Patents by Inventor Osamu Miyazaki
Osamu Miyazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250235106Abstract: There are provided an information processing apparatus, an information processing method, and a program which can acquire a tomographic image at an appropriate imaging position according to a body type of a subject. The information processing apparatus includes at least one processor. The processor derives a determination target position of a subject in a body axis direction on the basis of body information indicating a physical feature of the subject in a predetermined range along the body axis direction of the subject, derives a reference position of the subject in the body axis direction on the basis of a subject image that is an image captured for the subject, and determines an imaging position of a tomographic image on the basis of a relative positional relationship between the determination target position and the reference position.Type: ApplicationFiled: January 13, 2025Publication date: July 24, 2025Applicant: FUJIFILM CorporationInventors: Atsushi INOUE, Osamu MIYAZAKI, Xinran ZHANG, Takashi SHIRAHATA, Koji YAMAGUCHI
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Publication number: 20250155453Abstract: The present invention provides an immunological detection method for trimeric type I collagen N-terminal propeptide in a biological sample, which uses a first antibody that binds to a first specific portion of a pro-al chain in the trimeric type I collagen N-terminal propeptide and a second antibody that binds to a second specific portion of a pro-al chain in the trimeric type I collagen N-terminal propeptide. The immunological detection method is easy to handle and can specifically (selectively) measure the trimer in biological samples containing the trimer and monomer of the ?-chain of PINP.Type: ApplicationFiled: March 22, 2023Publication date: May 15, 2025Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Shiomi HORIUCHI MORISHITA, Rikako OGASAWARA, Ryo SAHARA, Tomohide ASAI, Osamu MIYAZAKI
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Publication number: 20250130242Abstract: The present invention provides an immunological detection method for trimeric type I collagen N-terminal propeptide in a biological sample, which uses a first antibody that binds to a specific portion of a pro-?1 chain in the trimeric type I collagen N-terminal propeptide and a second antibody that binds to a specific portion of a pro-?2 chain in the trimeric type I collagen N-terminal propeptide. The immunological detection method is easy to handle and can specifically (selectively) measure the trimer in biological samples containing the trimer and monomer of the ?-chain of PINP.Type: ApplicationFiled: March 22, 2023Publication date: April 24, 2025Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Shiomi HORIUCHI MORISHITA, Rikako OGASAWARA, Ryo SAHARA, Tomohide ASAI, Osamu MIYAZAKI
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Publication number: 20250035618Abstract: It is an object of the present invention to provide a method for suppressing non-specific reactions using a highly versatile method without affecting specific reactions. The present invention provides a detection method for detecting a target antigen in a sample using a specific antibody that specifically binds to the antigen, the method comprising: a) a step of bringing the sample into contact with a modified antibody; and b) a step of bringing the sample into contact with the specific antibody simultaneously with or after the step a), which is a highly versatile method that can suppress non-specific reactions.Type: ApplicationFiled: December 27, 2022Publication date: January 30, 2025Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Daisuke YAMADA, Ikumi SUZUKI, Kengo FUJIMURA, Tomohide ASAI, Osamu MIYAZAKI
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Publication number: 20240343338Abstract: A front fork (1) includes: a fork main body (2) that includes a tube member (3) including a vehicle body side tube (3a) and an axle side tube (3b), and a suspension spring (4) that biases the tube member (3) in a stretching direction; a cap (5) that includes a cylindrical portion (5a) and a lid portion (5b) continuing to the outer circumference of the cylindrical portion (5a), and closes the opening end of the vehicle body side tube (3a); a washer (6) that supports the upper end of the suspension spring (4); an adjuster (7) that includes a shaft portion (7a) screwed to the washer (6), a flange portion (7b) provided at the rear end of the shaft portion (7a), and an operation shaft portion 7c extending from an opposite shaft portion side of the flange portion (7b), and that is rotatably inserted into the cylindrical portion 5a; and a stopper member (8) that is placed on the inner circumference of the cylindrical portion (5a) and prevents the adjuster (7) from being detached from the cap (5).Type: ApplicationFiled: December 20, 2021Publication date: October 17, 2024Applicant: KYB Motorcycle Suspension Co.,Ltd.Inventors: Osamu MIYAZAKI, Kei SUZAKI
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Publication number: 20240125784Abstract: The problem addressed by the present invention is to provide an immunological assay method using a monoclonal antibody and a kit including the monoclonal antibody, which can be used for assaying ICTP without requiring special facilities. This problem can be solved by a method for immunological assay of type I collagen C-terminal telopeptide in a biological sample, including contacting type I collagen C-terminal telopeptide with a monoclonal antibody that recognizes an amino acid sequence represented by GFDFSFLP (SEQ ID NO: 1) as an epitope.Type: ApplicationFiled: March 23, 2022Publication date: April 18, 2024Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Shiomi HORIUCHI MORISHITA, Rikako OGASAWARA, Tomohide ASAI, Osamu MIYAZAKI
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Publication number: 20230025583Abstract: A problem to be solved by the invention is to improve the sensitivity of measurement of an analyte in a sample by a sandwich immunoassay. The sensitivity can be improved significantly in a sandwich immunoassay using a first antibody and a second antibody when one or both of the first antibody and the second antibody are a mixture of a monoclonal antibody recognizing a linear epitope and a monoclonal antibody recognizing a conformational epitope.Type: ApplicationFiled: November 27, 2020Publication date: January 26, 2023Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Tomohide ASAI, Yoshihiro TANAKA, Ikumi SUZUKI, Satoko SEO, Tomoyuki USUI, Tomo SHIMIZU, Osamu MIYAZAKI
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Publication number: 20220170917Abstract: A problem to be solved is to perform an immunoassay method for BG in a biological sample having a sensitivity equivalent to and a reactivity similar to a Limulus amebocyte lysate reagent. The problem can be solved by an immunoassay method for ?-D-glucan in a biological sample, comprising assaying ?-D-glucan in the biological sample by using a monoclonal antibody binding to (1?3)-?-D-glucan having a degree of polymerization of 4.Type: ApplicationFiled: March 6, 2020Publication date: June 2, 2022Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Ei-ichiro SUNAMURA, Osamu MIYAZAKI, Takuya YOTANI, Shinichiro KITAHARA, Manami IWASAKI
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Publication number: 20210389306Abstract: A problem to be solved is to provide a glycated hemoglobin (%) assay method and assay reagent capable of accurate measurement of glycated hemoglobin (%) in blood even when a blood specimen containing hemoglobin contains abnormal hemoglobin such as HbS or HbC. The present invention provides a method capable of accurate measurement of glycated hemoglobin (%) in blood even in a specimen containing abnormal hemoglobin by combining two types of monoclonal antibodies, i.e., an anti-glycated hemoglobin monoclonal antibody and a monoclonal antibody to the anti-glycated hemoglobin monoclonal antibody, and an assay reagent for performing the method.Type: ApplicationFiled: September 27, 2019Publication date: December 16, 2021Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Mieko OTA, Osamu MIYAZAKI, Satoko SEO, Mitsuaki YAMAMOTO, Tomohisa NISHIO
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Publication number: 20210017564Abstract: What is required is a method of producing, without treating a glycoprotein in a biological sample with a denaturing agent in advance, a selectively binding material, which specifically reacts with a glycan of a glycoprotein, a selectively binding material such as antibody thus produced by the method, and a method of specifically detecting a glycoprotein by using the selectively binding material. In order to solve the problems, the present invention produces a selectively binding material specifically reactive with a glycan of a glycoprotein by treating the glycoprotein with a glycan-specific glycan-cleaving enzyme.Type: ApplicationFiled: September 29, 2020Publication date: January 21, 2021Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Tomohiro MIURA, Tomo SHIMIZU, Osamu MIYAZAKI
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Publication number: 20210017263Abstract: The antigen specificity of the antibody that recognizes a glycan antigen and is used as a tumor marker is not sufficient, and it has been a drawback that tumor marker detection using such an antibody is low in detection specificity, thereby deteriorating accuracy of cancer diagnosis. To solve the object described above, the present invention provides an antibody specifically reactive with a glycan of DUPAN-2 antigen for use as a tumor marker, and a production method thereof.Type: ApplicationFiled: March 29, 2019Publication date: January 21, 2021Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Tomohiro MIURA, Osamu MIYAZAKI
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Publication number: 20210017290Abstract: The antigen specificity of the antibody that recognizes a glycan antigen and is used as a tumor marker is not sufficient, and it has been a drawback that tumor marker detection using such an antibody is low in detection specificity, thereby deteriorating accuracy of cancer diagnosis. To solve the object described above, the present invention provides an antibody specifically reactive with a glycan of NCC-ST-439 antigen for use as a tumor marker, and a production method thereof.Type: ApplicationFiled: March 29, 2019Publication date: January 21, 2021Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Tomohiro MIURA, Osamu MIYAZAKI
