities.
    Type: Grant
    Filed: May 28, 1980
    Date of Patent: December 29, 1981
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4308269
    Abstract: Novel maytansinoids of the formula: ##STR1## wherein X is H or Cl, and R is a hydrocarbon residue or an azaheterocyclic group, said R group having at least one of water-solubilizing substituents, have antimitotic, antitumor and antimicrobial activities.
    Type: Grant
    Filed: June 6, 1980
    Date of Patent: December 29, 1981
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4264596
    Abstract: Novel maytansinoid compounds of the formula: ##STR1## wherein X is H or Cl, R.sup.1 is an alkyl group of 2 to 4 carbon atoms and R.sup.2 is a lower alkyl group or an unsubstituted or substituted phenyl or aralkyl group, have antimitotic, antitumor and antimicrobial activities.
    Type: Grant
    Filed: July 23, 1980
    Date of Patent: April 28, 1981
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4263294
    Abstract: Novel maytansinoids of the formula: ##STR1## wherein X is H or Cl, and R is ##STR2## wherein R.sup.1 and R.sup.2 may be the same or different, and each is H or a substituted or unsubstituted hydrocarbon residue or heterocyclic group, or R.sup.1 and R.sup.2 may, taken together with the adjacent N atom, form a heterocyclic group, andR.sup.3 is a substituted or unsubstituted hydrocarbon residue, have antimitotic, antitumor and antimicrobial activities.
    Type: Grant
    Filed: November 13, 1979
    Date of Patent: April 21, 1981
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4260608
    Abstract: Novel maytansinoids of the formula: ##STR1## wherein R.sup.1 is hydrogen atom, an alkyl group which may optionally be substituted or a group of the formula: --A.sup.1 --Y.sup.1 wherein A.sup.1 is an alkylene group or a bond, and Y.sup.1 is a cycloalkyl, phenyl, indolyl or imidazolyl group which may optionally be substituted,R.sup.2 is hydrogen atom, an alkyl, cycloalkyl or benzyl group,R.sup.3 is hydrogen atom, an alkyl group which may optionally be substituted, alkoxy, bornyloxy, isobornyloxy, benzyloxy group or a group of the formula: --A.sup.2 --Y.sup.2 wherein A.sup.2 is an alkylene group or a bond, and Y.sup.2 is an alicyclic hydrocarbon, phenyl or heterocyclic group which may optionally be substituted,provided that R.sup.3 is not an unsubstituted C.sub.1-4 alkyl group when both R.sup.1 and R.sup.2 are methyl groups, have antimicrobial antimitotic and antitumor activities.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: April 7, 1981
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4256746
    Abstract: Novel dechloromaytansinoids of the formula: ##STR1## wherein R is H or acyl having 1 to 20 carbon atoms, have antimitotic, antitumor and antimicrobial activities.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: March 17, 1981
    Assignee: Takeda Chemical Industries
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4248870
    Abstract: Novel maytansinoids of the formula: ##STR1## wherein R is an alicyclic hydrocarbon group of 3 to 10 carbon atoms, phenyl or heterocyclic group, which may optionally be substituted, andA is an alkylene group of 1 to 4 carbon atoms or a bond, provided that A means said alkylene group when attached to a N atom in said heterocyclic group R,have antimicrobial, antimitotic and antitumor activities.
    Type: Grant
    Filed: October 18, 1979
    Date of Patent: February 3, 1981
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Hiroshi Akimoto
  • Patent number: 4190656
    Abstract: New compounds of the formula ##STR1## (wherein R.sub.1 represents a lower alkyl group: and ##STR2## represents an alkylidene radical in which at least one of R.sub.2 and R.sub.3 is a lower alkyl which may optionally be substituted by phenyl, phenyl or a 5- or 6-membered aromatic ring including S, N or O, and the remainder, if any, is hydrogen; ora cycloalkylidene radical of up to six carbon atoms, to which a benzene ring may optionally be fused).These compounds are produced by reacting the corresponding 6-acyloxy compounds with a compound of the formula ##STR3## The new compounds have antiviral activity and are useful to prolong the life spans of tumor-bearing animals.
    Type: Grant
    Filed: September 22, 1978
    Date of Patent: February 26, 1980
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Koichi Matsumura, Osamu Miyashita, Hiroshi Shimadzu, Naoto Hashimoto
  • Patent number: 4052391
    Abstract: Novel 3-(disubstituted)aminoisothiazolo[3,4-d]pyrimidines of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are respectively alkyl, alkenyl, aryl, aralkyl or aralkenyl, each of which may be substituted, or R.sup.1 and R.sup.2 form together with the adjacent nitrogen a heterocyclic ring which may be substituted, R.sup.4 is hydrogen or alkyl and X is oxygen or imino with a proviso that when X is imino R.sup.4 is hydrogen, show an eminent adenosine-3',5'-cyclic phosphate phosphodiesterase-inhibitory activity, and exhibit excellent pharmacological actions such as anti-inflammatory and sedative activities.
    Type: Grant
    Filed: March 3, 1976
    Date of Patent: October 4, 1977
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yoshiyasu Furukawa, Osamu Miyashita
  • Patent number: 3959280
    Abstract: Novel 3-(disubstituted)aminoisothiazolo[3,4-d]-pyrimidines of the formula ##SPC1##Wherein R.sup.1, R.sup.2 and R.sup.3 are respectively alkyl, alkenyl, aryl, aralkyl or aralkenyl, each of which may be substituted, or R.sup.1 and R.sup.2 form together with the adjacent nitrogen a heterocyclic ring which may be substituted, R.sup.4 is hydrogen or alkyl and X is oxygen or imino with a proviso that when X is imino R.sup.4 is hydrogen, show an eminent adenosine-3',5'-cyclic phosphate phosphodiesterase-inhibitory activity, and exhibit excellent pharmacological actions such as antiinflammatory and sedative activities.
    Type: Grant
    Filed: November 11, 1974
    Date of Patent: May 25, 1976
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yoshiyasu Furukawa, Osamu Miyashita