Abstract: Provided are a package for a skin drug solution holding body capable of further prohibiting impregnation unevenness of a drug solution, and a method of manufacturing the same. A face mask package in which a base material 1 used by attaching it to skin is impregnated with liquid cosmetics 2, and the base material 1 and the liquid cosmetics 2 of high viscosity are placed in a packaging bag 3 and vacuum-sealed. The base material 1 is in a sheet form, and the sheet-form base material 1 is stored in a folded state in the packaging bag 3 as a flat bag. It is preferable that a chamber-type vacuum sealing machine is used for vacuum-sealing. It is also preferable that the packaging bag 3 having the base material 1 and the liquid cosmetics 2 therein is pressed, while being sandwiched, prior to vacuum-sealing.