Patents by Inventor Osamu Nakanishi
Osamu Nakanishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8026239Abstract: A method of treating a malignant tumor selected from the group consisting of leukemia, colorectal cancer, ovarian cancer, oral cancer, lung carcinoma, breast carcinoma, prostate carcinoma, and melanoma by administering to a patient in need thereof an effective amount of at least one compound represented by formula (1) wherein A, X, Q, R1-3, and n are defined herein.Type: GrantFiled: March 11, 2010Date of Patent: September 27, 2011Assignee: Bayer Schering Pharma AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
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Patent number: 7839020Abstract: An electric power supply system which, in the event of a power failure, is capable of efficiently supplying electric power to household electric appliances in cooperation of a vehicle, including a mechanism supplying electric power outside the vehicle, with a stationary fuel cell system and also includes an electric power supply system using a power converter for converting direct current powers from a vehicle fuel cell and a stationary fuel cell into alternating current powers. The electric power supply system is constructed by a vehicle fuel cell provided on a fuel cell vehicle, a stationary fuel cell provided in a stationary power supply system, and a power converter for converting direct current powers from the vehicle fuel cell and the stationary fuel cell into alternating current powers.Type: GrantFiled: April 21, 2006Date of Patent: November 23, 2010Assignee: Toyota Jidosha Kabushiki KaishaInventor: Osamu Nakanishi
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Publication number: 20100256201Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: ApplicationFiled: March 11, 2010Publication date: October 7, 2010Applicant: Bayer Schering Pharma AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
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Patent number: 7687525Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: GrantFiled: November 14, 2007Date of Patent: March 30, 2010Assignee: Bayer Schering Pharma AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
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Publication number: 20090026841Abstract: An electric power supply system which, in the event of a power failure, is capable of efficiently supplying electric power to household electric appliances in cooperation of a vehicle, including a mechanism supplying electric power outside the vehicle, with a stationary fuel cell system and also includes an electric power supply system using a power converter for converting direct current powers from a vehicle fuel cell and a stationary fuel cell into alternating current powers. The electric power supply system is constructed by a vehicle fuel cell provided on a fuel cell vehicle, a stationary fuel cell provided in a stationary power supply system, and a power converter for converting direct current powers from the vehicle fuel cell and the stationary fuel cell into alternating current powers.Type: ApplicationFiled: April 21, 2006Publication date: January 29, 2009Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventor: Osamu Nakanishi
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Publication number: 20080213813Abstract: To provide a novel apoptosis inducer, and a method of screening an apoptosis inducer. For example, an apoptosis inducer comprising inhibiting HDAC6 such as an antisense oligonucleotide to the gene of histone deacetylase 6 (HDAC6), and anti-cancer agent comprising this apoptosis inducer, and the present invention also provides a method of screening an apoptosis inducer that inhibits HDAC6, and more specifically a method of screening an apoptosis inducer said method comprising the steps of (1) determining whether or not a test substance inhibits histone deacetylase 6 (HDAC6) by using deacetylation of an acetylated substance that can be a substrate for histone deacetylase 6 (HDAC6) or decrease in the expression of histone deacetylase 6 (HDAC6) as an index; and (2) confirming, when inhibition is present, whether it induces apoptosis of the cell in vitro and/or in vivo.Type: ApplicationFiled: July 13, 2006Publication date: September 4, 2008Inventors: Osamu Nakanishi, Takayuki Tatamiya
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Publication number: 20080188489Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: ApplicationFiled: November 14, 2007Publication date: August 7, 2008Applicant: Schering AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
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Patent number: 7317028Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: GrantFiled: January 9, 2004Date of Patent: January 8, 2008Assignee: Schering AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
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Publication number: 20070288816Abstract: A semiconductor integrated circuit includes a logic circuit unit having a logic circuit and a first scan chain including a first scan chain to perform a scan chain for the logic circuit, and a memory unit having a memory, a BIST circuit, and a second scan chain to perform a scan test therefor. The two scan chains form a scan chain, and the first scan chain is disposed in an output side of the second scan chain. At a burn-in, along with setting the first scan chain to enable according to a scan enable signal, the second scan chain is set to disenable according to the scan enable signal and a memory test start signal, and stress is applied at the same time to the user logic circuit by a scan test and to the memory by a BIST.Type: ApplicationFiled: March 8, 2007Publication date: December 13, 2007Inventor: Osamu Nakanishi
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Publication number: 20070098816Abstract: An anticancer drug having a synergistic effect by combined use of a histone acetylase derivative such as N-(2-aminophenyl)-4-[N-(pyridin-3-ylmethoxycarbonyl) amninomethyl]benzamide (MS-275) and another anticancer active substance.Type: ApplicationFiled: May 26, 2004Publication date: May 3, 2007Inventors: Osamu Nakanishi, Tatsuo Sugawara, Hideyuki Migita, Yasuhiro Matsuba