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Publication number: 20200017582Abstract: The present invention is intended to enable detection of specific human BNP fragments solely by immunoassay, and, through a ratio measurement of the human BNP fragments, provides a convenient way of providing information useful for diagnosis and prognosis of heart disease. The invention achieves this by providing an assay that uses an antibody specific to human BNP fragment (4-32)—a fragment that has not caught much attention in the past. Provided herein is an immunoassay method for human BNP fragment (4-32) in a sample, and the method uses an antibody that reacts with human BNP fragment (4-32) but does not react with full-length human BNP (1-32), human BNP fragment (3-32), and human BNP fragment (5-32). Also provided herein is an assay in which the antibody is an antibody that reacts with human BNP fragment (4-32) at a site containing the N-terminus, and that reacts with human BNP fragment (4-10).Type: ApplicationFiled: October 18, 2017Publication date: January 16, 2020Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Tomo SHIMIZU, Osamu MIYAZAKI, Toru SUZUKI
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Publication number: 20160311895Abstract: Provided is a general-purpose technique capable of measuring the HbA1c content, which is comparable to the IFCC reference method. An antibody which reacts with a peptide or a protein having an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not react with a peptide or a protein in which the N-terminal valine of the relevant polypeptide or protein is modified.Type: ApplicationFiled: July 13, 2016Publication date: October 27, 2016Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Osamu MIYAZAKI, Kohei TAKUBO, Syunsuke KURASHITA
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Publication number: 20160313301Abstract: A method for determining sensitivity of a tumor to a HSP90 inhibitor, including: measuring a phosphorylation level of Akt or a phosphorylation level of ERK in a tissue of the tumor from a patient.Type: ApplicationFiled: December 3, 2014Publication date: October 27, 2016Inventors: Tsuyoshi FUKUDA, Osamu MIYAZAKI, Kuniko MASUDA, Kazuya OKAMOTO
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Patent number: 9341633Abstract: There are provided a pre-treatment technique for a glycated hemoglobin-containing sample, which is a simple and convenient treatment, is free from problems in storage stability and environmental aspects, and is capable of exposing an epitope sufficiently in a short time; and an method for an immunological assay of glycated hemoglobin using this technique. A method for pre-treating a glycated hemoglobin-containing sample for an immunological assay of glycated hemoglobin, the method includes treating a glycated hemoglobin-containing sample with a pre-treatment solution containing (A) guanidine or a salt thereof and (B) a nonionic surfactant and/or a nitrite.Type: GrantFiled: December 10, 2009Date of Patent: May 17, 2016Assignee: SEKISUI MEDICAL CO., LTD.Inventors: Osamu Miyazaki, Syunsuke Kurashita, Kohei Takubo
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Publication number: 20160129117Abstract: The purpose of the present invention is to avoid side effects from contained medicines. Provided are: a preparation obtained by mixing a boronic acid compound and a block copolymer represented by general formula (I); and a production method therefor.Type: ApplicationFiled: June 27, 2014Publication date: May 12, 2016Inventors: Masatoshi Abe, Masaharu Nakamura, Osamu Miyazaki, Keiko Sekine
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Publication number: 20160009794Abstract: Provided is a general-purpose technique capable of measuring the HbA1c content, which is comparable to the IFCC reference method. An antibody which reacts with a peptide or a protein having an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not react with a peptide or a protein in which the N-terminal valine of the relevant polypeptide or protein is modified.Type: ApplicationFiled: August 5, 2015Publication date: January 14, 2016Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Osamu MIYAZAKI, Kohei Takubo, Syunsuke Kurashita
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Patent number: 9208582Abstract: An image analysis system that analyzes an image of an object's organ having an anatomically symmetric shape includes: an image data read means that reads image data of the organ, a memory means that is connected to the image data read means, and stores the read image data, a display means that is connected to the memory means, and displays the image data as an image, a centerline setting means that is connected to the memory means, and sets a centerline of the organ in the image displayed on the display means, a region-of-interest setting means that is connected to the memory means, and uses the centerline to set a plurality of or at least one pair of regions of interest at anatomically symmetric opposite positions in the image of the organ, and an input means that is connected to the region-of-interest setting means, and inputs conditions for setting of the regions of interest in the image.Type: GrantFiled: October 31, 2006Date of Patent: December 8, 2015Assignee: HITACHI MEDICAL CORPORATIONInventors: Yasuo Omi, Ryo Takagi, Osamu Miyazaki, Yoshiaki Sugaya
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Patent number: 9169320Abstract: Provided is a general-purpose technique capable of measuring the HbA1c content, which is comparable to the IFCC reference method. An antibody which reacts with a peptide or a protein having an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not react with a peptide or a protein in which the N-terminal valine of the relevant polypeptide or protein is modified.Type: GrantFiled: December 10, 2009Date of Patent: October 27, 2015Assignee: SEKISUI MEDICAL CO., LTD.Inventors: Osamu Miyazaki, Kohei Takubo, Syunsuke Kurashita