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Patent number: 6960400Abstract: When power failure of a commercial power source is detected, an inverter interrupts power supply to a power line extending between the commercial power source and a load via a circuit breaker. Then the control mode of a load DC—DC converter is changed to a constant voltage control to maintain stable operation of a fuel cell. This allows the accessory DC—DC converter to supply power to accessories used for operating the fuel cell power generation system. Also, the quantity of city gas to be supplied to a reformer is changed to a quantity necessary for the fuel cell to generate power for driving the accessories. This makes it possible to avoid excessive production of hydrogen, thus improving energy efficiency of the fuel cell power generation system.Type: GrantFiled: December 23, 2002Date of Patent: November 1, 2005Assignees: Toyota Jidosha Kabushiki Kaisha, Aisin Seiki Kabushiki KaishaInventors: Koichiro Hara, Nobuki Hattori, Osamu Nakanishi, Shiroh Yamasaki
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Patent number: 6833209Abstract: A fuel-cell cogeneration system of electrical energy and hot water includes an off-gas burner for burning an off-gas from an anode electrode of a fuel cell, a reformer including a reformer burner for burning a mixture of air and fuel, a first heat exchanger provided at a downstream-side of stack cooling water, wherein the first heat exchanger is adapted to exchange heat from the off-gas burner with the stack cooling water from the fuel cell, to heat the stack cooling water, and a switch for switching a direction of flow of a reformed gas from the reformer, depending on an operation condition of the system and a demand for the hot water.Type: GrantFiled: March 25, 2002Date of Patent: December 21, 2004Assignee: Aisin Seiki Kabushiki KaishaInventors: Osamu Nakanishi, Kazuhiro Osada, Takashi Ishikawa
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Patent number: 6794392Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: GrantFiled: October 13, 1999Date of Patent: September 21, 2004Assignee: Schering AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
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Publication number: 20040147569Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: ApplicationFiled: January 9, 2004Publication date: July 29, 2004Applicant: Schering AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi
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Publication number: 20030216345Abstract: To provide a novel apoptosis inducer, and a method of screening an apoptosis inducer. For example, an apoptosis inducer comprising inhibiting HDAC6 such as an antisense oligonucleotide to the gene of histone deacetylase 6 (HDAC6), and anti-cancer agent comprising this apoptosis inducer, and the present invention also provides a method of screening an apoptosis inducer that inhibits HDAC6, and more specifically a method of screening an apoptosis inducer said method comprising the steps of (1) determining whether or not a test substance inhibits histone deacetylase 6 (HDAC6) by using deacetylation of an acetylated substance that can be a substrate for histone deacetylase 6 (HDAC6) or decrease in the expression of histone deacetylase 6 (HDAC6) as an index; and (2) confirming, when inhibition is present, whether it induces apoptosis of the cell in vitro and/or in vivo.Type: ApplicationFiled: May 15, 2003Publication date: November 20, 2003Applicant: Schering AGInventors: Osamu Nakanishi, Takayuki Tatamiya
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Publication number: 20030143447Abstract: The power generation mode of fuel cells included in a fuel cells power generation system, the quantity of power generation by the fuel cells, the working power used for a load, the amount of hot water kept in a hot water tank, the time, the occurrence of an abnormality in the system, and a request for regular inspection are displayed on a display unit of an operation display panel as numerical values and stepwise-variable graphical expression representing variations in quantity. The user is accordingly informed of the current driving conditions of the system and the working power used for the load, and sets the power generation mode of the fuel cells based on these pieces of information. This enables the user to adequately and readily control the operations of the system.Type: ApplicationFiled: January 31, 2003Publication date: July 31, 2003Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Naomichi Akimoto, Takeshi Masui, Koichiro Hara, Nobuki Hattori, Osamu Nakanishi, Shiroh Yamasaki, Yasuhito Noguchi
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Publication number: 20030139203Abstract: A telephone directory database is established in a mobile phone terminal. When a calling operation is executed in the mobile phone terminal, data included in the telephone directory database is sent out into the data network. A server computer in the central office may receive the data. The received data is registered into a database for backup data in the server computer. The backup data for the telephone directory database is reliably prepared in the server computer in this manner. A user of the mobile phone terminal is allowed to easily reestablish the telephone directory database in a new mobile phone terminal based on the backup data.Type: ApplicationFiled: July 12, 2002Publication date: July 24, 2003Applicant: FUJITSU LIMITEDInventors: Hun Hong Cho, Satoru Ueyama, Hiroki Teramoto, Osamu Nakanishi, Hiroshi Kosaki, Hiroshi Shinohara, Takuya Sakata, Yuuji Nakayama
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Publication number: 20030124400Abstract: When power failure of a commercial power source is detected, an inverter interrupts power supply to a power line extending between the commercial power source and a load via a circuit breaker. Then the control mode of a load DC-DC converter is changed to a constant voltage control to maintain stable operation of a fuel cell. This allows the accessory DC-DC converter to supply power to accessories used for operating the fuel cell power generation system. Also, the quantity of city gas to be supplied to a reformer is changed to a quantity necessary for the fuel cell to generate power for driving the accessories. This makes it possible to avoid excessive production of hydrogen, thus improving energy efficiency of the fuel cell power generation system.Type: ApplicationFiled: December 23, 2002Publication date: July 3, 2003Inventors: Koichiro Hara, Nobuki Hattori, Osamu Nakanishi, Shiroh Yamasaki
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Patent number: RE39754Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: GrantFiled: August 14, 2003Date of Patent: July 31, 2007Assignee: Schering AGInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
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Patent number: RE40703Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.Type: GrantFiled: October 3, 2006Date of Patent: April 28, 2009Assignee: Schering AktiengesellschaftInventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka